Pushing the boundaries of what's possible in cancer therapy
Liquid biopsy
Digital PCR in cancer research – Rare mutation detection and copy number variation analysis
Digital PCR can be harnessed to identify residual cancer below current detection levels, detect new mutations and duplications in cancer and monitor rare drug-resistance mutations. The QIAcuity Digital PCR System allows for increased sensitivity in the detection and absolute quantification of rare events/sequence variants because target quantification is independent of the number of amplification cycles.
Copy number variations (CNVs) of specific genes are involved in the development and progression of many cancers. Therefore, the quantitative analyses of CNVs at disease-associated loci provide insights into molecular mechanisms of diseases and facilitates the discovery of novel biomarkers. The QIAcuity Digital PCR System enables accurate detection of copy numbers in the genome, making itan indispensable tool for the subsequent analysis of copy number alterations underlying disease progression.
To help you take advantage of this highly precise technology, we offer a complete solution for digital PCR-based mutation detection and copy number variation studies.