Genotyping, gene expression and proteomics applications demand effective disruption of biological samples to ensure high yields of DNA, RNA and protein. The TissueRuptor II system delivers thorough and rapid disruption of samples to fully release biomolecules, and also simultaneously homogenizes samples to facilitate subsequent purification procedures using QIAGEN kits (see table).
The TissueRuptor II is an integral part of QIAGEN's complete solution for sample management — from sample collection to purification and analysis of DNA, RNA and protein. Optimized protocols integrate sample disruption with biomolecule purification, enabling a streamlined, efficient workflow. In addition, a range of automated solutions allow purification and analysis of biomolecules at low to high throughputs.
QIAGEN also provides RNAprotect Tissue Reagent (to stabilize RNA) and Allprotect Tissue Reagent (to stabilize DNA, RNA and protein). Tissues collected in these reagents can also be easily disrupted with the TissueRuptor II.
QIAGEN purification kits compatible with QIAGEN disruption systems
|Analyte purified ||Sample type ||QIAGEN kit |
|RNA ||Easy-to-lyse tissue || |
|RNeasy Plus Kits |
|RNeasy Protect Kits |
|RNA ||Fiber-rich tissue ||RNeasy Fibrous Tissue Kits |
|RNA ||All types of tissue ||RNeasy Lipid Tissue Kits |
|RNeasy Universal Tissue Kits |
|RNA ||Plant tissue ||RNeasy Plant Mini Kit |
|RNA ||Yeast ||RNeasy Kits |
|RNA ||Bacteria ||RNeasy Protect Bacteria Kits |
|microRNA ||All types of tissue ||miRNeasy Kits |
|DNA ||Human tissue ||QIAamp DNA Kits |
|DNA ||Animal tissue ||DNeasy Blood & Tissue Kits |
|Protein ||Tissue ||Qproteome Mammalian Protein Prep Kit |
|Phosphoprotein ||Tissue ||PhosphoProtein Purification Kit |
|Glycoprotein ||Tissue ||Qproteome Glycoprotein Kits |
|DNA and RNA ||Tissue ||AllPrep DNA/RNA Kits |
|DNA, RNA, and protein ||Tissue ||AllPrep DNA/RNA/Protein Mini Kit |