QIAGEN Paternity Testing Solutions - DNA purification in complex cases

4 QIAGEN Paternity Testing Solutions 09/2016 For standard kinship analysis, you may choose to skip DNA purification and move straight to Investigator STR GO! Kits. These assays permit direct amplification. However, for difficult cases, we recommend initial purification of DNA to attain the most reproducible results and run the widest selection of assays. In these cases, we offer a broad portfolio for all kind of sample throughput, including manual or automated processing, for trusted quality and performance (Table 2 and Figure 3). DNA purification in complex cases Table 2. Overview of QIAGEN’s DNA purification portfolio from low to high throughput Instrument Kit Max. throughput* (samples/day) Max. throughput* (samples/year) Technology QIAcube® QIAamp® DNA Investigator Kit 48 12,000 Spin columns EZ1® Advanced XL EZ1 DNA Investigator Kit 56 14,000 Magnetic bead cartridge QIAsymphony® SP/AS QIAsymphony DNA Investigator Kit 120 29,000 Magnetic bead cartridge STAR Q SP/AS Investigator STAR Lyse&Prep Kit 192 46,000 Magnetic bead *Calculations of throughput based on Good Practice Guidelines with pre- and post-PCR work separated by rooms and persons. Analysis done from sample to result including sample lysis (if necessary), hands-on time, PCR- and CE-run; data interpretation is not included. While the QIAamp DNA Investigator Kit, used manually or automated on the QIAcube, offers great flexibility and performance for low-throughput labs and small sample batches, we also offer a variety of automated solutions for labs that need larger batches or high-throughput testing. These include the EZ1 Advanced XL (for sample preparation), our QIAsymphony SP/AS (for sample preparation and assay setup) and our latest high-throughput instrument, the STAR Q SP/AS. QIAcube with QIAamp DNA Investigator Kit EZ1 Advanced XL with EZ1 DNA Investigator Kit QIAsymphony SP/AS with QIAsymphony DNA Investigator Kit STAR Q SP/AS with Investigator STAR Lyse&Prep Kit Figure 3. Overview of QIAGEN’s sample purification portfolio including chemistry and supportive automation. DNA Investigator Kit 4812,000 Spin columns Advanced XL EZ1 DNA Investigator Kit 5614,000 Magnetic bead cartridge SP/AS QIAsymphony DNA Investigator Kit 12029,000 Magnetic bead cartridge STAR Q SP/AS Investigator STAR Lyse&Prep Kit 19246,000 Magnetic bead

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