QIAGEN Paternity Testing Solutions - Use the Investigator Argus X-12 QS Kit for complex cases

8 QIAGEN Paternity Testing Solutions 09/2016 In some cases, normal autosomal STR analysis is not sufficient to solve a case. ChrX genotyping can complement the analysis of autosomal and ChrY markers very efficiently, especially in complex cases of kinship testing. The Investigator Argus X-12 QS Kit is the only commercially available kit that allows STR analysis using X-chromosomal analysis (Table 5). This is particularly powerful in special X-chromosomal lineage tracing. Use the Investigator Argus X-12 QS Kit for complex The features of the Investigator Argus X-12 QS Kit include: • Co-amplification of 12 ChrX markers (clustered in 4 linkage groups) and D21S11 as autosomal alignment marker, to minimize the risk of sample mix-up (Figure 7) • An integrated Quality Sensor for better decision making and data interpretation • Faster results using FRM 2.0 PCR chemistry that allows for a PCR speed of approx. 80 minutes • High sensitivity and inhibitor resistance • Optional protocols for direct amplification Dye Markers 6-FAM QS1 Amelogenin DXS10103 DXS8378 DXS10101 DXS10134 BTG DXS10074 DXS7132 DXS10135 BTY DXS7423 DXS10146 DXS10079 BTR HPRTB DXS10148 D21S11 Table 5. Investigator Argus X-12 QS Kit dyes and markers Figure 7. Alignment of D21S11. Sample profiles from the A: Investigator Argus X-12 QS Kit and the B: Investigator 24plex QS Kit, with highlighted D21S11 amplicons. Do you want to learn from other customers? See the interview at www.qiagen.com/ChrXuser A B

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