Transition from manual to automated sample purification seamlessly with QIAGEN spin-column kits and the QIAcube Connect. Watch the videos below to see how.
Duration:1:04 minutes
Release date:24.06.2022
QIAcube Connect
Select the sample type, kit and starting material. The touchscreen displays the selected protocol and guides you through the instrument setup step by step.

The optical sensor checks the number and position of the loaded samples and ensures that the rotor adaptors are loaded correctly.

The ultrasonic sensor then confirms whether the buffer is sufficient for the protocol.

Finally, the optical sensor checks that the correct tip type and the number of tips are loaded. The QIAcube Connect then starts the protocol.

When the QIAcube Connect picks up a new tip, it passes it through a tip sensor to ensure that the correct tip type is used.

Lysis buffer is then added to each sample, and the filter tip is discarded.

The samples are incubated in the heatable shaker until lysis is complete.

Lysates are applied to the spin columns in the centrifuge.

The centrifuge lid closes. The centrifugation step enables nucleic acids to bind to the spin-column membrane.

Wash buffer is applied to each spin-column, and wash steps are performed.

The robotic gripper transfers each spin column from the wash to the elute position.

Elution buffer is applied to each spin column.

The centrifugation step enables elution of nucleic acids from the spin columns into an elution tube.

Run completed appears on the touchscreen and tablet, confirming run completion.

Get push notifications on instrument status so you can respond faster when needed by connecting your instrument to the QIAsphere app.

The UV light ensures effective worktable decontamination after the run.

Learn more about the QIAcube Connect UV-light decontamination procedure in this Application Note.

See it for yourself
Would you like a free, no-strings-attached demo? Request one through our online form.

This series of videos is not a replacement for the user manual. Read the user manual before working with the QIAcube Connect.

QIAcube Connect is designed to perform fully automated purification of nucleic acids and proteins in molecular biology applications. The system is intended for use by professional users trained in molecular biological techniques and the operation of QIAcube Connect.

For up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit instructions for use or user operator manual. QIAGEN instructions for use and user manuals are available at or can be requested from QIAGEN Technical Services (or your local distributor).