High-resolution melting (HRM) is a novel technology for fast and accurate genetic analysis. HRM is a powerful and cost-effective solution for analyzing previously unknown and even complex sequence variations in a multitude of applications.
HRM technology characterizes double-stranded PCR products based on their melting behavior, as they transition from double-stranded DNA to single-stranded DNA with increasing temperature. HRM offers unique advantages over other technologies that make it a definitive analysis and detection technology for various applications.
QIAGEN offers a complete solution for HRM-based genetic analysis. From dedicated HRM PCR kits to a real-time instrument with HRM capabilities and a powerful software package for data analysis — optimized solutions for HRM analysis are simply a click away!
Choose the right product for your needs with our helpful selection guide.
| SNP and mutation genotyping |
Type-it HRM PCR Kit |
- Rotor-Gene Q and Rotor-Gene ScreenClust HRM Software
- LightCycler 480
- ABI 7500
- Other cyclers with HRM capability
|
| Mutation screening |
Type-it HRM PCR Kit |
- Rotor-Gene Q & Rotor-Gene ScreenClust HRM Software
- LightCycler 480
- ABI 7500
- Other cyclers with HRM capability
|
| Pathogen detection |
Type-it HRM PCR Kit |
- Rotor-Gene Q & Rotor-Gene ScreenClust HRM Software
- LightCycler 480
- ABI 7500
- Other cyclers with HRM capability
|
| CpG analysis (with quantification of methylation status) or screening for changes in methylation status |
EpiTect HRM PCR Kit |
- Rotor-Gene Q
- LightCycler 480
- ABI 7500
- Other cyclers with HRM capability
|
| CpG analysis (without quantification of methylation status) |
EpiTect HRM PCR Kit |
- Rotor-Gene Q & Rotor-Gene ScreenClust HRM Software
- LightCycler 480
- ABI 7500
- Other cyclers with HRM capability
|