Next-generation sequencing

Key applications

Impactful discoveries powered by NGS

Next-generation sequencing (NGS) can deliver unprecedented insights, unraveling the intricacies of the genome and transcriptome in biomarker research, gene expression studies, viral epidemiology and disease surveillance, as well as comprehensive genomic profiling to identify variants implicated in cancer and other diseases. However, challenges such as workflow optimization, customization and data analysis and interpretation can hinder progress. Partner with QIAGEN to unlock the full potential of NGS with innovative QIAseq technologies.

Meet the recipients of the 2021 QIAGEN RNA-seq Grant

In 2021, we invited researchers to explore the potential of RNA-seq for their research by applying for a QIAGEN RNA-seq Grant. We received an astounding 2400 applications and are pleased to announce the grant recipients.

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Enhance your core facility offering

Learn how our partnership with leading service centers and core labs overcome typical lab bottlenecks and advance your research.

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Automate and accelerate your library prep

Automating your NGS means more consistency between runs, less batch processing errors, fewer re-runs, plus significant time and cost savings.

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Uncover more biology with NGS technology
Navigate the complexity of the NGS world with ease by partnering with QIAGEN. Benefit from extensive expertise, tailored solutions and market-leading informatics so you can achieve:
- Accurate results from even the most challenging of samples
- Faster turnaround times using streamlined and optimized workflows
- Meaningful insights from complex NGS data
From challenging samples to integrated insights
Got challenging samples? Don’t write them off yet! With QIAseq, you can access the most difficult regions of the genome and derive impactful insights from the toughest of samples.
- FFPE and liquid biopsy samples
- Limited DNA and RNA samples
- GC-rich regions
- Low-frequency variants
- Exonic regions

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Application highlights

High-throughput genomic surveillance of emerging SARS-CoV-2 Delta, Mu and Omicron variants

The emergence of new, highly transmissible SARS-CoV-2 variants has elevated the need for high-throughput whole viral genome sequencing to accelerate genomic surveillance efforts. Cataloging new variants and evaluating the impact of the accumulated mutations is critical for vaccine development and effective public health measures. Explore how our high-performance, scalable NGS workflows with integrated bioinformatics facilitate accurate SARS-CoV-2 variant detection and phylogeographic tracking.

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Go from RNA-seq to gene expression insights with ease

Struggling to make sense of your RNA-seq data? Take the stress out of data analysis and fast-track your path to gene expression insights with the new RNA-seq Analysis Portal. Designed for biologists and fully integrated with GeneGlobe, this intuitive, web-based solution is now included with QIAseq RNA-seq and miRNA-seq kits. Simply upload your sequence files into the RNA-seq Analysis Portal, start your analysis and go from FASTQ files to focused insights into the top 10 canonical pathways, upstream regulators and diseases using powerful IPA knowledge bases.

Expanding disease insights with exome sequencing

The coding portion of the genome holds tantalizing information on multiple diseases. Unlocking these details through exome sequencing can reveal powerful insights into disease-associated variants. However, coverage issues, long turnaround times and data analysis bottlenecks can diminish progress. Explore a time-saving workflow that seamlessly combines uniform exome coverage with streamlined secondary analysis, rapid variant filtering and annotation.

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Explore benefits of QIAseq NGS

Get in touch to see how QIAseq NGS solutions can transform your research.

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Accelerate integrated insights from NGS data with maximum ease

You’ve run your benchtop experiment and finally achieved NGS data. But what does it all mean? Demystify data analysis and interpretation with our intuitive bioinformatics tools.

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Featured new products

QIAseq DIRECT SARS-CoV-2 Kits
High-throughput, 50% faster SARS-CoV-2 NGS solution.
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RNA-seq Analysis Portal
Simplify RNA-seq and miRNA-seq data analysis and achieve gene expression insights with ease.
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QIAseq Fusion XP Targeted Panels
Combine RNA fusion analysis, gene expression profiling and SNV calling in a single assay.
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QIAseq FastSelect Custom RNA Removal Kit
Remove any RNAs you wish from your RNA-seq library with easy customization.
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QIAseq Human Exome Kits
Sample to disease insights with exome sequencing.
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Check out the Workflow Configurator

This smart online tool can help you find the right products for every step of your workflow.

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Useful resources to fuel your research

Science Matters blog
Stay up-to-date on the latest developments in the world of genomics. Check out interesting articles, researcher interviews and more in our exciting blog.
Read the blog
On-demand webinars
Access our extensive range of on-demand webinars for useful tips and tricks, advice on overcoming typical workflow challenges and more.
VIEW WEBINARS
Key publications
Discover the impact of QIAseq NGS solutions in diverse research applications by browsing through our compilation of publication highlights.
VIEW CITATIONS

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Without NGS, a modern laboratory is unimaginable today.

Prof. Paul Hofman, CHU Nice, France

Inspiration from the lab bench
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featured research success stories

Sequencing COVID-19 mutations after jumping species

Dr. Mette Christiansen, Head of the Diagnostic NGS Core Facility, Molecular Medicine (MOMA) at Aarhus University Hospital, discusses the importance of sequencing every positive sample to develop a clear picture of circulating SARS-CoV-2 variants and how QIAseq NGS technologies facilitated these efforts.
Accelerating human and bacterial co-expression studies with high-quality RNA-seq data

Dr. Marie Adams from the Van Andel Institute discusses how QIAseq FastSelect technology helped conquer the challenges of generating high-quality RNA-seq data for human and bacterial co-expression studies from the same RNA sample.
Increasing RNA-seq sensitivity in cancer research

Researchers from the University of Houston discuss how powerful QIAseq FastSelect rRNA removal technology transformed their research, allowing them to retrieve useful RNA-seq data from FFPE RNA.
Defending against cancer by manipulating the immune system using NGS technology

Dr. Nathalie Labarrière from the University of Nantes describes her work using QIAseq Immune Repertoire RNA Library Kits to target colon cancer and melanoma tumors in new immuno-oncology therapies.
Driving insights into pancreatic cancer risk using custom NGS panels

Dr. Fergus Couch from the Mayo Clinic discusses how QIAseq Targeted DNA Panels played a vital role in a longitudinal case-control study on the risk of pancreatic cancer.
Ensuring uniform coverage enables heterozygous mutation detection in cancer research

Dr. Egbert Schulze from the Endocrinology and Nuclear Medicine Community Practice, Heidelberg, discusses how the all-enzymatic QIAseq FX workflow enabled uniform coverage and helped him achieve reliable sequencing results in his research.

Sequencing COVID-19 mutations after jumping species
Accelerating human and bacterial co-expression studies with high-quality RNA-seq data
Increasing RNA-seq sensitivity in cancer research
Defending against cancer by manipulating the immune system using NGS technology
Driving insights into pancreatic cancer risk using custom NGS panels
Ensuring uniform coverage enables heterozygous mutation detection in cancer research