How are siRNAs introduced into C. elegans?

Two methods have been used; soaking worms in siRNA is successful and worms can be fed bacteria expressing the siRNA (from a plasmid after transformation). REFERENCES: RNAi in C. elegans: Soaking in the Genome Sequence Hiroaki Tabara, Alla Grishok, and Craig C. Mello 1998. Science 282:430. RH Plasterk and RF Ketting The silence of the genes. Curr Opin Genet Dev, Oct 2000; 10(5): 562-7.

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