Female sientist holding a tube

Bulk Oligos

At OEM by QIAGEN, we know that high-quality, pure oligonucleotides can make a difference. We manufacture premium quality custom oligos in big batches for molecular and in-vitro diagnostic applications, using AIE-HPLC and RP-HPLC methods, resulting in a very high purity level. Critical raw materials are tested and approved before use in bulk production for lot-to-lot reproducibility. Synthesis processes are optimized and automated to meet stringent requirements, including a no-contamination guarantee for IVD-grade. Moreover, we work according to cGMP/QSR guidelines in ISO-certified facilities, providing full traceability with extensive Production Batch Records.

To learn more, check out the interactive brochure.

  Fast track Development-LC Development-HPLC IVD
Traceability None Partial
Purification LC/HPLC LC HPLC
HPLC column Non dedicated N/A Non dedicated


Clean room None Optional Optional
Quality systems ISO 9001 ISO 9001
ISO 13485
ISO 9001
ISO 13485

ISO 9001
ISO 13485
21 CFR Part 820

QC control Optional QC Optional QC Customized QC
In process/ Final
Product release Final QC Technical release Technical release
QA release
Documents provided Compilation of results Simplified CoA
Simplified CoA
Full CoA
Critical raw material control Partial Partial
Environmental control Yes  Yes 
Manufacturing documents None Simplified production
batch record
Simplified production
batch record
batch record
Synthesis scale 0.04–0.1 μmol 0.15–60 μmol
1–60 μmol
1–60 μmol
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* Analytical methods for troubleshooting or evaluation of third-party products.

Compliant, certified facilities

ISO and GMP certified manufacturing facilities in multiple sites worldwide provide you with access to our broad range of custom oligos and other OEM products. At OEM by QIAGEN, we pride ourselves on excellent quality control processes, global reach and long-term customer support. We help assay developers consolidate the supply chain to get bulk components exactly where and when needed.

Compliant, certified facilities
Custom LNA oligos

Custom LNA oligos

Designing Locked Nucleic Acid (LNA) oligonucleotides is complex and requires expertise. We can support you with off-the-shelf or custom LNA oligos manufactured in big batches.

Oligonucleotide categories
Unmodified oligonucleotides
Modified oligonucleotides

• Primers
• Probes
• Locked Nucleic Acid (LNA)
• NGS Adapters
• Molecular Beacons

• Unmodified oligonucleotides up to 170 bases
• Homopolymers such as polyA and polyT
• Fluorescent groups
• Fluorescent groups combined with Quenchers
• LNA® containing oligonucleotides
• MGB-Eclipse® Dark Quencher
• Superbases
• SuperA®, SuperG® and SuperT®
• Biotin
• Phosphate
• Spacers
• Amino
… and more
Oligo modifications
Take a look at further modification capabilities of OEM oligonucleotides in bulk.