PML-RARA bcr1 Kit is a ready-to-use kit for the quantification of PML-RARA bcr1 fusion transcripts using real-time PCR. The kit is based on the amplification and detection of specific PML-RARA bcr1 transcripts, relative to ABL control gene expression, in total RNA (see figures PML-RARA bcr1 gene transcript
and ABL control gene transcript
). The kit provides high levels of specificity, sensitivity, and reproducibility. Each ipsogen
PML-RARA bcr1 Kit provides 5 standard dilutions for PML-RARA bcr1 fusion gene and 3 standard dilutions for ABL. Use of the standards enables accurate quantification of transcripts. Standardization and validation of the quantification method has been established by Europe Against Cancer (EAC) and the ipsogen
PML-RARA kit is based on this technique.