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Biopharma

Optimizing DNA clearance in high-salt, GMP-grade purification processes

Residual DNA and enzyme impurities are critical challenges in cell and gene therapy manufacturing. High-salt lysis improves yield, but also demands more from nucleases, especially under GMP conditions with strict regulatory limits.

In this white paper, you’ll learn:

  • Why DNA removal is harder in salt-rich workflows
  • How Saltonase® GMP-grade performs under high salt, pH and temperature
  • How the Saltonase® ELISA Kit supports accurate residual enzyme detection

Applicable for:
Viral vector manufacturing workflows, including AAV, lentivirus (LV) and virus-like particles (VLPs) in GMP settings.

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