Science Matters


QC all the way: Starting material to the final NGS library

June 3, 2024

NGS core labs can conserve valuable time and resources using automated capillary electrophoresis on the QIAxcel Connect for sample and library quality control.

QIAxcel Connect, Instrument, Automation, IAS,analysis of low concentration nucleic acids with 3–5 bp resolution, DNA and RNA analysis

How to avoid wasting RNA-seq reads in metatranscriptomics

December 12, 2023

Struggling with RNA-seq optimization for metatranscriptomics applications? Don’t overlook rRNA removal. Our blog post reveals why.

Female scientist holding sample that turns into genetic code

Top 3 considerations for targeted sequencing of myeloid neoplasms

November 9, 2023

Targeted NGS can reveal the complex mutational landscape of myeloid neoplasms. What are the top 3 things you should consider before deciding on a panel? 

Female scientists discussing research in modern laboratory

Unfolding the cfDNA story: Q&A highlights from our webinar

August 1, 2023

Catch up on the Q&A session from our recent webinar on ultra-rare variant detection at 0.1% VAF from cfDNA.


From rare to revealed: Detect those all-important but elusive variants from cfDNA

June 14, 2023

Detect ultra-rare variants at 0.1% variant allele frequency from cfDNA using a streamlined, 8-hour library prep workflow.

illustration of hands holding a bowl

Answers to your burning questions on AMR detection technologies revealed

April 20, 2023

Our AMR webinar Q&A session covered a lot of useful info – from sample prep tips to advice on NGS- and dPCR-based AMR detection. We’ve compiled it all in our blog post.

Microbes research

Battling known and unknown threats with NGS-based AMR detection

February 27, 2023

Looking to accelerate your antimicrobial resistance (AMR) research? Discover the benefits of hybrid capture-based NGS panels for AMR detection.

Microbiome, AMR, Antimicrobial resistance, campaign visual for AMR 2023

Expert insights: Unlocking the future of targeted NGS

November 3, 2022

Choosing the right targeted next-generation sequencing panel can make all the difference to your project. Discover how researchers are accelerating variant detection using QIAseq NGS technology.

QIAseq, QIAseq Targeted DNA Pro, Barnaby Clark, Kings College, DNA-seq

Top 3 tips for low-input RNA-seq success

November 2, 2022

If you’re struggling to maximize gene expression insights from minimal RNA amounts, then check out our blog post on the top 3 tips for robust RNA-seq data from low-input RNA.

Visual dedicated to the RNAseq campaign, woman in deep thoughts

What is right for you? 16S/ITS sequencing Vs Whole genome metagenomics

June 23, 2022

It can be difficult to decide which microbial NGS detection method is suitable for your project and lab. Here are 3 questions to ask yourself as you prepare your microbial experiment:

Microbiome and GC content, microbiome, gc content, ungs, ngs, Dylan Barbera, webinar

Got microbial profiling questions? We’ve got you covered

June 21, 2022

Identifying microbes and understanding how they affect the overall human health and disease is of utmost importance. Next-generation sequencing (NGS) allows researchers to characterize...

Microbial profiling teaser image

Flushing out SARS-CoV-2 variants from wastewater samples using NGS

May 5, 2022

We interviewed Dr. Davida Smyth in mid-2021 about how whole genome NGS helped her detect circulating SARS-CoV-2 variants in wastewater and even reveal new mutations.

Scientist flushing out SARS-CoV_2 variants in laboratory using NGS

Top 20 FAQs on targeted NGS using QIAseq Targeted DNA Pro Panels

May 5, 2022

Targeted NGS has been transformed with the launch of new QIAseq Targeted DNA Pro Panels. But how? Get acquainted with the new panels and find answers to the top 20 FAQs.

Young scientist using QIAseq Targeted DNA Pro Panels

Hitting the right targets: Maximizing the potential of targeted NGS in cancer research

March 29, 2022

Explore how targeted next-generation sequencing is helping cancer researchers detect actionable mutations and develop biomarkers to evaluate the efficacy of treatments.

Female scientist working on a computer in a laboratory

Living with a rare disease amidst COVID

March 8, 2022

Read this blog and take a moment to reflect upon how the pandemic impacted rare disease patients and researchers.

Rare Diseases Day

Certainty at a time of uncertainty: An accurate picture of circulating SARS-CoV-2 variants

December 3, 2021

We explore how whole viral genome sequencing has been instrumental in informing public health labs about the prevalence of circulating SARS-CoV-2 variants.

QIAseq SARS-CoV-2 kit, campaign visual for QIAseq DIRECT Library Kit, two scientists in a laboratory working on computer screens,

Highlights from the ASHG 2021 virtual conference 

October 14, 2021

Check out the highlights from the ASHG 2021 virtual conference, plus exciting, new solutions and technologies for human genetics research. 

Evening event, invite image for general event, shadow of people in front of windows, blue, yellow colors, night

Top 6 FAQs on RNA fusion analysis

August 24, 2021

Explore the answers to the top 6 FAQs on RNA fusion analysis. Get tips and advice on optimizing your RNA fusion workflow and enhancing biomarker detection.

cg qiaseqmm brca teaser

Getting to the Heart of miRNA Profiling

August 11, 2021

Explore how researchers at the Texas Heart Institute uncovered novel disease insights through  miRNA profiling using QIAGEN’s innovative miRNA-seq technology.

Scientist in the laboratory

Get to know Jörg Tost, epigenomics researcher

May 20, 2021
To get a better handle on the past, present and future of epigenomics research and its implications for medicine, we sat down with Dr. Jörg Tost, an expert in methylation detection technology.
Dr. Jörg Tost with his team

Webinar roundup: From targeted sequencing to multimodal sequencing

March, 2021 

If you’re looking for novel or known variants associated with cancer, targeted sequencing is an efficient method of choice. By focusing on specific genomic regions of interest vs. the entire genome, you can increase...

Young scientist having a webinar with a laptop in a office

Methylation status reveals the purity of derived cells that may one day be used for hemophilia A therapy

March 11, 2021 

Epigenetic regulation across the genome, and methylation patterns in particular, are important modulators of basic biological processes, as well as the switch between health and disease.

DNA Helix

An end to the rare disease diagnosis labyrinth

January 2, 2021 

For many individuals, receiving a diagnosis for even common medical conditions can be tricky. Doctors’ appointments need to be made, tests need to be run.

Colored hands as sign for rare disease day

Q&A with the methylation analysis experts: your epigenomic questions answered

November 3, 2020

In a recent webinar, “Unlock liquid biopsy samples with NGS-based methylation detection from 10 ng DNA”, we discussed how to take your targeted methylation analysis to the next level using an NGS-based approach. The audience had some insightful questions!


Ribosomal RNA removal: The most underestimated step in RNA-seq optimization

September 12, 2019

Hematology team member and researcher, Dr. Fabienne Desmots-Loyer at CHU – Hospital Pontchaillou, Rennes, France was performing RNA-seq of paired patient follicular lymphoma...

Dr. Fabienne Desmots-Loyer

Automate and accelerate: Focus on insights, not library prep

June 5, 2019
The faster you can prepare high-quality NGS libraries, the faster you can proceed with sequencing your sample and uncovering insights that accelerate your understanding of its underlying biology. But what if you have thousands of samples? Issues...
Automate and accelerate: Focus on insights

RNA-seq Week 2018 – valuable insights and Q&A from the webinar series

January 23, 2019
Life science research is constantly on the edge of new technology developments. This trend is especially apparent in advanced transcriptomics and gene expression research. In December 2018, we hosted “RNA-seq Week”, where we…
RNA-seq Week 2018 – valuable insights and Q&A from the webinar series

Find every variant that matters – head-to-head comparison of targeted sequencing methods

January 22, 2019
In precision medicine, only a handful of DNA variants are going to be relevant for a specific disease or a targeted treatment. Identifying these variants can be difficult, depending on the DNA sample, the specific gene or region and the methodology...
Find every variant that matters – head-to-head comparison of targeted sequencing methods

Having issues with primer dropouts in your 2-primer amplicon-based panel? You should!

June 7, 2018
Don’t you hate seeing coverage gaps in your NGS panel after you’ve run your precious samples? Especially when the reason for the gap is as simple as primer dropouts? What’s even worse is that filling this gap might require a complete re-design of...
Having issues with primer dropouts in your 2-primer amplicon-based panel

Don’t settle for an amplicon variant assay – build an amplicon sequencing assay

June 5, 2018
There is a misconception out there that amplicon sequencing is beneficial only if you are interested in hotspots. Not true! Amplicon sequencing is beneficial regardless of the regions you are interested in, whether these are hotspots or…
Female scientist

QIAseq and Single Primer Extension Chemistry: Redefining Amplicon-Based NGS

January 29, 2018
Targeted NGS has been widely used for the detection and confirmation of genetic changes, yet there are technical challenges that undermine precise quantification and confound analyses. Multiplex PCR and nested PCR-based library...
QIAseq and Single Primer Extension Chemistry: Redefining Amplicon-Based NGS