Expert insights: Unlocking the future of targeted NGS
From intelligent NGS panel design to high-precision data
The journey towards variant detection can be long and laborious, often riddled with uncertainties. All DNA fragments look the same. So you may often find yourself wondering whether you’re looking at a true variant or just an artifact. Distinguishing between a PCR error and a low-frequency mutation is yet another dilemma. Coverage gaps could be adding to your growing list of challenges. Endless bead purifications and multi-step targeted NGS library prep workflows mean you may be struggling to finish your day’s work on time while feeling the endless pressure to publish.
If you are perpetually plagued with these perplexing questions and overwhelmed about choosing the right targeted NGS panels for your project, read on.
We recently chatted with Dr. Barnaby Clark from Kings College Hospital about his experiences with targeted sequencing and, ultimately, the choice of NGS panels for his projects.