PRKCD
Full Name: protein kinase C, delta
Synonyms: MAY1, OTTHUMP00000165025...
SpeciesHuman
Gene ID5580
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Product(s)
Summary
Interaction Network
Pathways
 
 
Available Products
1
Product Product no. Cat. no. List price:
(ENSG00000163932). PCR and sequencing primers for Pyrosequencing analysis of gene-specific CpG methylation after DNA bisulfite conversion (200 reactions; tube format)
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978746 PM00015946 $88.30
Laboratory-verified forward and reverse primers for 200 reactions
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335002 EPHS110330
-1A
$236.00
Laboratory-verified forward and reverse primers for 200 reactions
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335002 EPHS110331
-1A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)01A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)02A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)03A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)04A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)05A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)06A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)07A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)08A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)09A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)10A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)11A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)12A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)13A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)20A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)19A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)18A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)17A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)16A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)15A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(-)14A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(+)01A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(+)02A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(+)03A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(+)04A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1009351
(+)05A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1009351
(+)06A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1009351
(+)07A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1009351
(+)08A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(+)09A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1009351
(+)10A
$236.00
EpiTect ChIP qPCR Array - Pathway
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334211 GH-507A varies
Configure
Product Product no. Cat. no. List price:
 
 
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Pathways containing this gene
87
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The 14-3-3 proteins are a family of conserved adaptor and scaffolding proteins expressed in all eukaryotic cells. It has evolved from a brain-specific protein to a family of ubiquitously expressed... Show details
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cAMP (Cyclic 3, 5-Adenosine Monophosphate)-dependent Protein Kinase, commonly known as PKA (Protein Kinase-A), is a second messenger-dependent enzyme that has been implicated in a wide range of... Show details
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PKA (Protein Kinase-A) is a second messenger-dependent enzyme that has been implicated in a wide range of cellular processes, including transcription, metabolism, cell cycle progression and... Show details
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PKC (Protein Kinase-C) is a cyclic nucleotide-independent enzyme that phosphorylates serine and threonine residues in many target proteins. PKC plays a pivotal role in mediating cellular responses... Show details
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Sodium transport across the tight epithelia of Na+ reabsorbing tissues such as the distal nephron and colon is the major factor determining total body Na+ levels, and thus, long term blood... Show details
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ADRs (Adrenergic Receptors) are expressed on virtually every cell type in the body and are the receptors for Adrenaline, Epinephrine and Norepinephrine within the Sympathetic Nervous System. They... Show details
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Alzheimer disease (AD) is a progressive neurodegenerative disorder caused by an increase in amyloid metabolism. Mutations in some of the components of the amyloid pathway, such as the amyloid... Show details
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Androgens mediate a wide range of developmental and physiological responses and are especially important in male sexual differentiation and pubertal sexual maturation, the maintenance of... Show details
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Oxidative stress/Hypoxia is induced by a wide range of environmental factors including UV stress, pathogen invasion (hypersensitive reaction), oxygen shortage, etc. Generation of ROS (Reactive... Show details
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The BCR (B-Cell antigen Receptor) plays a critical role in development, survival, and activation of B cells. The BCR is composed of mIg molecules (Membrane Immunoglobulin) and associated... Show details
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The sense of taste plays a critical role in the life and nutritional status of humans and other organisms. Human taste perception may be categorized according to four well known and widely... Show details
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Stmn1 (Stathmin-1) also referred to as Op18 (Oncoprotein-18) is a major regulator of microtubule dynamics. It is an evolutionarily well conserved 17 kDa cytoplasmic phosphoprotein that is highly... Show details
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Ca2+ (Calcium) plays a major role in life and death within T-Cells. Elevation of intracellular free Ca2+ is one of the key triggering signals for T-Cell activation by antigen. The binding of... Show details
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cAMP (Cyclic Adenosine 3,5-monophosphate) is the first identified second messenger, which has a fundamental role in the cellular response to many extracellular stimuli. The cAMP signaling pathway... Show details
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Multicellular organisms have developed highly efficient mechanisms of cell communication to integrate and coordinate the function and proliferation of individual cell types. Gastrointestinal... Show details
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Human eosinophils are crucial effector cells implicated in a number of chronic inflammatory reactions, associated with bronchial asthma, allergic-inflammatory diseases, and parasitic infections... Show details
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CCR5 (Chemokine-CC Motif-Receptor-5) is a member of the chemokine receptor subclass of the GPCR (G-Protein-Coupled Receptor) superfamily (Ref.1). It regulates leukocyte chemotaxis in inflammation... Show details
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Apoptosis is a naturally occurring process by which a cell is directed to Programmed Cell Death. Apoptosis is based on a genetic program that is an indispensable part of the development and... Show details
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The SM (Sphingomyelin) pathway is an evolutionarily conserved stress response system linking diverse environmental stresses (Ultraviolet, Heat Shock, Oxidative Stress, and Ionizing Radiation) to... Show details
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Chemokines, or chemotactic cytokines, are a large family of small (6-14 kDa), structurally related proteins that mediate a wide range of biological activities. As a part of normal immune system... Show details
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Cholera is one of the most severe diarrheal diseases that affect humans and is responsible for significant morbidity and mortality especially among children in developing countries. It is... Show details
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The process of consolidating a new memory and the dynamic complexity of information processing within neuronal networks is greatly increased by activity-dependent changes in gene expression... Show details
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CRH (Corticotropin-Releasing Hormone) and related peptides play a major role in coordinating the behavioral, endocrine, cardiovascular, autonomic and immune mechanisms that allow mammals to adapt... Show details
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The Chemokine receptor CXCR4 is a 352 amino acid rhodopsin-like GPCR and selectively binds the CXC chemokine Stromal Cell-Derived Factor 1 (SDF-1) also known as CXCL12. This receptor has been... Show details
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One of the ultimate frontiers for mankind is the elucidation of the function of the mind. Dopaminergic and Glutamergic are two primary neurotransmitter systems in the brain, which are crucially... Show details
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EGF (Epidermal Growth Factor) is a small 53 amino acid residue protein that is involved in normal cell growth, oncogenesis, and wound healing. This protein shows both strong sequential and... Show details
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Cardiac hypertrophy describes an abnormal condition where the heart becomes enlarged. Several factors, such as increased mechanical loading and neuro-hormonal chemicals can induce hypertrophy. ET1... Show details
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Pathogenic microbes subvert normal host-cell processes to create a specialized niche, which enhances their survival. A common and recurring target of pathogens is the host cells cytoskeleton,... Show details
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The ErbB (Erythroblastic Leukemia Viral Oncogene Homolog) or EGF (Epidermal Growth Factor) family of transmembrane PTKs (Receptor Tyrosine Kinases) plays an important role during the growth and... Show details
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The ErbB tyrosine kinases (epidermal growth factor receptor (EGFR), ErbB2/HER2, ErbB3, and ErbB4) are cell surface growth factor receptors widely expressed in many developing mammalian tissues,... Show details
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The ErbB receptor tyrosine kinases comprise the four members, epidermal growth factor receptor (EGFR)/ErbB1, Her2/ErbB2, ErbB3 and ErbB4. ErbB-family members are known to play critical roles in... Show details
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The MAPK (Mitogen-Activated Protein Kinase) pathway is one of the primordial signaling systems that nature has used in several permutations to accomplish an amazing variety of tasks. It exists in... Show details
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Heart is the first organ to form and function in the Embryo, and all subsequent events in the life of the organism depend on the Hearts ability to match its output with... Show details
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Angiogenesis, the growth of new blood vessels, plays a key role in many physiological and pathological processes, such as ovulation, embryogenesis, wound repair, inflammation, malignant tumor... Show details
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Neutrophils play an important role in the host defense by invading microbial pathogens. Upon infection neutrophils become activated through interaction with chemo attractants and cytokines. These... Show details
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GPCR (G-Protein-Coupled Receptors) constitute a large and diverse family of proteins whose primary function is to transduce extracellular stimuli into intracellular signals. They are among the... Show details
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G-proteins (Guanine Nucleotide-Binding Proteins) are heterotrimeric proteins that mediate signal transduction between many membrane-bound receptors and intracellular effectors. Traditionally,... Show details
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Glioblastoma Multiforme (GBM) is biologically aggressive neoplasms which have an elevated, often aberrant, prolifetraive capacity with a diffuse pattern of brain invasion. It is the most malignant... Show details
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Normal mammalian sexual maturation and reproductive functions require the integration and precise coordination of hormones at the hypothalamic, pituitary, and gonadal levels. The hypothalamic GnRH... Show details
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GPCRs (Guanine Nucleotide Binding-Protein Coupled Receptors) comprise large and diverse gene families in fungi, plants, and the animal kingdom. Also termed serpentine receptors, GPCRs are... Show details
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Most aging individuals die from atherosclerosis, cancer, or dementia; but in the oldest old, loss of muscle strength resulting in frailty is the limiting factor for an individuals chances of... Show details
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Huntingtons disease, also known as Huntington Chorea, is a dominantly inherited Neurodegenerative disorder featuring progressively worsening Chorea, Psychiatric disturbances and Cognitive... Show details
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IL-2 (Interleukin-2) is a T-Cell-derived cytokine important in the regulation of growth and differentiation of T-Cells, B-Cells, natural killer cells, glioma cells, and cells of the monocyte... Show details
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IL-3 (Interleukin-3) is a cytokine that regulates haemopoiesis, the formation of blood cells in the body. IL-3, also called multi-CSF (multi-lineage colony stimulating factor), is produced by T... Show details
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Insulin is the major hormone controlling critical energy functions such as glucose and lipid metabolism. Insulin elicits a diverse array of biological responses by binding to its specific receptor... Show details
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To thwart viral infection, our cells have developed a formidable and integrated defense network that comprise of innate and adaptive immune responses. In an attempt to prevent viral replication,... Show details
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Despite tremendous diversities in their expression, cellular activities in virtually all cell types are regulated by common intracellular signaling systems, and calcium is one important ubiquitous... Show details
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Development of a proper immune system requires the selection of lymphocytes expressing a useful repertoire of antigen receptors that can respond to foreign or dangerous antigens but not to self.... Show details
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Endotoxin LPS (Lipopolysaccharide) is a component of the outer membrane of Gram-negative bacteria that potently promotes the activation of macrophages and microglia cells, which are important... Show details
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Mitogen-activated protein kinase pathways are evolutionarily conserved kinase modules that link extracellular signals to the machinery that controls fundamental cellular processes such as growth,... Show details
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In mammals, the circadian system is comprised of three major components: the lateral eyes, the hypothalamic SCN (Suprachiasmatic Nucleus) and the pineal gland. The SCN harbours the endogenous... Show details
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Apoptosis is a naturally occurring process by which a cell is directed to Programmed Cell Death. Apoptosis is based on a genetic program that is an indispensable part of the development and... Show details
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Cancer cell genotypes are a manifestation of six essential alterations in cell physiology that collectively dictate malignant growth; self-sufficiency in growth signals, insensitivity to... Show details
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Most organisms have evolved mechanisms for efficiently transitioning between anabolic and catabolic states, allowing them to survive and grow in environments in which nutrient availability is... Show details
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Living organisms need to sense noxious stimuli in their immediate environment to avoid potentially hazardous situations and thus survive. To this end, multicellular creatures have evolved a... Show details
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Cardiac failure, one of the largest health care burdens in the United States and other developed countries is often associated with prolonged and maladaptive cardiac hypertrophy, defined as a... Show details
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The EBV (Epstein-Barr Virus) is a member of the human herpes virus family, which infects greater than 90% of the world’s population. EBV is linked to the development of several malignancies,... Show details
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As viruses evolve under the highly selective pressures of the immune system, they acquire the capacity to target critical steps in the host cell life, hijacking vital cellular functions to promote... Show details
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NF-KappaB (Nuclear Factor-KappaB) is a heterodimeric protein composed of different combinations of members of the Rel family of transcription factors. The Rel/ NF-KappaB family of transcription... Show details
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One of the most fundamental issues in current biology is how to maintain the critical balance between cell survival and death, both during development and in adulthood. Unrestrained cell division... Show details
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NO (Nitric Oxide) is formed endogenously by a family of enzymes known as NOS (NO Synthases). The distribution of different isoforms of NOS is largely related to their respective functions. Three... Show details
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Cellular responses to many external stimuli involve the activation of several types of MAPK (Mitogen-Activated Protein Kinase) signaling pathways. MAPKs are a family of Serine/threonine kinases... Show details
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p70S6K is a protein Ser-Thr kinase that phosphorylates the ribosomal S6 subunit, a component of the 40S subunit of eukaryotic ribosomes. It plays a role in protein synthesis and in cell growth... Show details
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PACAP (Pituitary Adenylate Cyclase-Activating Polypeptide) is a member of the secretin glucagon-VIP (Vasoactive Intestinal Peptide) family of peptides and is widely distributed in the brain and... Show details
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Phagocytosis, a central component of the innate immune response, is the process whereby specialised cell types recognise and engulf foreign extracellular material. While lower organisms use... Show details
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Inositol lipid-specific PLC (Phospholipase-C) isozymes are key signaling proteins in the cellular action of many hormones, neurotransmitters, growth factors, and other extracellular stimuli. PLC... Show details
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The PI3K (Phosphatidylinositde-3-Kinase) family of enzymes regulate diverse biological functions in every cell type by generating lipid second messengers that ultimately results in the mediation... Show details
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PKA (Protein Kinase-A) is an enzyme that regulates processes as diverse as growth, development, memory, and metabolism. In its inactivated state, PKA exists as a tetrameric complex of two... Show details
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Prl (Prolactin), a multifunctional hormone secreted by the anterior pituitary gland and to a lesser extent by numerous extrapituitary tissues, affects more physiological processes than all other... Show details
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Tumorigenesis is the result of abnormal activation of growth programs in the cells. Most oncogene and tumor suppressor gene products are components of signal transduction pathways that control... Show details
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Proliferation and migration of VSMCs (Vascular Smooth Muscle Cells) in arteries plays an important role in the pathophysiology of atherosclerosis, hypertension, and restenosis after angioplasty. A... Show details
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Hypertrophic cardiomyopathy (HCM) is a monogenic cardiac disease with an autosomal dominant pattern of heritability and different penetrance, with a prevalence in the general population of... Show details
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Sperm cells are equipped with a limited repertoire of behaviors that exclusively subserve their purpose to fertilize eggs (mature ova). When produced in the testis, sperm are immotile; they... Show details
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The sense of taste plays a critical role in the life and nutritional status of humans and other organisms. Human taste perception may be categorized according to four well known and widely... Show details
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Nonreceptor PTKs (Protein Tyrosine Kinases) are essential for the development and activation of B-Cells and T-Cells (Ref.1). The Tec kinases represent the second largest family of mammalian... Show details
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The extended growth potential of cancer cells is critically dependent upon the maintenance of functional telomeres, which are specialized chromosomal DNA-protein structures in the terminal regions... Show details
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Thrombin is a multifunctional serine protease involved in a number of pathophysiological processes that include blood clotting, inflammation, repair processes and tumor metastasis. In brain,... Show details
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Throughout adult life, all blood cells are constantly regenerated from a small pool of hematopoietic stem cells. A single purified stem cell injected into a lethally irradiated host is sufficient... Show details
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The migratory properties of leukocytes or WBCs (White Blood Cells) are indispensable to drive immune responses throughout the body. Leukocytes fall under two categories according to their... Show details
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A recurring theme in neurobiology is the role of a set of molecules that support proliferation, differentiation and survival of neurons. These molecules, collectively referred to as neurotrophins,... Show details
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UV (Ultraviolet) radiation is a naturally occurring genotoxic agent and is the primary environmental carcinogen responsible for the development of most skin Cancers. The UV portion of solar... Show details
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UV (Ultraviolet) irradiation is a component of sunlight, which has higher energy than visible light. UV radiation (100 and 400 nm) is divided into at least three different categories based on... Show details
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Angiogenesis is important in embryonic development as well as in physiological events and dysregulated angiogenesis is involved in various pathological conditions, like solid tumor growth,... Show details
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VEGF (Vascular Endothelial Growth Factor) is a highly conserved genetic pathway that has evolved from simple to complex systems.The early evolutionary role of VEGF in simple invertebrate systems... Show details
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The formation of blood vessels occurs either by in situ differentiation of endothelial cell precursors (Angioblasts) and association of these cells to form primitive vessels, a process called... Show details
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Vitamin-A (all-trans-Retinol) is a vital and essential micronutrient in the human diet and is required for multiple physiological processes, ranging from vision to embryonic development.... Show details
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The development of tissues and organs in multicellular organisms is controlled by the interplay of several signaling pathways that cross talk to provide positional information and induce cell fate... Show details
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