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Cignal Reporter Assay Kits

For rapid, sensitive, and quantitative assessment of signal transduction pathway activation

  • Rapid analysis of signal transduction pathway regulation
  • Exceptional sensitivity and specificity
  • Transfection-ready constructs
  • Includes positive and negative controls
  • Real-time live cell quantification (GFP format)

Cignal Reporter Assays provided in the Cignal Reporter Assay Kit enable rapid, sensitive, and quantitative assessment of signal transduction pathway activation by measuring the activities of downstream transcription factors. Two reporter systems are available: dual-luciferase format and GFP format.

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Cignal Reporter Assay Kits are intended for molecular biology applications. These products are not intended for the diagnosis, prevention, or treatment of a disease.


0
TNFα activates NFkB signaling activity in a dose-dependent manner.
293 H cells were transfected with Cignal NFkB Reporter Assay, negative or positive control. After 24 hours, cells were treated with different doses of hTNFα for a further 24 hours. Dual-luciferase assays were performed, and reporter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and standard deviation is shown.
1
Assessing RNA interference phenotypes.

Cignal p53 Reporter Assays showed that p53 siRNA treatment abolished p53 transcription activity. HCT 116 cells were transfected with p53 reporter, negative control, and positive control, together with p53 siRNA or negative control siRNA. Dual-luciferase assays were performed. Reporter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and the standard deviation is shown.

2
Assessing overexpression phenotypes.

Cignal RBP-Jκ Reporter Assay showed upregulation of Notch signaling activity after overexpression of activated Notch1. 293 H cells were transfected with RBP-Jκ reporter, negative control, and positive control. After 24 hours, cells were infected with 100 MOI of recombinant adenoviruses expressing activated Notch1 (Ad-NICD) or 100 MOI of recombinant adenovirus expressing GFP (Ad-GFP) for another 18 hours. Dual-luciferase assays were performed. Reporter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and the standard deviation is shown.

3
Verification of small molecule drug candidate.

Cignal Retinoic Acid Response Element (RARE) Reporter Assay reported elevated retinoic acid receptor pathway activity after the treatment of all trans-retinoic acid (ATRA). CHO-K1 cells were transfected with RARE reporter, negative control, and positive control. After 16 hours, medium was changed to assay medium. After 24 hours, cells were treated with 1 µM all trans-rectinoic acid (ATRA) for 6 hours. Dual-luciferase assay was performed, and promoter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and the standard deviation is shown.

4
Cignal Reporter Assay shows that hTNFa activated NFkB signaling pathway.
293 H cells were transfected with the Cignal NFkB-GFP Reporter Assay or negative control. After 16 hours, medium was changed to assay medium. After 24 hours, cells were treated with 10 ng/ml TNFα. After 18 hours, medium was removed from the wells and fluorescence activity was measured using a fluorometer. The fluorescence activity present in treated and nontreated negative control wells was subtracted from the fluorescence activity in treated and nontreated Cignal NFkB-GFP Reporter Assay wells and relative fluorescence activities expressed as arbitrary units. Experiments were performed in triplicate and the standard deviations are shown.
5
Cignal Reporter Assay measures activation of serum response factor (SRF) transcription activity.

293 H cells were transfected with the Cignal SRF-GFP Reporter Assay or negative control. After 16 hours, medium was changed to assay medium. After 24 hours, cells were treated with 10 ng/ml PMA and 10% serum. After 18 hours, medium was removed from the wells and fluorescence activity was measured using a fluorometer. The fluorescence activity present in treated and nontreated negative control wells was subtracted from the fluorescence activity in treated and nontreated Cignal SRF-GFP Reporter Assay wells and relative fluorescence activities expressed as arbitrary units. Experiments were performed in triplicate and the standard deviations are shown.

6
Cignal Reporter Assay procedure.
7
Cignal Reporter Assay principle.
Performance
Principle

Cignal Reporter Assays consist of multiple repeats of a specific transcription factor’s binding site and basic promoter elements to drive the expression of a reporter gene (firefly luciferase or GFP). These reporters are powerful tools in functional genomics and drug discovery for assessing pathway activity. When the pathway is activated or inhibited by a drug candidate, gene knockdown, overexpression, or peptide, luciferase or GFP reporter activity is modulated and can be measured quantitatively and rapidly (see figure "Cignal Reporter Assay principle"). The Cignal Reporter Assays are available as transfection-ready constructs utilizing two reporter systems: the dual-luciferase reporter or the GFP reporter (see flowchart "Cignal Reporter Assay procedure").

The dual-luciferase format is an end-point assay providing unsurpassed sensitivity, specificity, and signal-to-noise ratios. This format is available for all Cignal Reporter Assays. Each assay includes a pathway-focused transcription factor reporter and a noninducible negative control, as well as luciferase and GFP positive controls.

The GFP format is an outstanding method for monitoring live cell pathway regulation, with single cell resolution. It includes a pathway-focused transcription factor reporter and positive and negative controls.

Procedure

Cignal Reporter Assays include a preformulated, transfection-ready pathway reporter (dual-luciferase or GFP), plus a positive and negative control. The inducible pathway reporter and noninducible negative control are transfected and subjected to experimental treatments in parallel.

Dual-luciferase

Dual-luciferase results are calculated for each transfectant. The change in the activity of each signaling pathway is determined by comparing the normalized luciferase activities of the reporter in treated versus untreated transfectants. The identically treated negative control transfectants serve as a specificity control. The positive control serves as a control for transfection efficiency, by monitoring firefly luciferase and Renilla expression.

GFP

GFP expression is quantified using a flow cytometer, fluorescence microscope, or fluorometer. The change in the activity of each signaling pathway is determined by comparing the GFP activities in treated versus untreated transfectants. The identically treated negative control transfectants serve as a specificity control. The positive control serves as a control for transfection efficiency, by monitoring GFP expression from the constitutively expressing CMV-GFP reporter.

Applications

Cignal Reporter Assays are powerful tools in functional genomics, proteomics, and drug discovery for assessing the biological impact of pathway inhibition or activation with siRNAs, proteins, and small molecule compounds.

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Brochures & Guides (1)
For cell-based analysis of pathway signaling activity
Show details
Kit Handbooks (1)
Transfection Protocols (2)
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Transfection protocols for specific cell types and plate formats that save you the time and effort of adapting existing protocols to fit your requirements. Simply select the cell type, nucleic acid, and culture format to receive a QIAGEN transfection protocol to print out or download in convenient PDF format.
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References
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HIF Reporter Assay Kit Cignal Reporter Assay Kits
Introduction
The Cignal HIF Reporter Assay Kit is designed to monitor the activity of hypoxia signaling pathways in cultured cells. The hypoxia-inducible factor-1 (HIF-1) protein is a key regulator of oxygen homeostasis and plays significant roles in cancer progression as well as in cardiovascular diseases. The HIF reporter is a mixture of an inducible HIF-responsive luciferase construct and a constitutively expressing Renilla construct (40:1). The HIF-responsive luciferase construct encodes the firefly luciferase reporter gene under the control of a minimal (m)CMV promoter and tandem repeats of the hypoxia response element (HRE). We have experimentally optimized the number of response elements as well as the intervening sequence between response elements to maximize the signal to noise ratio. The constitutively expressing Renilla construct encodes the Renilla luciferase reporter gene under the control of a CMV immediately early enhancer/promoter and acts as an internal control for normalizing transfection efficiencies and monitoring cell viability. Using a simple dual-luciferase assay, you can easily monitor the activity of HIF-mediated hypoxia signaling pathway and determine the effect of various treatments, such as gene knockdown, over-expression, and chemical compounds on this pathway.
CCS-007L

The Cignal HIF Reporter Assay detects activation of the hypoxia pathway. HepG2 cells were transfected with Cignal HIF Reporter, negative control, and positive control (for the transfection protocol, refer to the Cignal Reporter Assay Handbook). After 16 hours of transfection, medium was changed to assay medium (Opti-MEM + 0.5% FBS + 0.1 mM NEAA + 1 mM sodium pyruvate + 100 U/ml penicillin + 100 µg/ml streptomycin). After 28 hours of transfection, cells were treated with 100 µM and 250 µM CoCl2 for 18 hours. A dual-luciferase assay was performed, and promoter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate, and the standard deviation is indicated. The Cignal HIF Reporter measured a 4-fold increase in HIF1 transcription activity and, in turn, showed activation of hypoxia pathway by CoCl2.
Name Cignal HIF Pathway Reporter Assay Kit (LUC) (CCS-007L)
Official symbol EPO [Human]
Official name erythropoietin
Species Human (Homo sapiens)
Entrez Gene ID 2056
Transcript(s) for this gene NM_000799 (1340 bp), ENST00000252723
Official symbol Epo [Mouse]
Official name erythropoietin
Species Mouse (Mus musculus)
Entrez Gene ID 13856
Transcript(s) for this gene NM_007942 (715 bp), NM_001312875 (712 bp)
Official symbol Epo [Rat]
Official name erythropoietin
Species Rat (Rattus norvegicus)
Entrez Gene ID 24335
Transcript(s) for this gene NM_017001 (1395 bp), XM_006249101 (1520 bp)
Official symbol LDHA [Human]
Official name lactate dehydrogenase A
Species Human (Homo sapiens)
Entrez Gene ID 3939
Transcript(s) for this gene NM_001135239 (2052 bp), NM_001165414 (2323 bp), NM_001165415 (1957 bp), NM_001165416 (2102 bp), NM_005566 (2226 bp), NR_028500 (2108 bp), ENST00000227157, ENST00000379412, ENST00000396222, ENST00000422447, ENST00000430553, ENST00000540430, ENST00000542179, ENST00000625635
Official symbol Ldha [Mouse]
Official name lactate dehydrogenase A
Species Mouse (Mus musculus)
Entrez Gene ID 16828
Transcript(s) for this gene NM_001136069 (1854 bp), NM_010699 (1661 bp), XM_001002669 (1511 bp)
Official symbol Ldha [Rat]
Official name lactate dehydrogenase A
Species Rat (Rattus norvegicus)
Entrez Gene ID 24533
Transcript(s) for this gene NM_017025 (1609 bp), XM_001080828 (1648 bp), XM_006229232 (1774 bp)
Official symbol ANGPTL4 [Human]
Official name angiopoietin-like 4
Species Human (Homo sapiens)
Entrez Gene ID 51129
Transcript(s) for this gene NM_001039667 (1791 bp), NM_016109 (1843 bp), NM_139314 (1905 bp), ENST00000598255, ENST00000594348, XM_005272484 (1957 bp), XM_005272485 (1843 bp), ENST00000301455, ENST00000393962
Official symbol Angptl4 [Mouse]
Official name angiopoietin-like 4
Species Mouse (Mus musculus)
Entrez Gene ID 57875
Transcript(s) for this gene NM_020581 (1916 bp), ENSMUST00000174872
Official symbol Angptl4 [Rat]
Official name angiopoietin-like 4
Species Rat (Rattus norvegicus)
Entrez Gene ID 362850
Transcript(s) for this gene NM_199115 (1871 bp)
Official symbol CCNG2 [Human]
Official name cyclin G2
Species Human (Homo sapiens)
Entrez Gene ID 901
Transcript(s) for this gene NM_004354 (5489 bp), ENST00000514756, ENST00000316355, ENST00000354403, ENST00000395640, ENST00000502280, ENST00000509972
Official symbol Ccng2 [Mouse]
Official name cyclin G2
Species Mouse (Mus musculus)
Entrez Gene ID 12452
Transcript(s) for this gene NM_007635 (2510 bp), ENSMUST00000153260
Official symbol Ccng2 [Rat]
Official name cyclin G2
Species Rat (Rattus norvegicus)
Entrez Gene ID 29157
Transcript(s) for this gene NM_001105725 (2506 bp), XM_001063045 (2409 bp), XM_223270 (2409 bp)
Official symbol FOS [Human]
Official name FBJ murine osteosarcoma viral oncogene homolog
Species Human (Homo sapiens)
Entrez Gene ID 2353
Transcript(s) for this gene NM_005252 (2158 bp), ENST00000556324, ENST00000303562, ENST00000535987, ENST00000554617, ENST00000555242, ENST00000555347, ENST00000555686
Official symbol Fos [Mouse]
Official name FBJ osteosarcoma oncogene
Species Mouse (Mus musculus)
Entrez Gene ID 14281
Transcript(s) for this gene NM_010234 (2107 bp), ENSMUST00000140525
Official symbol Fos [Rat]
Official name FBJ osteosarcoma oncogene
Species Rat (Rattus norvegicus)
Entrez Gene ID 314322
Transcript(s) for this gene NM_022197 (1589 bp), XM_234422 (1713 bp)
Official symbol PFKP [Human]
Official name phosphofructokinase, platelet
Species Human (Homo sapiens)
Entrez Gene ID 5214
Transcript(s) for this gene NM_001242339 (2781 bp), NM_002627 (2657 bp), ENST00000495715, XM_005252465 (2853 bp), XM_005252466 (2700 bp), XM_005252467 (2623 bp), XM_006717449 (2776 bp), ENST00000381072, ENST00000381075, ENST00000381125
Official symbol Pfkp [Mouse]
Official name phosphofructokinase, platelet
Species Mouse (Mus musculus)
Entrez Gene ID 56421
Transcript(s) for this gene NM_019703 (4033 bp), ENSMUST00000151894, NM_001291071 (4033 bp), XM_006516487 (2596 bp), XM_006516488 (8898 bp), XM_006516489 (1756 bp), XM_006516490 (8745 bp)
Official symbol Pfkp [Rat]
Official name phosphofructokinase, platelet
Species Rat (Rattus norvegicus)
Entrez Gene ID 60416
Transcript(s) for this gene NM_206847 (2712 bp), XM_008771885 (2750 bp)
Official symbol F3 [Human]
Official name coagulation factor III (thromboplastin, tissue factor)
Species Human (Homo sapiens)
Entrez Gene ID 2152
Transcript(s) for this gene NM_001178096 (2233 bp), NM_001993 (2393 bp), ENST00000480356, ENST00000334047, ENST00000370207
Official symbol F3 [Mouse]
Official name coagulation factor III
Species Mouse (Mus musculus)
Entrez Gene ID 14066
Transcript(s) for this gene NM_010171 (1876 bp)
Official symbol F3 [Rat]
Official name coagulation factor III (thromboplastin, tissue factor)
Species Rat (Rattus norvegicus)
Entrez Gene ID 25584
Transcript(s) for this gene NM_013057 (1798 bp)
Official symbol CA9 [Human]
Official name carbonic anhydrase IX
Species Human (Homo sapiens)
Entrez Gene ID 768
Transcript(s) for this gene NM_001216 (1561 bp), ENST00000493245, XM_006716866 (1587 bp), XM_006716867 (1645 bp), XM_006716868 (1473 bp), XM_006716869 (1012 bp), XM_006716870 (919 bp), ENST00000378357, ENST00000617161
Official symbol Car9 [Mouse]
Official name carbonic anhydrase 9
Species Mouse (Mus musculus)
Entrez Gene ID 230099
Transcript(s) for this gene NM_139305 (1959 bp), ENSMUST00000154251, ENSMUST00000129996, XM_006537831 (1898 bp)
Official symbol APEX1 [Human]
Official name APEX nuclease (multifunctional DNA repair enzyme) 1
Species Human (Homo sapiens)
Entrez Gene ID 328
Transcript(s) for this gene NM_001244249 (1558 bp), NM_001641 (1563 bp), NM_080648 (1497 bp), NM_080649 (1507 bp), ENST00000557365, XM_005267581 (1505 bp), XM_005267582 (1542 bp), ENST00000216714, ENST00000398030, ENST00000555414, ENST00000557054
Official symbol Apex1 [Mouse]
Official name apurinic/apyrimidinic endonuclease 1
Species Mouse (Mus musculus)
Entrez Gene ID 11792
Transcript(s) for this gene NM_009687 (1307 bp), XM_006518456 (1268 bp)
Official symbol Apex1 [Rat]
Official name APEX nuclease (multifunctional DNA repair enzyme) 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 79116
Transcript(s) for this gene NM_024148 (1213 bp), XM_006251913 (1258 bp)
Official symbol VEGFA [Human]
Official name vascular endothelial growth factor A
Species Human (Homo sapiens)
Entrez Gene ID 7422
Transcript(s) for this gene NM_001025366 (3677 bp), NM_001025367 (3608 bp), NM_001025368 (3554 bp), NM_001025369 (3519 bp), NM_001025370 (3422 bp), NM_001033756 (3488 bp), NM_001171622 (3392 bp), NM_001171623 (3677 bp), NM_001171624 (3626 bp), NM_001171625 (3608 bp), NM_001171626 (3554 bp), NM_001171627 (3519 bp), NM_001171628 (3422 bp), NM_001171629 (3488 bp), NM_001171630 (3392 bp), NM_001204384 (3494 bp), NM_001204385 (3494 bp), NM_003376 (3626 bp), ENST00000518538, NM_001287044 (2569 bp), ENST00000230480, ENST00000324450, ENST00000372055, ENST00000372064, ENST00000372067, ENST00000372077, ENST00000413642, ENST00000417285, ENST00000425836, ENST00000457104, ENST00000482630, ENST00000518689, ENST00000518824, ENST00000520948, ENST00000523125, ENST00000523873, ENST00000523950, ENST00000611736, ENST00000615393, ENST00000617771, ENST00000621747
Official symbol Vegfa [Mouse]
Official name vascular endothelial growth factor A
Species Mouse (Mus musculus)
Entrez Gene ID 22339
Transcript(s) for this gene NM_001025250 (3547 bp), NM_001025257 (3343 bp), NM_001110266 (2857 bp), NM_001110267 (2785 bp), NM_001110268 (2653 bp), NM_009505 (3475 bp), ENSMUST00000150327, NM_001287056 (3547 bp), NM_001287057 (3475 bp), NM_001287058 (3343 bp), NM_001317041 (3475 bp)
Official symbol Vegfa [Rat]
Official name vascular endothelial growth factor A
Species Rat (Rattus norvegicus)
Entrez Gene ID 83785
Transcript(s) for this gene NM_001110333 (3474 bp), NM_001110334 (3342 bp), NM_001110335 (2616 bp), NM_001110336 (2544 bp), NM_031836 (3546 bp), NM_001287107 (3546 bp), NM_001287108 (3474 bp), NM_001287110 (3342 bp), NM_001287111 (3414 bp), NM_001287112 (3414 bp), NM_001287113 (3425 bp), NM_001287114 (3293 bp), NR_105011 (0 bp)
Official symbol IER3 [Human]
Official name immediate early response 3
Species Human (Homo sapiens)
Entrez Gene ID 8870
Transcript(s) for this gene NM_003897 (1254 bp), NM_052815 (1345 bp), ENST00000259874, ENST00000376377
Official symbol Ier3 [Mouse]
Official name immediate early response 3
Species Mouse (Mus musculus)
Entrez Gene ID 15937
Transcript(s) for this gene NM_133662 (1090 bp)
Official symbol Ier3 [Rat]
Official name immediate early response 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 294235
Transcript(s) for this gene NM_212505 (1114 bp)
Official symbol PGK1 [Human]
Official name phosphoglycerate kinase 1
Species Human (Homo sapiens)
Entrez Gene ID 5230
Transcript(s) for this gene NM_000291 (2439 bp), ENST00000491291, ENST00000373316
Official symbol Pgk1 [Mouse]
Official name phosphoglycerate kinase 1
Species Mouse (Mus musculus)
Entrez Gene ID 18655
Transcript(s) for this gene NM_008828 (1840 bp), ENSMUST00000133559
Official symbol Pgk1 [Rat]
Official name phosphoglycerate kinase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24644
Transcript(s) for this gene NM_053291 (1685 bp)
Official symbol LOX [Human]
Official name lysyl oxidase
Species Human (Homo sapiens)
Entrez Gene ID 4015
Transcript(s) for this gene NM_001178102 (4393 bp), NM_002317 (5177 bp), ENST00000513319, ENST00000231004
Official symbol Lox [Mouse]
Official name lysyl oxidase
Species Mouse (Mus musculus)
Entrez Gene ID 16948
Transcript(s) for this gene NM_010728 (4914 bp), NM_001286181 (4537 bp), NM_001286182 (4494 bp)
Official symbol Lox [Rat]
Official name lysyl oxidase
Species Rat (Rattus norvegicus)
Entrez Gene ID 24914
Transcript(s) for this gene NM_017061 (1808 bp), XM_006254713 (4896 bp), XM_006254714 (4796 bp), XM_006254715 (1635 bp)
Official symbol HNF4A [Human]
Official name hepatocyte nuclear factor 4, alpha
Species Human (Homo sapiens)
Entrez Gene ID 3172
Transcript(s) for this gene NM_000457 (4737 bp), NM_001030003 (4528 bp), NM_001030004 (1449 bp), NM_175914 (4558 bp), NM_178849 (4707 bp), NM_178850 (1628 bp), NM_001258355 (4828 bp), NM_001287182 (4750 bp), NM_001287183 (4780 bp), NM_001287184 (1671 bp), XM_005260407 (4817 bp), ENST00000316099, ENST00000316673, ENST00000415691, ENST00000443598, ENST00000457232, ENST00000609795, ENST00000619550
Official symbol Hnf4a [Mouse]
Official name hepatic nuclear factor 4, alpha
Species Mouse (Mus musculus)
Entrez Gene ID 15378
Transcript(s) for this gene NM_008261 (4391 bp), ENSMUST00000131658, XM_006498787 (4356 bp), XM_006498788 (4305 bp), NM_001312906 (4393 bp), NM_001312907 (4363 bp), XM_011239305 (4312 bp), XM_011239306 (4282 bp)
Official symbol Hnf4a [Rat]
Official name hepatocyte nuclear factor 4, alpha
Species Rat (Rattus norvegicus)
Entrez Gene ID 25735
Transcript(s) for this gene NM_022180 (4416 bp), NM_001270931 (4456 bp), NM_001270933 (4426 bp), XM_006235515 (2811 bp), XM_006235516 (2751 bp)
Official symbol BNIP3L [Human]
Official name BCL2/adenovirus E1B 19kDa interacting protein 3-like
Species Human (Homo sapiens)
Entrez Gene ID 665
Transcript(s) for this gene NM_004331 (3505 bp), ENST00000521254, XM_005273617 (3405 bp), ENST00000380629, ENST00000518611, ENST00000520409, ENST00000523515, ENST00000620910, XM_011544630 (3354 bp)
Official symbol Bnip3l [Mouse]
Official name BCL2/adenovirus E1B interacting protein 3-like
Species Mouse (Mus musculus)
Entrez Gene ID 12177
Transcript(s) for this gene NM_009761 (3237 bp), ENSMUST00000151059, XM_006518471 (3154 bp), XM_011244936 (3298 bp)
Official symbol Bnip3l [Rat]
Official name BCL2/adenovirus E1B interacting protein 3-like
Species Rat (Rattus norvegicus)
Entrez Gene ID 140923
Transcript(s) for this gene NM_080888 (3219 bp), XM_006252091 (4997 bp), XM_008770733 (5126 bp), XM_008770734 (2676 bp)
Official symbol MET [Human]
Official name MET proto-oncogene, receptor tyrosine kinase
Species Human (Homo sapiens)
Entrez Gene ID 4233
Transcript(s) for this gene NM_000245 (6641 bp), NM_001127500 (6695 bp), ENST00000495962, XM_006715988 (6547 bp), XM_006715989 (6493 bp), XM_006715990 (5311 bp), XM_006715991 (5456 bp), ENST00000318493, ENST00000397752, ENST00000436117
Official symbol Met [Mouse]
Official name met proto-oncogene
Species Mouse (Mus musculus)
Entrez Gene ID 17295
Transcript(s) for this gene NM_008591 (6652 bp), ENSMUST00000145473, XM_006505002 (6729 bp), XM_011241042 (6761 bp), XM_011241043 (6438 bp)
Official symbol Met [Rat]
Official name MET proto-oncogene, receptor tyrosine kinase
Species Rat (Rattus norvegicus)
Entrez Gene ID 24553
Transcript(s) for this gene NM_031517 (4187 bp), XM_006236129 (6726 bp)
Official symbol BNIP3 [Human]
Official name BCL2/adenovirus E1B 19kDa interacting protein 3
Species Human (Homo sapiens)
Entrez Gene ID 664
Transcript(s) for this gene NM_004052 (1535 bp), ENST00000368636
Official symbol Bnip3 [Mouse]
Official name BCL2/adenovirus E1B interacting protein 3
Species Mouse (Mus musculus)
Entrez Gene ID 12176
Transcript(s) for this gene NM_009760 (1756 bp), ENSMUST00000148970
Official symbol Bnip3 [Rat]
Official name BCL2/adenovirus E1B interacting protein 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 84480
Transcript(s) for this gene NM_053420 (1641 bp)
Official symbol P4ha1 [Mouse]
Official name procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
Species Mouse (Mus musculus)
Entrez Gene ID 18451
Transcript(s) for this gene NM_011030 (4057 bp), XM_006513340 (3136 bp), XM_006513341 (1475 bp), XM_006513342 (1292 bp), NM_001316370 (3817 bp), NM_001316371 (4057 bp)
Official symbol P4HA1 [Human]
Official name prolyl 4-hydroxylase, alpha polypeptide I
Species Human (Homo sapiens)
Entrez Gene ID 5033
Transcript(s) for this gene NM_000917 (2860 bp), NM_001017962 (2860 bp), NM_001142595 (2953 bp), NM_001142596 (2806 bp), ENST00000464310, ENST00000263556, ENST00000307116, ENST00000373008, ENST00000394890, ENST00000440381
Official symbol Gpi1 [Mouse]
Official name glucose phosphate isomerase 1
Species Mouse (Mus musculus)
Entrez Gene ID 14751
Transcript(s) for this gene NM_008155 (2887 bp), XM_001004276 (1993 bp), XM_003689446 (1990 bp), ENSMUST00000138773, XM_006544528 (1198 bp)
Official symbol GPI [Human]
Official name glucose-6-phosphate isomerase
Species Human (Homo sapiens)
Entrez Gene ID 2821
Transcript(s) for this gene NM_000175 (4212 bp), NM_001184722 (4275 bp), ENST00000590362, NM_001289789 (4356 bp), NM_001289790 (4125 bp), XM_005258764 (2088 bp), XM_006723148 (2027 bp), XM_005258763 (2269 bp), ENST00000356487, ENST00000415930, ENST00000586425
Official symbol Gpi [Rat]
Official name glucose-6-phosphate isomerase
Species Rat (Rattus norvegicus)
Entrez Gene ID 292804
Transcript(s) for this gene NM_207592 (2130 bp)
Official symbol Mif [Mouse]
Official name macrophage migration inhibitory factor
Species Mouse (Mus musculus)
Entrez Gene ID 17319
Transcript(s) for this gene NM_010798 (554 bp)
Official symbol MIF [Human]
Official name macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Species Human (Homo sapiens)
Entrez Gene ID 4282
Transcript(s) for this gene NM_002415 (561 bp), ENST00000498385, ENST00000215754
Official symbol Mif [Rat]
Official name macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Species Rat (Rattus norvegicus)
Entrez Gene ID 81683
Transcript(s) for this gene NM_031051 (551 bp)
Official symbol Hif1a [Mouse]
Official name hypoxia inducible factor 1, alpha subunit
Species Mouse (Mus musculus)
Entrez Gene ID 15251
Transcript(s) for this gene NM_010431 (4775 bp), ENSMUST00000157041, XM_006515477 (4747 bp), XM_006515478 (4706 bp), NM_001313919 (4788 bp), NM_001313920 (4436 bp), XM_011243996 (4473 bp), XM_011243997 (4431 bp), XM_017314961 (0 bp)
Official symbol HIF1A [Human]
Official name hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Species Human (Homo sapiens)
Entrez Gene ID 3091
Transcript(s) for this gene NM_001243084 (3979 bp), NM_001530 (4082 bp), NM_181054 (3955 bp), ENST00000557446, ENST00000553999, ENST00000323441, ENST00000337138, ENST00000394997, ENST00000539097, ENST00000557538
Official symbol Hif1a [Rat]
Official name hypoxia inducible factor 1 alpha subunit
Species Rat (Rattus norvegicus)
Entrez Gene ID 29560
Transcript(s) for this gene NM_024359 (3718 bp), XM_006240196 (4276 bp), XM_006240197 (4273 bp), XM_006240198 (4266 bp), XM_006240199 (3975 bp), XM_008764695 (4060 bp)
Official symbol Eif4ebp1 [Mouse]
Official name eukaryotic translation initiation factor 4E binding protein 1
Species Mouse (Mus musculus)
Entrez Gene ID 13685
Transcript(s) for this gene NM_007918 (981 bp)
Official symbol EIF4EBP1 [Human]
Official name eukaryotic translation initiation factor 4E binding protein 1
Species Human (Homo sapiens)
Entrez Gene ID 1978
Transcript(s) for this gene NM_004095 (877 bp), ENST00000520657, ENST00000338825
Official symbol Eif4ebp1 [Rat]
Official name eukaryotic translation initiation factor 4E binding protein 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 116636
Transcript(s) for this gene NM_053857 (862 bp)
Official symbol Blm [Mouse]
Official name Bloom syndrome, RecQ helicase-like
Species Mouse (Mus musculus)
Entrez Gene ID 12144
Transcript(s) for this gene NM_001042527 (4598 bp), NM_007550 (4869 bp)
Official symbol BLM [Human]
Official name Bloom syndrome, RecQ helicase-like
Species Human (Homo sapiens)
Entrez Gene ID 641
Transcript(s) for this gene NM_000057 (4555 bp), ENST00000560821, NM_001287246 (4665 bp), NM_001287247 (4162 bp), NM_001287248 (4721 bp), XM_006720632 (2611 bp), ENST00000355112, ENST00000560509
Official symbol Blm [Rat]
Official name Bloom syndrome, RecQ helicase-like
Species Rat (Rattus norvegicus)
Entrez Gene ID 308755
Transcript(s) for this gene NM_001107526 (4977 bp), XM_001066539 (4530 bp), XM_218837 (4530 bp), XM_003748888 (4768 bp), XM_003753301 (4768 bp), XM_006223359 (4771 bp), XM_006229458 (4771 bp), XM_008759588 (4805 bp), XM_008759589 (4801 bp), XM_008759590 (4546 bp), XM_008759591 (3792 bp), XM_008774594 (4805 bp), XM_008774595 (4801 bp), XM_008774596 (4546 bp), XM_008774597 (3792 bp)
Official symbol Trp53 [Mouse]
Official name transformation related protein 53
Species Mouse (Mus musculus)
Entrez Gene ID 22059
Transcript(s) for this gene NM_001127233 (1877 bp), NM_011640 (1781 bp), ENSMUST00000147512, XM_006533157 (2157 bp), XM_006533158 (1843 bp)
Official symbol TP53 [Human]
Official name tumor protein p53
Species Human (Homo sapiens)
Entrez Gene ID 7157
Transcript(s) for this gene NM_000546 (2591 bp), NM_001126112 (2588 bp), NM_001126113 (2651 bp), NM_001126114 (2724 bp), NM_001126115 (2271 bp), NM_001126116 (2404 bp), NM_001126117 (2331 bp), NM_001126118 (2708 bp), NM_001276695 (2651 bp), NM_001276696 (2724 bp), NM_001276697 (2271 bp), NM_001276698 (2404 bp), NM_001276699 (2331 bp), NM_001276760 (2591 bp), NM_001276761 (2588 bp), ENST00000574684, ENST00000269305, ENST00000359597, ENST00000413465, ENST00000420246, ENST00000445888, ENST00000455263, ENST00000504290, ENST00000504937, ENST00000510385, ENST00000610292, ENST00000610538, ENST00000610623, ENST00000615910, ENST00000617185, ENST00000618944, ENST00000619186, ENST00000619485, ENST00000620739, ENST00000622645
Official symbol Tp53 [Rat]
Official name tumor protein p53
Species Rat (Rattus norvegicus)
Entrez Gene ID 24842
Transcript(s) for this gene NM_030989 (1792 bp), XM_006246594 (2185 bp), XM_006246595 (2542 bp), XM_008767773 (1321 bp)
Official symbol Vdac1 [Mouse]
Official name voltage-dependent anion channel 1
Species Mouse (Mus musculus)
Entrez Gene ID 22333
Transcript(s) for this gene NM_011694 (2036 bp), ENSMUST00000157052, XM_006533164 (1977 bp)
Official symbol VDAC1 [Human]
Official name voltage-dependent anion channel 1
Species Human (Homo sapiens)
Entrez Gene ID 7416
Transcript(s) for this gene NM_003374 (1993 bp), NR_036624 (2071 bp), NR_036625 (2074 bp), XM_005272075 (2206 bp), ENST00000265333, ENST00000395044, ENST00000395047
Official symbol Vdac1 [Rat]
Official name voltage-dependent anion channel 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 83529
Transcript(s) for this gene NM_031353 (1818 bp), XM_006246346 (1774 bp)
Official symbol Plau [Mouse]
Official name plasminogen activator, urokinase
Species Mouse (Mus musculus)
Entrez Gene ID 18792
Transcript(s) for this gene NM_008873 (2343 bp)
Official symbol PLAU [Human]
Official name plasminogen activator, urokinase
Species Human (Homo sapiens)
Entrez Gene ID 5328
Transcript(s) for this gene NM_001145031 (2680 bp), NM_002658 (2395 bp), ENST00000496926, XM_006717893 (2309 bp), ENST00000372764, ENST00000446342
Official symbol Plau [Rat]
Official name plasminogen activator, urokinase
Species Rat (Rattus norvegicus)
Entrez Gene ID 25619
Transcript(s) for this gene NM_013085 (2355 bp)
Official symbol Pgf [Mouse]
Official name placental growth factor
Species Mouse (Mus musculus)
Entrez Gene ID 18654
Transcript(s) for this gene NM_008827 (1599 bp), NM_001271705 (1266 bp), XM_006515583 (2241 bp), XM_006515584 (2221 bp), XM_006515585 (2096 bp), XM_011244015 (1299 bp), XM_011244016 (2043 bp)
Official symbol PGF [Human]
Official name placental growth factor
Species Human (Homo sapiens)
Entrez Gene ID 5228
Transcript(s) for this gene NM_001207012 (1848 bp), NM_002632 (1911 bp), ENST00000557748, NM_001293643 (1908 bp), XM_005267761 (1755 bp), ENST00000238607, ENST00000405431, ENST00000553716, ENST00000555567
Official symbol Pgf [Rat]
Official name placental growth factor
Species Rat (Rattus norvegicus)
Entrez Gene ID 94203
Transcript(s) for this gene NM_053595 (1586 bp)
Official symbol Map3k1 [Mouse]
Official name mitogen-activated protein kinase kinase kinase 1
Species Mouse (Mus musculus)
Entrez Gene ID 26401
Transcript(s) for this gene NM_011945 (6963 bp), ENSMUST00000175936, XM_006517664 (6477 bp), XM_006517665 (6455 bp), XM_006517666 (9638 bp), XM_006517667 (6922 bp), XM_011244663 (6942 bp), XM_011244664 (9832 bp)
Official symbol MAP3K1 [Human]
Official name mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
Species Human (Homo sapiens)
Entrez Gene ID 4214
Transcript(s) for this gene NM_005921 (7522 bp), XM_001128827 (7793 bp), XM_042066 (7719 bp), ENST00000469188, XM_005248519 (6790 bp), XM_005248520 (6585 bp), ENST00000399503
Official symbol Map3k1 [Rat]
Official name mitogen activated protein kinase kinase kinase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 116667
Transcript(s) for this gene NM_053887 (5180 bp), XM_001074670 (5154 bp)
Official symbol Adm [Mouse]
Official name adrenomedullin
Species Mouse (Mus musculus)
Entrez Gene ID 11535
Transcript(s) for this gene NM_009627 (1381 bp)
Official symbol ADM [Human]
Official name adrenomedullin
Species Human (Homo sapiens)
Entrez Gene ID 133
Transcript(s) for this gene NM_001124 (1606 bp), ENST00000278175, ENST00000524948, ENST00000525063, ENST00000526492, ENST00000528544, ENST00000528655, ENST00000530439, ENST00000534464
Official symbol Adm [Rat]
Official name adrenomedullin
Species Rat (Rattus norvegicus)
Entrez Gene ID 25026
Transcript(s) for this gene NM_012715 (1395 bp), XM_008759687 (2895 bp)
Official symbol Tpi1 [Mouse]
Official name triosephosphate isomerase 1
Species Mouse (Mus musculus)
Entrez Gene ID 21991
Transcript(s) for this gene NM_009415 (1601 bp), ENSMUST00000154883
Official symbol TPI1 [Human]
Official name triosephosphate isomerase 1
Species Human (Homo sapiens)
Entrez Gene ID 7167
Transcript(s) for this gene NM_000365 (1366 bp), NM_001159287 (1460 bp), NR_027483 (1602 bp), NM_001258026 (1602 bp), ENST00000482209, ENST00000229270, ENST00000396705, ENST00000488464, ENST00000535434, ENST00000613953
Official symbol Tpi1 [Rat]
Official name triosephosphate isomerase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24849
Transcript(s) for this gene NM_022922 (1471 bp)
Official symbol P4hb [Mouse]
Official name prolyl 4-hydroxylase, beta polypeptide
Species Mouse (Mus musculus)
Entrez Gene ID 18453
Transcript(s) for this gene NM_011032 (2538 bp), ENSMUST00000166620
Official symbol P4HB [Human]
Official name prolyl 4-hydroxylase subunit beta
Species Human (Homo sapiens)
Entrez Gene ID 5034
Transcript(s) for this gene NM_000918 (2596 bp), ENST00000574007, ENST00000331483, ENST00000439918, ENST00000576390
Official symbol P4hb [Rat]
Official name prolyl 4-hydroxylase, beta polypeptide
Species Rat (Rattus norvegicus)
Entrez Gene ID 25506
Transcript(s) for this gene NM_012998 (2460 bp)
Official symbol Jmjd6 [Mouse]
Official name jumonji domain containing 6
Species Mouse (Mus musculus)
Entrez Gene ID 107817
Transcript(s) for this gene NM_033398 (1688 bp), ENSMUST00000141735, ENSMUST00000130120, XM_006531960 (1625 bp), XR_388319 (0 bp), XR_388320 (0 bp)
Official symbol JMJD6 [Human]
Official name jumonji domain containing 6
Species Human (Homo sapiens)
Entrez Gene ID 23210
Transcript(s) for this gene NM_001081461 (5445 bp), NM_015167 (1834 bp), ENST00000591460, ENST00000397625, ENST00000445478, ENST00000585429, ENST00000617192
Official symbol Mxi1 [Mouse]
Official name MAX interactor 1, dimerization protein
Species Mouse (Mus musculus)
Entrez Gene ID 17859
Transcript(s) for this gene NM_001008542 (5156 bp), NM_001008543 (4843 bp), NM_010847 (4996 bp), XM_006526735 (2705 bp), XM_006526736 (2268 bp), XM_006526737 (2570 bp), XM_006526738 (2195 bp), XM_006526739 (2402 bp), XM_006526740 (2521 bp), XM_006526741 (2307 bp), XM_006526742 (2276 bp)
Official symbol MXI1 [Human]
Official name MAX interactor 1, dimerization protein
Species Human (Homo sapiens)
Entrez Gene ID 4601
Transcript(s) for this gene NM_001008541 (3047 bp), NM_005962 (3272 bp), NM_130439 (3470 bp), ENST00000485566, ENST00000484030, ENST00000239007, ENST00000332674, ENST00000361248, ENST00000369612, ENST00000393134
Official symbol Mxi1 [Rat]
Official name MAX interactor 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 25701
Transcript(s) for this gene NM_013160 (2303 bp), XM_006231604 (2837 bp), XM_006231605 (2249 bp), XM_006231606 (2408 bp)
Official symbol Ddit4 [Mouse]
Official name DNA-damage-inducible transcript 4
Species Mouse (Mus musculus)
Entrez Gene ID 74747
Transcript(s) for this gene NM_029083 (1685 bp)
Official symbol DDIT4 [Human]
Official name DNA damage inducible transcript 4
Species Human (Homo sapiens)
Entrez Gene ID 54541
Transcript(s) for this gene NM_019058 (1752 bp), ENST00000473155, ENST00000307365
Official symbol Ddit4 [Rat]
Official name DNA-damage-inducible transcript 4
Species Rat (Rattus norvegicus)
Entrez Gene ID 140942
Transcript(s) for this gene NM_080906 (1749 bp)
Official symbol Bhlhe40 [Mouse]
Official name basic helix-loop-helix family, member e40
Species Mouse (Mus musculus)
Entrez Gene ID 20893
Transcript(s) for this gene NM_011498 (3113 bp), ENSMUST00000166346
Official symbol BHLHE40 [Human]
Official name basic helix-loop-helix family, member e40
Species Human (Homo sapiens)
Entrez Gene ID 8553
Transcript(s) for this gene NM_003670 (3061 bp), ENST00000467610, ENST00000256495
Official symbol Bhlhe40 [Rat]
Official name basic helix-loop-helix family, member e40
Species Rat (Rattus norvegicus)
Entrez Gene ID 79431
Transcript(s) for this gene NM_053328 (2388 bp)
Official symbol Mmp9 [Mouse]
Official name matrix metallopeptidase 9
Species Mouse (Mus musculus)
Entrez Gene ID 17395
Transcript(s) for this gene NM_013599 (3189 bp), ENSMUST00000144917, XM_006498861 (3220 bp)
Official symbol MMP9 [Human]
Official name matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
Species Human (Homo sapiens)
Entrez Gene ID 4318
Transcript(s) for this gene NM_004994 (2387 bp), ENST00000372330
Official symbol Mmp9 [Rat]
Official name matrix metallopeptidase 9
Species Rat (Rattus norvegicus)
Entrez Gene ID 81687
Transcript(s) for this gene NM_031055 (2986 bp)
Official symbol Pdk1 [Mouse]
Official name pyruvate dehydrogenase kinase, isoenzyme 1
Species Mouse (Mus musculus)
Entrez Gene ID 228026
Transcript(s) for this gene NM_172665 (5202 bp), ENSMUST00000156036, XM_006499197 (5291 bp), XM_006499198 (5206 bp), XM_011239444 (5291 bp), XM_011239445 (5412 bp), XM_011239446 (5317 bp)
Official symbol Pfkfb3 [Mouse]
Official name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Species Mouse (Mus musculus)
Entrez Gene ID 170768
Transcript(s) for this gene NM_001177752 (4869 bp), NM_001177753 (5206 bp), NM_001177754 (5066 bp), NM_001177755 (5130 bp), NM_001177756 (5153 bp), NM_001177757 (5119 bp), NM_001177758 (4680 bp), NM_133232 (5043 bp), NM_172976 (1736 bp), ENSMUST00000155167, XM_006497367 (4566 bp), XM_006497368 (4344 bp), XM_006497369 (5078 bp), XM_006497370 (4232 bp)
Official symbol PFKFB3 [Human]
Official name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Species Human (Homo sapiens)
Entrez Gene ID 5209
Transcript(s) for this gene NM_001145443 (4224 bp), NM_004566 (4553 bp), ENST00000487989, NM_001282630 (4271 bp), XM_005252463 (4560 bp), XM_005252464 (4363 bp), ENST00000317350, ENST00000360521, ENST00000379775, ENST00000379785, ENST00000379789, ENST00000536985, ENST00000625260, ENST00000626882
Official symbol Pfkfb3 [Rat]
Official name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 117276
Transcript(s) for this gene NM_057135 (2148 bp), XM_006254192 (5173 bp), XM_006254193 (5196 bp), XM_006254195 (3917 bp), XM_006254196 (2650 bp), XM_006254197 (5085 bp), XM_006254198 (5108 bp), XM_008771850 (4004 bp), XM_008771851 (4200 bp)
Official symbol Slc2a1 [Mouse]
Official name solute carrier family 2 (facilitated glucose transporter), member 1
Species Mouse (Mus musculus)
Entrez Gene ID 20525
Transcript(s) for this gene NM_011400 (2573 bp), XM_006502908 (2454 bp)
Official symbol SLC2A1 [Human]
Official name solute carrier family 2 (facilitated glucose transporter), member 1
Species Human (Homo sapiens)
Entrez Gene ID 6513
Transcript(s) for this gene NM_006516 (3687 bp), ENST00000475162, ENST00000426263
Official symbol Slc2a1 [Rat]
Official name solute carrier family 2 (facilitated glucose transporter), member 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24778
Transcript(s) for this gene NM_138827 (2571 bp)
Official symbol Gbe1 [Mouse]
Official name glucan (1,4-alpha-), branching enzyme 1
Species Mouse (Mus musculus)
Entrez Gene ID 74185
Transcript(s) for this gene NM_028803 (2988 bp), ENSMUST00000169432
Official symbol GBE1 [Human]
Official name glucan (1,4-alpha-), branching enzyme 1
Species Human (Homo sapiens)
Entrez Gene ID 2632
Transcript(s) for this gene NM_000158 (3118 bp), ENST00000498468, ENST00000429644, ENST00000489715
Official symbol Per1 [Mouse]
Official name period circadian clock 1
Species Mouse (Mus musculus)
Entrez Gene ID 18626
Transcript(s) for this gene NM_001159367 (4648 bp), NM_011065 (4663 bp), XM_006532480 (4779 bp), XM_006532481 (6064 bp), XM_006532482 (5152 bp)
Official symbol PER1 [Human]
Official name period circadian clock 1
Species Human (Homo sapiens)
Entrez Gene ID 5187
Transcript(s) for this gene NM_002616 (4717 bp), ENST00000585284, XM_005256689 (4709 bp), XM_005256690 (4529 bp), ENST00000317276, ENST00000354903, ENST00000581082
Official symbol Per1 [Rat]
Official name period circadian clock 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 287422
Transcript(s) for this gene NM_001034125 (4001 bp), XM_340822 (3870 bp), XM_006246613 (4785 bp), XM_006246614 (8435 bp)
Official symbol Ctsa [Mouse]
Official name cathepsin A
Species Mouse (Mus musculus)
Entrez Gene ID 19025
Transcript(s) for this gene NM_001038492 (3548 bp), NM_008906 (3301 bp), ENSMUST00000155061, XM_011239360 (1988 bp)
Official symbol CTSA [Human]
Official name cathepsin A
Species Human (Homo sapiens)
Entrez Gene ID 5476
Transcript(s) for this gene NM_000308 (3062 bp), NM_001127695 (3108 bp), NM_001167594 (3011 bp), ENST00000607841, ENST00000191018, ENST00000354880, ENST00000372459, ENST00000372484
Official symbol Ctsa [Rat]
Official name cathepsin A
Species Rat (Rattus norvegicus)
Entrez Gene ID 296370
Transcript(s) for this gene NM_001011959 (2292 bp), XM_215920 (1518 bp), XM_006235534 (2205 bp)
Official symbol Slc16a3 [Mouse]
Official name solute carrier family 16 (monocarboxylic acid transporters), member 3
Species Mouse (Mus musculus)
Entrez Gene ID 80879
Transcript(s) for this gene NM_001038653 (2481 bp), NM_001038654 (2386 bp), NM_030696 (2493 bp), ENSMUST00000140467, XM_011249321 (2339 bp), XM_011249322 (2991 bp)
Official symbol SLC16A3 [Human]
Official name solute carrier family 16 member 3
Species Human (Homo sapiens)
Entrez Gene ID 9123
Transcript(s) for this gene NM_001042422 (2086 bp), NM_001042423 (2090 bp), NM_001206950 (2102 bp), NM_001206951 (2064 bp), NM_001206952 (2031 bp), NM_004207 (2058 bp), ENST00000584781, ENST00000392339, ENST00000392341, ENST00000581287, ENST00000582743, ENST00000617373, ENST00000619321, XM_011523607 (3953 bp)
Official symbol Slc16a3 [Rat]
Official name solute carrier family 16 member 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 80878
Transcript(s) for this gene NM_030834 (2118 bp), XM_006247931 (2235 bp), XM_006247932 (2527 bp), XM_006247933 (2142 bp), XM_006247934 (2201 bp), XM_008768513 (4959 bp), XM_008768514 (4866 bp)
Official symbol Ndrg1 [Mouse]
Official name N-myc downstream regulated gene 1
Species Mouse (Mus musculus)
Entrez Gene ID 17988
Transcript(s) for this gene NM_008681 (2909 bp), NM_010884 (2905 bp), ENSMUST00000171569, XM_006520568 (2807 bp)
Official symbol NDRG1 [Human]
Official name N-myc downstream regulated 1
Species Human (Homo sapiens)
Entrez Gene ID 10397
Transcript(s) for this gene NM_001135242 (3520 bp), NM_006096 (3123 bp), NM_001258432 (3006 bp), NM_001258433 (3017 bp), ENST00000523931, ENST00000323851, ENST00000414097, ENST00000518066, ENST00000518176, ENST00000522476, ENST00000537882
Official symbol Ndrg1 [Rat]
Official name N-myc downstream regulated 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 299923
Transcript(s) for this gene NM_001011991 (2906 bp), XM_216923 (1287 bp), XM_006241708 (3151 bp)
Official symbol Igfbp3 [Mouse]
Official name insulin-like growth factor binding protein 3
Species Mouse (Mus musculus)
Entrez Gene ID 16009
Transcript(s) for this gene NM_008343 (2456 bp), XM_001001532 (1486 bp), XM_990107 (1339 bp), XM_011243665 (2359 bp)
Official symbol IGFBP3 [Human]
Official name insulin-like growth factor binding protein 3
Species Human (Homo sapiens)
Entrez Gene ID 3486
Transcript(s) for this gene NM_000598 (2620 bp), NM_001013398 (2638 bp), ENST00000465642, ENST00000275521, ENST00000381083, ENST00000381086, ENST00000613132, ENST00000615754
Official symbol Igfbp3 [Rat]
Official name insulin-like growth factor binding protein 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 24484
Transcript(s) for this gene NM_012588 (2416 bp), XM_001053435 (2291 bp)
Official symbol Egln2 [Mouse]
Official name egl-9 family hypoxia-inducible factor 2
Species Mouse (Mus musculus)
Entrez Gene ID 112406
Transcript(s) for this gene NM_053208 (2124 bp), ENSMUST00000152021, XM_006539473 (1569 bp), XM_006539474 (1178 bp)
Official symbol EGLN2 [Human]
Official name egl-9 family hypoxia inducible factor 2
Species Human (Homo sapiens)
Entrez Gene ID 112398
Transcript(s) for this gene NM_017555 (3928 bp), NM_053046 (2264 bp), NM_080732 (2174 bp), ENST00000602166, ENST00000599579, ENST00000594136, ENST00000303961, ENST00000406058, ENST00000593726, ENST00000594140
Official symbol Egln2 [Rat]
Official name egl-9 family hypoxia-inducible factor 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 308457
Transcript(s) for this gene NM_001004083 (2013 bp), XM_006228574 (1998 bp), XM_006228575 (2037 bp)
Official symbol Pfkl [Rat]
Official name phosphofructokinase, liver
Species Rat (Rattus norvegicus)
Entrez Gene ID 25741
Transcript(s) for this gene NM_013190 (2770 bp), XM_001079376 (2735 bp), XM_008772798 (2853 bp)
Official symbol PFKL [Human]
Official name phosphofructokinase, liver
Species Human (Homo sapiens)
Entrez Gene ID 5211
Transcript(s) for this gene NM_001002021 (3412 bp), NM_002626 (2934 bp), NR_024108 (3401 bp), XM_005261135 (2971 bp), XM_005261136 (2922 bp), XM_005261137 (2985 bp), XM_006724011 (3419 bp), XM_006724012 (3135 bp), ENST00000349048, ENST00000628044
Official symbol Pfkl [Mouse]
Official name phosphofructokinase, liver, B-type
Species Mouse (Mus musculus)
Entrez Gene ID 18641
Transcript(s) for this gene NM_008826 (3741 bp), ENSMUST00000149271
Official symbol P4ha1 [Rat]
Official name prolyl 4-hydroxylase, alpha polypeptide I
Species Rat (Rattus norvegicus)
Entrez Gene ID 64475
Transcript(s) for this gene NM_172062 (2145 bp), XM_006256424 (2816 bp), XM_006256425 (2725 bp)
Official symbol Ruvbl2 [Rat]
Official name RuvB-like AAA ATPase 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 292907
Transcript(s) for this gene NM_001025405 (1710 bp), XM_214951 (1493 bp), XM_006229029 (1915 bp)
Official symbol RUVBL2 [Human]
Official name RuvB-like AAA ATPase 2
Species Human (Homo sapiens)
Entrez Gene ID 10856
Transcript(s) for this gene NM_006666 (1488 bp), ENST00000598768, XM_005258426 (1956 bp), XM_005258427 (1560 bp), XM_005258428 (1886 bp), ENST00000595090, ENST00000601968, ENST00000627972
Official symbol Ruvbl2 [Mouse]
Official name RuvB-like protein 2
Species Mouse (Mus musculus)
Entrez Gene ID 20174
Transcript(s) for this gene NM_011304 (1675 bp), XM_006540722 (1654 bp), XM_006540723 (1859 bp)
Official symbol Hmox1 [Rat]
Official name heme oxygenase (decycling) 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24451
Transcript(s) for this gene NM_012580 (1600 bp)
Official symbol HMOX1 [Human]
Official name heme oxygenase (decycling) 1
Species Human (Homo sapiens)
Entrez Gene ID 3162
Transcript(s) for this gene NM_002133 (1606 bp), ENST00000494998, ENST00000216117
Official symbol Hmox1 [Mouse]
Official name heme oxygenase 1
Species Mouse (Mus musculus)
Entrez Gene ID 15368
Transcript(s) for this gene NM_010442 (1634 bp), ENSMUST00000160341
Official symbol Pgam1 [Rat]
Official name phosphoglycerate mutase 1 (brain)
Species Rat (Rattus norvegicus)
Entrez Gene ID 24642
Transcript(s) for this gene NM_053290 (1754 bp), XM_001053034 (1744 bp)
Official symbol Txnip [Rat]
Official name thioredoxin interacting protein
Species Rat (Rattus norvegicus)
Entrez Gene ID 117514
Transcript(s) for this gene NM_001008767 (2771 bp)
Official symbol TXNIP [Human]
Official name thioredoxin interacting protein
Species Human (Homo sapiens)
Entrez Gene ID 10628
Transcript(s) for this gene NM_006472 (2979 bp), ENST00000488537, ENST00000425134, ENST00000582401
Official symbol Txnip [Mouse]
Official name thioredoxin interacting protein
Species Mouse (Mus musculus)
Entrez Gene ID 56338
Transcript(s) for this gene NM_001009935 (2801 bp), NM_023719 (2798 bp), ENSMUST00000151832
Official symbol Nfkb1 [Rat]
Official name nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 81736
Transcript(s) for this gene XM_001075876 (3723 bp), XM_342346 (4088 bp), NM_001276711 (3956 bp), XM_006233358 (3612 bp), XM_006233360 (3434 bp)
Official symbol NFKB1 [Human]
Official name nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Species Human (Homo sapiens)
Entrez Gene ID 4790
Transcript(s) for this gene NM_001165412 (4090 bp), NM_003998 (4093 bp), ENST00000513803, XM_005263029 (4007 bp), XM_006714229 (3642 bp), ENST00000226574, ENST00000394820, ENST00000505458, ENST00000600343
Official symbol Nfkb1 [Mouse]
Official name nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Species Mouse (Mus musculus)
Entrez Gene ID 18033
Transcript(s) for this gene NM_008689 (4128 bp), ENSMUST00000150007, XM_006501105 (3394 bp), XM_006501106 (3618 bp), XM_006501107 (3808 bp)
Official symbol Edn1 [Rat]
Official name endothelin 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24323
Transcript(s) for this gene NM_012548 (1390 bp)
Official symbol EDN1 [Human]
Official name endothelin 1
Species Human (Homo sapiens)
Entrez Gene ID 1906
Transcript(s) for this gene NM_001168319 (2109 bp), NM_001955 (2112 bp), ENST00000379375
Official symbol Edn1 [Mouse]
Official name endothelin 1
Species Mouse (Mus musculus)
Entrez Gene ID 13614
Transcript(s) for this gene NM_010104 (2143 bp)
Official symbol Arnt [Rat]
Official name aryl hydrocarbon receptor nuclear translocator
Species Rat (Rattus norvegicus)
Entrez Gene ID 25242
Transcript(s) for this gene NM_012780 (2431 bp), XM_006232850 (2897 bp), XM_006232852 (2987 bp), XM_006232853 (2852 bp), XM_008761280 (2894 bp), XM_008761281 (2849 bp)
Official symbol ARNT [Human]
Official name aryl hydrocarbon receptor nuclear translocator
Species Human (Homo sapiens)
Entrez Gene ID 405
Transcript(s) for this gene NM_001197325 (4855 bp), NM_001668 (4903 bp), NM_178426 (3563 bp), NM_178427 (4858 bp), ENST00000512296, NM_001286035 (4944 bp), NM_001286036 (4897 bp), XM_005245151 (4818 bp), XM_005245153 (4806 bp), XM_005245154 (4670 bp), XM_005245157 (4710 bp), ENST00000354396, ENST00000358595, ENST00000505755, ENST00000515192
Official symbol Arnt [Mouse]
Official name aryl hydrocarbon receptor nuclear translocator
Species Mouse (Mus musculus)
Entrez Gene ID 11863
Transcript(s) for this gene NM_001037737 (4370 bp), NM_009709 (4325 bp), ENSMUST00000156653, XM_006500930 (4382 bp), XM_006500931 (4337 bp), XM_006500932 (1998 bp), XM_006500933 (1479 bp), XM_011239998 (4128 bp)
Official symbol Pdk1 [Rat]
Official name pyruvate dehydrogenase kinase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 116551
Transcript(s) for this gene NM_053826 (1609 bp), XM_001059583 (1026 bp), XM_001059645 (1305 bp), XM_006234352 (4817 bp)
Official symbol PDK1 [Human]
Official name pyruvate dehydrogenase kinase, isozyme 1
Species Human (Homo sapiens)
Entrez Gene ID 5163
Transcript(s) for this gene NM_002610 (4674 bp), NM_001278549 (4734 bp), XM_006712594 (1786 bp), XM_006712595 (3735 bp), ENST00000282077, ENST00000392571, ENST00000410055
Official symbol Cops5 [Rat]
Official name COP9 signalosome subunit 5
Species Rat (Rattus norvegicus)
Entrez Gene ID 312916
Transcript(s) for this gene NM_001025695 (1296 bp), XM_232615 (1271 bp), XM_006237758 (1213 bp)
Official symbol COPS5 [Human]
Official name COP9 signalosome subunit 5
Species Human (Homo sapiens)
Entrez Gene ID 10987
Transcript(s) for this gene NM_006837 (1510 bp), ENST00000523086, ENST00000357849, ENST00000517736
Official symbol Cops5 [Mouse]
Official name COP9 signalosome subunit 5
Species Mouse (Mus musculus)
Entrez Gene ID 26754
Transcript(s) for this gene NM_013715 (1731 bp), NM_001277101 (1482 bp)
Official symbol Lgals3 [Rat]
Official name lectin, galactoside-binding, soluble, 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 83781
Transcript(s) for this gene NM_031832 (948 bp)
Official symbol LGALS3 [Human]
Official name lectin, galactoside-binding, soluble, 3
Species Human (Homo sapiens)
Entrez Gene ID 3958
Transcript(s) for this gene NM_001177388 (744 bp), NM_002306 (1017 bp), NM_194327 (1947 bp), NR_003225 (1973 bp), ENST00000556438, ENST00000254301, ENST00000554715
Official symbol Lgals3 [Mouse]
Official name lectin, galactose binding, soluble 3
Species Mouse (Mus musculus)
Entrez Gene ID 16854
Transcript(s) for this gene NM_001145953 (1406 bp), NM_010705 (1379 bp)
Official symbol Odc1 [Rat]
Official name ornithine decarboxylase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24609
Transcript(s) for this gene NM_012615 (2423 bp), NM_001302083 (2393 bp), XM_006239907 (2457 bp), XM_006239908 (2373 bp), XM_006239906 (0 bp)
Official symbol Odc1 [Mouse]
Official name ornithine decarboxylase, structural 1
Species Mouse (Mus musculus)
Entrez Gene ID 18263
Transcript(s) for this gene NM_013614 (2547 bp)
Official symbol Nampt [Rat]
Official name nicotinamide phosphoribosyltransferase
Species Rat (Rattus norvegicus)
Entrez Gene ID 297508
Transcript(s) for this gene NM_177928 (2590 bp)
Official symbol Btg1 [Rat]
Official name B-cell translocation gene 1, anti-proliferative
Species Rat (Rattus norvegicus)
Entrez Gene ID 29618
Transcript(s) for this gene NM_017258 (1464 bp)
Official symbol BTG1 [Human]
Official name B-cell translocation gene 1, anti-proliferative
Species Human (Homo sapiens)
Entrez Gene ID 694
Transcript(s) for this gene NM_001731 (4704 bp), ENST00000256015
Official symbol Btg1 [Mouse]
Official name B cell translocation gene 1, anti-proliferative
Species Mouse (Mus musculus)
Entrez Gene ID 12226
Transcript(s) for this gene NM_007569 (5010 bp)
Official symbol Pkm [Rat]
Official name pyruvate kinase, muscle
Species Rat (Rattus norvegicus)
Entrez Gene ID 25630
Transcript(s) for this gene NM_053297 (1971 bp), XM_006243187 (2433 bp), XM_006243188 (2433 bp), XM_006243190 (2505 bp)
Official symbol PKM [Human]
Official name pyruvate kinase, muscle
Species Human (Homo sapiens)
Entrez Gene ID 5315
Transcript(s) for this gene NM_001206796 (2853 bp), NM_001206797 (2294 bp), NM_001206798 (2541 bp), NM_001206799 (2421 bp), NM_002654 (2516 bp), NM_182470 (2732 bp), NM_182471 (2516 bp), ENST00000570166, XM_005254443 (2463 bp), XM_005254445 (2725 bp), XM_006720570 (2560 bp), ENST00000319622, ENST00000335181, ENST00000389093, ENST00000449901, ENST00000565154, ENST00000565184, ENST00000568459, ENST00000568883
Official symbol Eno1 [Rat]
Official name enolase 1, (alpha)
Species Rat (Rattus norvegicus)
Entrez Gene ID 24333
Transcript(s) for this gene NM_001109908 (1803 bp), NM_012554 (1754 bp), XM_006239444 (1750 bp)
Official symbol ENO1 [Human]
Official name enolase 1, (alpha)
Species Human (Homo sapiens)
Entrez Gene ID 2023
Transcript(s) for this gene NM_001201483 (2567 bp), NM_001428 (2204 bp), ENST00000492343, XM_006710433 (1815 bp), ENST00000234590
Official symbol Eno1 [Mouse]
Official name enolase 1, alpha non-neuron
Species Mouse (Mus musculus)
Entrez Gene ID 13806
Transcript(s) for this gene NM_023119 (1831 bp), XM_001006583 (777 bp), ENSMUST00000151057, XM_006537063 (1778 bp), XM_006538525 (1778 bp), XM_006538526 (1884 bp), XM_006538527 (1766 bp)
Official symbol Ankrd37 [Rat]
Official name ankyrin repeat domain 37
Species Rat (Rattus norvegicus)
Entrez Gene ID 361149
Transcript(s) for this gene NM_001108400 (793 bp), XM_001061163 (911 bp), XM_341434 (911 bp)
Official symbol ANKRD37 [Human]
Official name ankyrin repeat domain 37
Species Human (Homo sapiens)
Entrez Gene ID 353322
Transcript(s) for this gene NM_181726 (934 bp), ENST00000511393, XM_005262981 (1161 bp), ENST00000335174
Official symbol Ankrd37 [Mouse]
Official name ankyrin repeat domain 37
Species Mouse (Mus musculus)
Entrez Gene ID 654824
Transcript(s) for this gene NM_001039562 (921 bp), ENSMUST00000153674, XM_006509474 (1049 bp), XM_006509475 (1496 bp)
Official symbol Pfkfb4 [Rat]
Official name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Species Rat (Rattus norvegicus)
Entrez Gene ID 54283
Transcript(s) for this gene NM_019333 (1739 bp), XM_006243840 (3070 bp), XM_006243841 (3064 bp), XM_006243842 (3032 bp), XM_008766563 (4111 bp)
Official symbol Egr1 [Rat]
Official name early growth response 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24330
Transcript(s) for this gene NM_012551 (1527 bp)
Official symbol EGR1 [Human]
Official name early growth response 1
Species Human (Homo sapiens)
Entrez Gene ID 1958
Transcript(s) for this gene NM_001964 (3136 bp), ENST00000239938
Official symbol Egr1 [Mouse]
Official name early growth response 1
Species Mouse (Mus musculus)
Entrez Gene ID 13653
Transcript(s) for this gene NM_007913 (3072 bp)
Official symbol Hif3a [Rat]
Official name hypoxia inducible factor 3, alpha subunit
Species Rat (Rattus norvegicus)
Entrez Gene ID 64345
Transcript(s) for this gene NM_022528 (2076 bp)
Official symbol Nos3 [Rat]
Official name nitric oxide synthase 3, endothelial cell
Species Rat (Rattus norvegicus)
Entrez Gene ID 24600
Transcript(s) for this gene NM_021838 (3953 bp), XM_006235872 (4162 bp)
Official symbol Egln1 [Rat]
Official name egl-9 family hypoxia-inducible factor 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 308913
Transcript(s) for this gene NM_178334 (1607 bp), XM_002725436 (3101 bp), XM_002728611 (3596 bp), XM_008772679 (3968 bp)
Official symbol TFRC [Human]
Official name transferrin receptor
Species Human (Homo sapiens)
Entrez Gene ID 7037
Transcript(s) for this gene NM_001128148 (5100 bp), NM_003234 (5241 bp), ENST00000491658, ENST00000360110, ENST00000392396, ENST00000420415
Official symbol Tfrc [Mouse]
Official name transferrin receptor
Species Mouse (Mus musculus)
Entrez Gene ID 22042
Transcript(s) for this gene NM_011638 (4920 bp), ENSMUST00000155929, XM_006521999 (5033 bp)
Official symbol Tfrc [Rat]
Official name transferrin receptor
Species Rat (Rattus norvegicus)
Entrez Gene ID 64678
Transcript(s) for this gene NM_022712 (4805 bp), XM_001072774 (4789 bp), XM_340999 (4789 bp), XM_006248462 (4896 bp), XM_006248463 (4808 bp)
Official symbol SERPINE1 [Human]
Official name serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Species Human (Homo sapiens)
Entrez Gene ID 5054
Transcript(s) for this gene NM_000602 (3207 bp), NM_001165413 (3153 bp), ENST00000223095
Official symbol Serpine1 [Mouse]
Official name serine (or cysteine) peptidase inhibitor, clade E, member 1
Species Mouse (Mus musculus)
Entrez Gene ID 18787
Transcript(s) for this gene NM_008871 (3024 bp)
Official symbol Serpine1 [Rat]
Official name serpin family E member 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24617
Transcript(s) for this gene NM_012620 (3053 bp)
Official symbol PFKFB4 [Human]
Official name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Species Human (Homo sapiens)
Entrez Gene ID 5210
Transcript(s) for this gene NM_004567 (3503 bp), ENST00000496767, ENST00000467176, XM_005265230 (3426 bp), XM_005265231 (3655 bp), ENST00000232375, ENST00000383734, ENST00000416568
Official symbol Pfkfb4 [Mouse]
Official name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Species Mouse (Mus musculus)
Entrez Gene ID 270198
Transcript(s) for this gene NM_001039215 (1841 bp), NM_001039216 (1712 bp), NM_001039217 (1751 bp), NM_173019 (3377 bp), ENSMUST00000154190, ENSMUST00000152220, XM_006512133 (3426 bp), XM_006512134 (3234 bp), XM_006512135 (3228 bp), XM_006512136 (3610 bp), XM_006512137 (3385 bp), XM_006512138 (3269 bp), XM_006512139 (2309 bp), XM_011242973 (3118 bp)
Official symbol EGLN1 [Human]
Official name egl-9 family hypoxia inducible factor 1
Species Human (Homo sapiens)
Entrez Gene ID 54583
Transcript(s) for this gene NM_022051 (7102 bp), ENST00000476717, XM_005273166 (4301 bp), XM_005273167 (4232 bp), XM_006711782 (2701 bp), ENST00000366641
Official symbol Egln1 [Mouse]
Official name egl-9 family hypoxia-inducible factor 1
Species Mouse (Mus musculus)
Entrez Gene ID 112405
Transcript(s) for this gene NM_053207 (3524 bp), XM_006530578 (3453 bp)
Official symbol ODC1 [Human]
Official name ornithine decarboxylase 1
Species Human (Homo sapiens)
Entrez Gene ID 4953
Transcript(s) for this gene NM_002539 (2307 bp), ENST00000446285, NM_001287188 (2207 bp), NM_001287189 (2199 bp), NM_001287190 (2045 bp), ENST00000234111, ENST00000405333
Official symbol PIM1 [Human]
Official name Pim-1 proto-oncogene, serine/threonine kinase
Species Human (Homo sapiens)
Entrez Gene ID 5292
Transcript(s) for this gene NM_001243186 (2751 bp), NM_002648 (2751 bp), ENST00000479509, ENST00000373509
Official symbol Pim1 [Mouse]
Official name proviral integration site 1
Species Mouse (Mus musculus)
Entrez Gene ID 18712
Transcript(s) for this gene NM_008842 (1769 bp), XM_991765 (2260 bp)
Official symbol Pim1 [Rat]
Official name Pim-1 proto-oncogene, serine/threonine kinase
Species Rat (Rattus norvegicus)
Entrez Gene ID 24649
Transcript(s) for this gene NM_017034 (1302 bp)
Official symbol ALDOA [Human]
Official name aldolase A, fructose-bisphosphate
Species Human (Homo sapiens)
Entrez Gene ID 226
Transcript(s) for this gene NM_000034 (2408 bp), NM_001127617 (1630 bp), NM_001243177 (1751 bp), NM_184041 (1597 bp), NM_184043 (1569 bp), ENST00000575627, XM_006721109 (743 bp), ENST00000338110, ENST00000395240, ENST00000395248, ENST00000412304, ENST00000563060, ENST00000564546, ENST00000564595, ENST00000566897, ENST00000569545, ENST00000569798, ENST00000627059
Official symbol Aldoa [Mouse]
Official name aldolase A, fructose-bisphosphate
Species Mouse (Mus musculus)
Entrez Gene ID 11674
Transcript(s) for this gene NM_001177307 (1597 bp), NM_001177308 (1470 bp), NM_007438 (1520 bp), ENSMUST00000147748, ENSMUST00000143509, XM_006507209 (1484 bp), XM_006507210 (1405 bp), XM_006507211 (1614 bp)
Official symbol Aldoa [Rat]
Official name aldolase, fructose-bisphosphate A
Species Rat (Rattus norvegicus)
Entrez Gene ID 24189
Transcript(s) for this gene NM_001177305 (1363 bp), NM_012495 (1465 bp), NM_001271536 (1449 bp), XM_006230209 (1688 bp), XM_006230210 (1598 bp), XM_006230211 (1453 bp)
Official symbol Adora2b [Mouse]
Official name adenosine A2b receptor
Species Mouse (Mus musculus)
Entrez Gene ID 11541
Transcript(s) for this gene NM_007413 (1844 bp), XM_974238 (1567 bp)
Official symbol ADORA2B [Human]
Official name adenosine A2b receptor
Species Human (Homo sapiens)
Entrez Gene ID 136
Transcript(s) for this gene NM_000676 (1885 bp), ENST00000582124, ENST00000304222
Official symbol Adora2b [Rat]
Official name adenosine A2B receptor
Species Rat (Rattus norvegicus)
Entrez Gene ID 29316
Transcript(s) for this gene NM_017161 (1859 bp)
Official symbol NCOA1 [Human]
Official name nuclear receptor coactivator 1
Species Human (Homo sapiens)
Entrez Gene ID 8648
Transcript(s) for this gene NM_003743 (6895 bp), NM_147223 (6952 bp), NM_147233 (6892 bp), ENST00000496333, XM_005264625 (7060 bp), XM_005264626 (6811 bp), XM_005264627 (6871 bp), XM_005264628 (6868 bp), XM_006712126 (6673 bp), ENST00000288599, ENST00000348332, ENST00000395856, ENST00000405141, ENST00000406961, ENST00000407230
Official symbol Ncoa1 [Rat]
Official name nuclear receptor coactivator 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 313929
Transcript(s) for this gene NM_001108012 (5290 bp), XM_001070473 (6911 bp), XM_233944 (6911 bp), XM_006239842 (7886 bp), XM_006239843 (7118 bp), XM_006239844 (7883 bp), XM_006239845 (7941 bp), XM_006239846 (7938 bp)
Official symbol Hif1an [Mouse]
Official name hypoxia-inducible factor 1, alpha subunit inhibitor
Species Mouse (Mus musculus)
Entrez Gene ID 319594
Transcript(s) for this gene NM_176958 (6190 bp), ENSMUST00000131032
Official symbol HIF1AN [Human]
Official name hypoxia inducible factor 1, alpha subunit inhibitor
Species Human (Homo sapiens)
Entrez Gene ID 55662
Transcript(s) for this gene NM_017902 (6928 bp), ENST00000528044, ENST00000299163
Official symbol Hif1an [Rat]
Official name hypoxia-inducible factor 1, alpha subunit inhibitor
Species Rat (Rattus norvegicus)
Entrez Gene ID 309434
Transcript(s) for this gene NM_001113749 (1363 bp), XM_001062399 (1634 bp), XM_219961 (1634 bp), XM_347187 (1050 bp)
Official symbol Dnajc5 [Mouse]
Official name DnaJ heat shock protein family (Hsp40) member C5
Species Mouse (Mus musculus)
Entrez Gene ID 13002
Transcript(s) for this gene NM_016775 (4325 bp), XM_990872 (1126 bp), NM_001271584 (4378 bp), NM_001271585 (4405 bp), XM_011239923 (4313 bp), XM_011239924 (4142 bp)
Official symbol DNAJC5 [Human]
Official name DnaJ (Hsp40) homolog, subfamily C, member 5
Species Human (Homo sapiens)
Entrez Gene ID 80331
Transcript(s) for this gene NM_025219 (5307 bp), ENST00000360864
Official symbol Dnajc5 [Rat]
Official name DnaJ (Hsp40) homolog, subfamily C, member 5
Species Rat (Rattus norvegicus)
Entrez Gene ID 79130
Transcript(s) for this gene NM_024161 (937 bp), XM_008762544 (4241 bp), XM_008762545 (4282 bp)
Official symbol Anxa2 [Mouse]
Official name annexin A2
Species Mouse (Mus musculus)
Entrez Gene ID 12306
Transcript(s) for this gene NM_007585 (1374 bp), XM_622573 (948 bp), ENSMUST00000154591, XM_006510796 (1739 bp)
Official symbol ANXA2 [Human]
Official name annexin A2
Species Human (Homo sapiens)
Entrez Gene ID 302
Transcript(s) for this gene NM_001002857 (1644 bp), NM_001002858 (1632 bp), NM_001136015 (1665 bp), NM_004039 (1563 bp), ENST00000561445, ENST00000332680, ENST00000396024, ENST00000421017, ENST00000451270, XM_011521475 (2237 bp), XM_011521476 (1834 bp), XM_011521477 (1336 bp)
Official symbol Anxa2 [Rat]
Official name annexin A2
Species Rat (Rattus norvegicus)
Entrez Gene ID 56611
Transcript(s) for this gene NM_019905 (1395 bp)
Official symbol Rbpj [Mouse]
Official name recombination signal binding protein for immunoglobulin kappa J region
Species Mouse (Mus musculus)
Entrez Gene ID 19664
Transcript(s) for this gene NM_001080927 (5508 bp), NM_001080928 (5394 bp), NM_009035 (5410 bp), NM_001277116 (5590 bp), XM_006503795 (6391 bp), XM_006503796 (5830 bp), XM_006503797 (5297 bp), XM_006503798 (5189 bp), XM_006503799 (6205 bp)
Official symbol RBPJ [Human]
Official name recombination signal binding protein for immunoglobulin kappa J region
Species Human (Homo sapiens)
Entrez Gene ID 3516
Transcript(s) for this gene NM_005349 (5878 bp), NM_015874 (5825 bp), NM_203283 (5762 bp), NM_203284 (6008 bp), ENST00000515023, XM_005248161 (5664 bp), XM_006713962 (5565 bp), XM_006713963 (5843 bp), XM_006713964 (5385 bp), ENST00000342295, ENST00000342320, ENST00000345843, ENST00000348160, ENST00000355476, ENST00000361572, ENST00000504907, ENST00000507561, XM_011513840 (6026 bp), XM_011513841 (5607 bp)
Official symbol Atr [Mouse]
Official name ataxia telangiectasia and Rad3 related
Species Mouse (Mus musculus)
Entrez Gene ID 245000
Transcript(s) for this gene NM_019864 (8074 bp), XM_147046 (7805 bp), XM_006511184 (9172 bp), XM_006511185 (7778 bp), XM_006511186 (6434 bp), XM_006511187 (6028 bp), XM_006511188 (5314 bp), XM_011242749 (4625 bp)
Official symbol ATR [Human]
Official name ATR serine/threonine kinase
Species Human (Homo sapiens)
Entrez Gene ID 545
Transcript(s) for this gene NM_001184 (8258 bp), XM_001131387 (8006 bp), ENST00000515863, XR_241498 (10880 bp), ENST00000350721
Official symbol Nampt [Mouse]
Official name nicotinamide phosphoribosyltransferase
Species Mouse (Mus musculus)
Entrez Gene ID 59027
Transcript(s) for this gene NM_021524 (4547 bp)
Official symbol NAMPT [Human]
Official name nicotinamide phosphoribosyltransferase
Species Human (Homo sapiens)
Entrez Gene ID 10135
Transcript(s) for this gene NM_005746 (4593 bp), NM_182790 (1240 bp), ENST00000491027, XM_005250100 (4541 bp), ENST00000222553, ENST00000354289, XM_011515707 (2489 bp)
Official symbol Ero1l [Mouse]
Official name ERO1-like (S. cerevisiae)
Species Mouse (Mus musculus)
Entrez Gene ID 50527
Transcript(s) for this gene NM_015774 (4435 bp), XM_990342 (2430 bp)
Official symbol ERO1L [Human]
Official name ERO1-like (S. cerevisiae)
Species Human (Homo sapiens)
Entrez Gene ID 30001
Transcript(s) for this gene NM_014584 (3334 bp), ENST00000557178, ENST00000395686, ENST00000629528
Official symbol Ero1a [Rat]
Official name endoplasmic reticulum oxidoreductase 1 alpha
Species Rat (Rattus norvegicus)
Entrez Gene ID 171562
Transcript(s) for this gene NM_138528 (2361 bp)
Official symbol Nos3 [Mouse]
Official name nitric oxide synthase 3, endothelial cell
Species Mouse (Mus musculus)
Entrez Gene ID 18127
Transcript(s) for this gene NM_008713 (4140 bp), XM_006535639 (3925 bp)
Official symbol NOS3 [Human]
Official name nitric oxide synthase 3 (endothelial cell)
Species Human (Homo sapiens)
Entrez Gene ID 4846
Transcript(s) for this gene NM_000603 (4345 bp), NM_001160109 (2040 bp), NM_001160110 (2386 bp), NM_001160111 (2546 bp), ENST00000477227, ENST00000468293, XM_006716000 (4440 bp), XM_006716001 (3835 bp), XM_006716002 (2458 bp), ENST00000297494, ENST00000461406, ENST00000467517, ENST00000484524
Official symbol Hk2 [Mouse]
Official name hexokinase 2
Species Mouse (Mus musculus)
Entrez Gene ID 15277
Transcript(s) for this gene NM_013820 (5524 bp), XM_989633 (2366 bp), ENSMUST00000168725, XM_006505606 (4985 bp)
Official symbol HK2 [Human]
Official name hexokinase 2
Species Human (Homo sapiens)
Entrez Gene ID 3099
Transcript(s) for this gene NM_000189 (7109 bp), ENST00000472302, XM_005264280 (5636 bp), ENST00000290573, ENST00000409174
Official symbol Hk2 [Rat]
Official name hexokinase 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 25059
Transcript(s) for this gene NM_012735 (3633 bp), XM_006236711 (6186 bp)
Official symbol GYS1 [Human]
Official name glycogen synthase 1 (muscle)
Species Human (Homo sapiens)
Entrez Gene ID 2997
Transcript(s) for this gene NM_001161587 (3443 bp), NM_002103 (3635 bp), NR_027763 (3453 bp), ENST00000263276, ENST00000323798
Official symbol Gys1 [Rat]
Official name glycogen synthase 1, muscle
Species Rat (Rattus norvegicus)
Entrez Gene ID 690987
Transcript(s) for this gene NM_001109615 (3691 bp), XM_001076910 (3744 bp), XM_001076928 (3729 bp), XM_001076950 (3729 bp), XM_001076978 (3717 bp), XM_001077000 (3717 bp), XM_001079274 (3744 bp), XM_001079287 (3729 bp), XM_001079300 (3717 bp), XM_001079314 (3717 bp)
Official symbol Slc2a3 [Mouse]
Official name solute carrier family 2 (facilitated glucose transporter), member 3
Species Mouse (Mus musculus)
Entrez Gene ID 20527
Transcript(s) for this gene NM_011401 (3973 bp), ENSMUST00000169979, XM_006505822 (4337 bp), XM_006505823 (4055 bp), XM_011241268 (4110 bp)
Official symbol SLC2A3 [Human]
Official name solute carrier family 2 (facilitated glucose transporter), member 3
Species Human (Homo sapiens)
Entrez Gene ID 6515
Transcript(s) for this gene NM_006931 (3938 bp), ENST00000543435, ENST00000075120
Official symbol Slc2a3 [Rat]
Official name solute carrier family 2 (facilitated glucose transporter), member 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 25551
Transcript(s) for this gene NM_017102 (1482 bp), XM_006237295 (3839 bp), XM_006237296 (4158 bp), XM_006237297 (3843 bp), XM_006237298 (4121 bp)
Official symbol F10 [Mouse]
Official name coagulation factor X
Species Mouse (Mus musculus)
Entrez Gene ID 14058
Transcript(s) for this gene NM_001242368 (2693 bp), NM_007972 (2503 bp)
Official symbol F10 [Human]
Official name coagulation factor X
Species Human (Homo sapiens)
Entrez Gene ID 2159
Transcript(s) for this gene NM_000504 (1560 bp), ENST00000498455, XM_005268298 (1515 bp), XM_006719964 (1367 bp), ENST00000375551, ENST00000375559, ENST00000409306
Official symbol F10 [Rat]
Official name coagulation factor X
Species Rat (Rattus norvegicus)
Entrez Gene ID 29243
Transcript(s) for this gene NM_017143 (1618 bp)
Official symbol Gys1 [Mouse]
Official name glycogen synthase 1, muscle
Species Mouse (Mus musculus)
Entrez Gene ID 14936
Transcript(s) for this gene NM_030678 (3681 bp), ENSMUST00000150689
Official symbol Ncoa1 [Mouse]
Official name nuclear receptor coactivator 1
Species Mouse (Mus musculus)
Entrez Gene ID 17977
Transcript(s) for this gene NM_010881 (7346 bp), XM_001000135 (6581 bp), XM_976948 (6581 bp), XM_006515005 (7302 bp), XM_006515006 (6957 bp), XM_006515007 (7435 bp), XM_006515008 (7298 bp), XM_006515009 (5274 bp), XM_006515010 (5703 bp), XM_011243839 (6749 bp), XM_011243840 (6954 bp), XM_011243841 (4930 bp)
Official symbol Usf2 [Mouse]
Official name upstream transcription factor 2
Species Mouse (Mus musculus)
Entrez Gene ID 22282
Transcript(s) for this gene NM_011680 (2419 bp), XM_001001413 (2454 bp), ENSMUST00000171338, XM_006539733 (1917 bp), XM_006539734 (1372 bp), XM_006539735 (1600 bp)
Official symbol USF2 [Human]
Official name upstream transcription factor 2, c-fos interacting
Species Human (Homo sapiens)
Entrez Gene ID 7392
Transcript(s) for this gene NM_003367 (1732 bp), NM_207291 (1531 bp), ENST00000607959, XM_005259197 (1161 bp), ENST00000222305, ENST00000343550, ENST00000379134, ENST00000594064, ENST00000595068
Official symbol Usf2 [Rat]
Official name upstream transcription factor 2, c-fos interacting
Species Rat (Rattus norvegicus)
Entrez Gene ID 81817
Transcript(s) for this gene NM_031139 (2171 bp), XM_001079341 (1738 bp)
Official symbol Pgam1 [Mouse]
Official name phosphoglycerate mutase 1
Species Mouse (Mus musculus)
Entrez Gene ID 18648
Transcript(s) for this gene NM_023418 (1855 bp)
Official symbol PGAM1 [Human]
Official name phosphoglycerate mutase 1 (brain)
Species Human (Homo sapiens)
Entrez Gene ID 5223
Transcript(s) for this gene NM_002629 (1762 bp), ENST00000473929, ENST00000334828
Official symbol Hif3a [Mouse]
Official name hypoxia inducible factor 3, alpha subunit
Species Mouse (Mus musculus)
Entrez Gene ID 53417
Transcript(s) for this gene NM_001162950 (6916 bp), NM_016868 (6947 bp), XM_989804 (2436 bp), ENSMUST00000139224, XM_011250628 (7622 bp)
Official symbol HIF3A [Human]
Official name hypoxia inducible factor 3, alpha subunit
Species Human (Homo sapiens)
Entrez Gene ID 64344
Transcript(s) for this gene NM_022462 (5803 bp), NM_152794 (5899 bp), NM_152795 (5867 bp), NM_152796 (1777 bp), ENST00000600236, XM_005259152 (5968 bp), XM_005259153 (2073 bp), XM_005259154 (5690 bp), XM_005259155 (5699 bp), XM_005259156 (1823 bp), XM_006723324 (5815 bp), XM_006723325 (5704 bp), ENST00000244303, ENST00000300862, ENST00000377670, ENST00000472815, ENST00000600383
Official symbol Pkm [Mouse]
Official name pyruvate kinase, muscle
Species Mouse (Mus musculus)
Entrez Gene ID 18746
Transcript(s) for this gene NM_001253883 (2432 bp), NM_011099 (2432 bp), XM_979537 (3585 bp), XM_979576 (2338 bp), XM_979609 (5769 bp), XM_979652 (2319 bp), XM_979685 (2208 bp), XM_979725 (2402 bp), XM_979753 (2548 bp), XM_979779 (2457 bp), XM_979805 (2251 bp), XM_979833 (2211 bp), XM_979863 (2395 bp), XM_979890 (6941 bp), XM_979922 (7046 bp), XM_979949 (7046 bp), XM_006510848 (2380 bp), XM_006510849 (2380 bp), XM_006510850 (2368 bp), XM_006510851 (2353 bp), XM_006510852 (2344 bp), XM_006510853 (2341 bp), XM_006510854 (2314 bp), XM_006510855 (2375 bp), XM_006510856 (2104 bp), XM_011242673 (2259 bp), XM_011242674 (2370 bp)
Official symbol Gbe1 [Rat]
Official name glucan (1,4-alpha-), branching enzyme 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 288333
Transcript(s) for this gene NM_001100502 (2937 bp), XM_001064453 (2991 bp), XM_221747 (3033 bp)
Official symbol Jmjd6 [Rat]
Official name jumonji domain containing 6
Species Rat (Rattus norvegicus)
Entrez Gene ID 360665
Transcript(s) for this gene NM_001012143 (1730 bp), XM_340941 (1358 bp), XM_006247806 (1584 bp), XR_358006 (0 bp)

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