Why does the QIAcube sometimes fail to pick up the tips or pick up wrong tips?
FAQ ID -3131

Customers are advised to use dedicated Qiagen tips to perform runs on the QIAcube. Ensure correct tips are loaded properly into the tip box.  If a 200ul tip has been loaded into a 1000ul tip box, it will be used as a 1000ul tip. If the QIAcube fails to pick up the tip, it could be due to a dirty tipcheck sensor or a defective O-ring. In that case, cleaning the sensor and changing the O-ring should rectify the problem.  Customers are advised to perform the tightness test to confirm whether the O-ring needs to be changed.