What are locked nucleic acids (LNA)?
Why use LNA?
Tm normalization – robust detection regardless of GC content
Superior single nucleotide discrimination
Superior results from challenging samples
LNA in miRNA studies
Broad applicability across application areas
The unique characteristics of LNA make it a powerful tool, not only for miRNA research but also for detection of low-abundance, short or highly similar targets in a number of applications.
Discover our LNA-enhanced research tools
QIAGEN offers a diverse portfolio of high-performance LNA-enhanced tools to help you get to scientific insights more quickly. Find the right tool for your particular application using the links below:
- Jensen et al. (2011) Evaluation of two commercial global miRNA expression profiling platforms for detection of less abundant miRNAs. BMC Genomics. 12:435. doi: 10.1186/1471-2164-12-435.