Custom LNA Oligonucleotide Design and Applications

Guidelines for designing your own Custom LNA Oligonucleotides

The high affinity of an LNA-enhanced oligonucleotide to its complementary sequence results in dramatically improved specificity and sensitivity when compared with traditional DNA or RNA oligos. When designing LNA oligos, incorporation of LNA in a sequence strongly affects the properties of the oligonucleotide, so you must take great care to find the right design for your experimental purpose.