What is the integrity of RNA from PAXgene Tissue fixed, paraffin-embedded (PFPE) tissue?
Like yield, RNA integrity depends on parameters, such as tissue type, period of cold ischemia, fixation time, processing protocol, age, and storage conditions of the PFPE block. For examples of the integrity of RNA in rat tissues under ideal workflow conditions, see Groelz et al., Exp Mol Pathol. 2013 Feb;94(1). For examples of the integrity of RNA from clinical samples, see Viertler et al., J Mol Diagn. 2012 Sep;14(5)