Investigator 24plex Kits use QIAGEN's fast-cycling PCR technology for rapid and reliable co-amplification of the CODIS and ESS markers, plus SE33, DYS391 and Amelogenin. Carefully designed primers reduce overlap of loci alleles, thereby minimizing the likelihood of data misinterpretation.
The innovative Quality Sensors provide additional information on sample quality and PCR success beyond the profile of the sample. With two Quality Sensors being amplified as a positive control, it is possible to determine:
- If amplification was successful
- If DNA was present in the sample
- If the sample was degraded
- If inhibitors in the sample prevented successful PCR
This additional information will greatly enhance your data analysis and will help you to make crucial decisions with respect to further sample processing. The Quality Sensors will help you reduce unnecessary re-runs, saving you time and money.
The two gender markers, Amelogenin and DYS391, have been optimized to produce small fragment sizes, making the gender typing extremely robust. Even for populations with Amelogenin-null mutations, this means no more failures with the essential gender typing, even with degraded or inhibited samples.