PDPK1
Full Name: 3-phosphoinositide dependent protein kinase 1
Synonyms: PDK1, hPDK1, PkB kinase like gene 1...
SpeciesHuman
Gene ID5170
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Product(s)
Summary
Interaction Network
Pathways
 
 
Available Products
2
Product Product no. Cat. no. List price:
(ENSG00000140992). PCR and sequencing primers for Pyrosequencing analysis of gene-specific CpG methylation after DNA bisulfite conversion (200 reactions; tube format)
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978746 PM00175014 $88.30
(ENSG00000140992). PCR and sequencing primers for Pyrosequencing analysis of gene-specific CpG methylation after DNA bisulfite conversion (200 reactions; tube format)
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978746 PM00175021 $88.30
Laboratory-verified forward and reverse primers for 200 reactions
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335002 EPHS104988
-1A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)01A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)02A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)03A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)04A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)05A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)06A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)07A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)08A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)09A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(-)10A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)11A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)12A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)13A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)14A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)15A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)16A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)19A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1004848
(-)18A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(+)01A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(+)06A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(+)10A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(-)20A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(-)17A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(+)02A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(+)03A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(+)04A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(+)05A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(+)07A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(+)08A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1004848
(+)09A
$236.00
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Pathways containing this gene
41
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Akt is an evolutionarily conserved serine/threonine kinase involved in a wide variety of cellular functions, including proliferation, cell survival, differentiation, glucose mobilization,... Show details
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Sodium transport across the tight epithelia of Na+ reabsorbing tissues such as the distal nephron and colon is the major factor determining total body Na+ levels, and thus, long term blood... Show details
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One of the key functions of catabolic metabolism is to maintain high levels of ATP (Adenosine Triphosphate) and cells rapidly respond to any stress that threatens to lower ATP levels by arresting... Show details
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The ability of multicellular organisms to maintain cellular homeostasis is critically dependent on a balance between cell survival and cell death (apoptosis). The responsiveness of individual... Show details
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The BCR (B-Cell antigen Receptor) plays a critical role in development, survival, and activation of B cells. The BCR is composed of mIg molecules (Membrane Immunoglobulin) and associated... Show details
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Chemokines, or chemotactic cytokines, are a large family of small (6-14 kDa), structurally related proteins that mediate a wide range of biological activities. As a part of normal immune system... Show details
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The cell membranes do not simply serve as barriers to separate the inside of the cell from the outside or to delineate different intracellular compartments. These membranes also serve as a... Show details
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EGF (Epidermal Growth Factor) is a small 53 amino acid residue protein that is involved in normal cell growth, oncogenesis, and wound healing. This protein shows both strong sequential and... Show details
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Protein synthesis in eukaryotic organisms is a complex process that requires cooperation among a large number of polypeptides including ribosomal proteins, modification of enzymes, and... Show details
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The ErbB (Erythroblastic Leukemia Viral Oncogene Homolog) or EGF (Epidermal Growth Factor) family of transmembrane PTKs (Receptor Tyrosine Kinases) plays an important role during the growth and... Show details
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The ErbB tyrosine kinases (epidermal growth factor receptor (EGFR), ErbB2/HER2, ErbB3, and ErbB4) are cell surface growth factor receptors widely expressed in many developing mammalian tissues,... Show details
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The ErbB receptor tyrosine kinases comprise the four members, epidermal growth factor receptor (EGFR)/ErbB1, Her2/ErbB2, ErbB3 and ErbB4. ErbB-family members are known to play critical roles in... Show details
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Erythropoiesis is a major pathway for Erythrocyte production, by which pluripotent Hematopoietic Stem Cells give rise to mature end stage cells via a series of... Show details
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Engagement of integrin receptors with extracellular ligands gives rise to the formation of complex multi-protein structures that link the ECM (Extracellular Matrix) to the cytoplasmic Actin ... Show details
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The ability of the immune system to respond appropriately to foreign antigen is dependent on a delicate balance of activating and inhibitory signals. Although positive signaling is essential for... Show details
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FLT3 (Fms-like Tyrosine Kinase-3), also known as FLK2 (Fetal Liver Kinase-2) and STK1 (human Stem Cell Kinase-1) was originally isolated as a hematopoietic progenitor cell-specific kinase, and... Show details
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The G12 subfamily of heterotrimeric G-Proteins , comprised of the Alpha-subunits G-Alpha12 and G-Alpha13, has been implicated as a signaling component in cellular processes ranging from... Show details
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GPCR (G-Protein-Coupled Receptors) constitute a large and diverse family of proteins whose primary function is to transduce extracellular stimuli into intracellular signals. They are among the... Show details
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G-proteins (Guanine Nucleotide-Binding Proteins) are heterotrimeric proteins that mediate signal transduction between many membrane-bound receptors and intracellular effectors. Traditionally,... Show details
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Sertoli-Germ (Spermatid)-cell interactions affect spermatogenesis at the molecular, cellular and biochemical levels. Germ cell movement within the epithelium is vital because germ cells, if... Show details
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Most aging individuals die from atherosclerosis, cancer, or dementia; but in the oldest old, loss of muscle strength resulting in frailty is the limiting factor for an individuals chances of... Show details
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Embryonic stem (ES) cells have the capacity to proliferate indefinitely in culture while maintaining the ability to differentiate to form any of the cells of the body. This unique combination of... Show details
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Huntingtons disease, also known as Huntington Chorea, is a dominantly inherited Neurodegenerative disorder featuring progressively worsening Chorea, Psychiatric disturbances and Cognitive... Show details
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During immune response, T-cells are optimally activated in secondary lymphoid tissues in order to properly migrate into areas of inflamed tissue. Upon antigen recognition via the... Show details
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Insulin-like growth factor 1 (IGF1) control many biological processes such as cellular metabolism, proliferation, differentiation, and apoptosis. These effects are mediated through ligand... Show details
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IL-4 (Interleukin-4) is a T-Cell derived multifunctional cytokine with a molecular weight of approximately 15 to 19 kD that plays a critical role in the regulation of immune responses. It plays an... Show details
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The ECM (Extracellular Matrix) provides the structural framework for the formation of tissues and organs. The ECM binds to substrate adhesion molecules on the surface of cells and influences... Show details
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Insulin is the major hormone controlling critical energy functions such as glucose and lipid metabolism. Insulin elicits a diverse array of biological responses by binding to its specific receptor... Show details
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Much of the efficiency of the immune system is attributed to the high degree of spatial and temporal organization in the secondary lymphoid organs. Signaling through the LT-BetaR (Lymphotoxin-Beta... Show details
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Cancer cell genotypes are a manifestation of six essential alterations in cell physiology that collectively dictate malignant growth; self-sufficiency in growth signals, insensitivity to... Show details
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Most organisms have evolved mechanisms for efficiently transitioning between anabolic and catabolic states, allowing them to survive and grow in environments in which nutrient availability is... Show details
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One of the most fundamental issues in current biology is how to maintain the critical balance between cell survival and death, both during development and in adulthood. Unrestrained cell division... Show details
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p70S6K is a protein Ser-Thr kinase that phosphorylates the ribosomal S6 subunit, a component of the 40S subunit of eukaryotic ribosomes. It plays a role in protein synthesis and in cell growth... Show details
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The PI3K (Phosphatidylinositde-3-Kinase) family of enzymes regulate diverse biological functions in every cell type by generating lipid second messengers that ultimately results in the mediation... Show details
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PI3Ks (Phosphoinositide-3-Kinases) regulate numerous biological processes, including cell growth, differentiation, survival, proliferation, migration and metabolism. In the immune system, impaired... Show details
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Prl (Prolactin), a multifunctional hormone secreted by the anterior pituitary gland and to a lesser extent by numerous extrapituitary tissues, affects more physiological processes than all other... Show details
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Tumorigenesis is the result of abnormal activation of growth programs in the cells. Most oncogene and tumor suppressor gene products are components of signal transduction pathways that control... Show details
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eIF4 (Eukaryotic Initiation Factor-4) and p70S6K play critical roles in translational regulation. The signaling pathway that regulates p70S6K also regulates the phosphorylation of 4EBP1... Show details
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TREMs (Triggering Receptor Expressed on Myeloid Cells) are a family of recently discovered receptors of the immunoglobulin superfamily, expressed on various cells of the myeloid lineage, which... Show details
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A recurring theme in neurobiology is the role of a set of molecules that support proliferation, differentiation and survival of neurons. These molecules, collectively referred to as neurotrophins,... Show details
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Yersinia pestis, a gram-negative bacillus, which is responsible for causing bubonic plague, is considered by the Center for Disease Control to be one of the top 5 bioterrorist agents. After... Show details
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