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Tuberculosis testing

LIAISON QuantiFERON Gold Plus II - advanced TB test automation

Boost your productivity and efficiency with the new LIAISON QuantiFERON-TB Gold Plus II

The LIAISON TB test combines the world’s leading tuberculosis (TB) testing technology with the first – and only – fully automated detection system currently available. Get FDA and IVDR approved walkway automation of your QuantiFERON analytical workflow on a single versatile diagnostic testing platform.

What is LIAISON QuantiFERON-TB Gold Plus II?

LIAISON QuantiFERON-TB Gold Plus II is an automated, high-throughput test for tuberculosis infection. It combines the reliable technology of QuantiFERON-TB Gold Plus Blood Collection Tubes with a streamlined workflow on Diasorin’s LIAISON XS and XL analyzers. It’s the only FDA-approved, CE-marked and WHO-recommended automated TB test with unique CD8 T-cell technology, providing a more complete picture of the immune response to TB. 

Advantages of LIAISON QuantiFERON-TB Gold Plus II

The LIAISON TB test automates TB infection testing with support for continuous loading or sample batching.

Now it also features improved speed, capacity and efficiency with the same excellent clinical performance:

  • 25% faster – initial result in 32 minutes on LIAISON XL
  • 75% higher throughput – up to 171 tests/hour and 42 patients/hour
  • Improved reagent design to maximize assay efficiency

What are the benefits of using LIAISON automation for TB testing?

The LIAISON TB test lets you detect TB infection in only one step. Load your samples in <1 minute – no further handling or additional instruments required.

  • Scale up or internalize your TB testing
  • Reduce costs and reallocate staff time
  • Shorten turnaround time
  • Consolidate diagnostic tests on LIAISON family analyzers

LIAISON QuantiFERON-TB Gold Plus II is part of a large menu of specialized immunodiagnostic assays available on LIAISON automation systems.

Increase your test capacity with LIAISON XS and XL

LIAISON QuantiFERON-TB Gold Plus II run on low/mid or high throughput Diasorin LIAISON analyzers with available connectivity to Total Lab Automation (TLA). Preanalytical automation options are also available for aliquoting blood to the QFT-Plus Blood Collection Tubes.

Streamline your TB infection testing with front-end automation

Facing pressure to reduce hands-on time amid growing test volumes and staffing challenges? Blood samples collected into a single lithium- or sodium-heparin tube can be transferred to the QFT-Plus Blood Collection tubes automatically using the Hamilton Aliquot STARlet workstation or Tecan Fluent Mix & Pierce workstation.

Kola Ogunrinola
Kola Ogunrinola,
PhD, SH(ASCP), FIBMS, CSci

Director of Operations, Pathology 
St. Luke’s Health System,
Boise, Idaho 
Ruel N Del Rosario
Ruel N. Del Rosario,
MSHSA, MT (ASCP)

Director, Laboratory Services Eisenhower Medical Center,
Rancho Mirage, CA

How does the LIAISON QuantiFERON test work?

The LIAISON TB test uses a chemiluminescent immunoassay (CLIA) to detect TB infection. Whole blood samples are incubated in QuantiFERON-TB Gold Plus Blood Collection Tubes, which stimulate in vitro immune responses to peptide antigens associated with Mycobacterium tuberculosis infection. The LIAISON immunoassay then measures interferon-γ (IFN-γ) in the stimulated plasma samples to determine if TB infection is likely.

Can the LIAISON test improve my lab’s TB testing?

The LIAISON QuantiFERON test improves TB testing by automating analysis on the LIAISON XS or XL platforms, reducing manual steps and errors. LIAISION QuantiFERON-TB Gold Plus II offers improved test throughput with the excellent clinical performance you trust. Choose continuous sample loading or sample batching and test up to 42 patients every hour. Results are fully traceable to the individual tube ID and directly populated to EMR.

Who should use the LIAISON TB test?

Automated TB testing benefits high-throughput clinical labs, public health laboratories, immigration clinics and occupational health centers. It is ideal for integrated hospital networks that need fast, mid- and high-volume testing of current and new-hire healthcare workers . The LIAISON QuantiFERON test reduces manual labor, ensures consistency and supports timely detection of TB infection in patients at elevated risk .

What is the difference between LIAISON QuantiFERON-TB Gold Plus I and II? 

The LIAISON II test features a new Conjugate Anti-IFN-γ Monoclonal Antibody engineered for improved performance and reliability in IFN-γ detection.

   LIAISON QuantiFERON-TB Gold Plus  LIAISON QuantiFERON-TB Gold Plus II
 Speed  LIAISON XS: 49 minutes to first result
 LIAISON XL: 45 minutes to first result
 LIAISON XS: 33 minutes to first result
 LIAISON XL: 32 minutes to first result
 Capacity  LIAISON XS: up to 17 patients/hour 
 LIAISON XL: up to 25 patients/hour
 LIAISON XS: up to 21 patients/hour 
 LIAISON XL: up to 42 patients/hour
Are you ready to add automated TB testing?
Streamline your latent TB testing with the LIAISON QuantiFERON-TB Gold Plus II test.
On-demand webinar: First-hand experiences with the LIAISON QuantiFERON test

Join Ruel Del Rosario as he demonstrates the benefits of internalizing your TB testing. He'll detail the process and outcomes of Eisenhower Laboratory's transition from send-out to automated in-house testing.

Tuberculosis management, QFT, LIAISON QuantiFERON-TB Gold Plus, In collaboration with DiaSorin, LIAISON XL analyzer, QFT tubes in rack
See how two scientists are quickly and automatically detecting latent TB

The UK and US have advanced healthcare systems, yet tuberculosis remains a critical public health concern. See how two committed scientists separated by one vast ocean rely on the same tool to detect TB before it spreads to others or develops into active and highly contagious TB disease.

A lab in Doncaster receives multiple samples from communities susceptible to TB. Michelle Poole, Chief biomedical Scientist at Doncaster Royal Infirmary explains how the lab gets trustworthy and fast results with LIAISON QuantiFERON-TB Gold Plus.

*QuantiFERON-TB Gold Plus Blood Collection Tubes by QIAGEN and LIAISON Analyzer by DiaSorin.

Product claims may differ from country to country based on regulations and approvals. Contact your country representative for further details.

Frequently asked questions

Product claims and availability may differ from country to country based on regulations and approvals. Contact your country representative for further details.