Can sections of PAXgene Tissue fixed, paraffin-embedded (PFPE) tissue be used for other histochemical staining techniques, such as PAS?

Human tissue samples treated with the PAXgene Tissue System were successfully used for periodic acid schiff (PAS), resorcin fuchsin, sirius red, and Gomori staining (Kap et al., PLoS ONE 6(11): e27704). However, to achieve the same staining intensities with both PFPE and formalin-fixed, paraffin-embedded (FFPE) samples, it may be necessary to adjust incubation times.


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