RAC3
Full Name: ras-related C3 botulinum toxin substrate 3...
Synonyms: rho family...
SpeciesHuman
Gene ID5881
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Product(s)
Summary
Interaction Network
Pathways
 
 
Available Products
30
Product Product no. Cat. no. List price:
(ENSG00000169750). PCR and sequencing primers for Pyrosequencing analysis of gene-specific CpG methylation after DNA bisulfite conversion (200 reactions; tube format)
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978746 PM00181951 $88.30
(ENSG00000169750). PCR and sequencing primers for Pyrosequencing analysis of gene-specific CpG methylation after DNA bisulfite conversion (200 reactions; tube format)
show details
978746 PM00181958 $88.30
(ENSG00000169750). PCR and sequencing primers for Pyrosequencing analysis of gene-specific CpG methylation after DNA bisulfite conversion (200 reactions; tube format)
show details
978746 PM00181965 $88.30
(ENSG00000169750). PCR and sequencing primers for Pyrosequencing analysis of gene-specific CpG methylation after DNA bisulfite conversion (200 reactions; tube format)
show details
978746 PM00181972 $88.30
Laboratory-verified forward and reverse primers for 200 reactions
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335002 EPHS106441
-1A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)01A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)02A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)03A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)04A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)05A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)06A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)07A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)08A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)09A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)10A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)11A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)12A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)13A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)14A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)20A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)19A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)18A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)17A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)16A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(-)15A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(+)01A
$236.00
ChIP qPCR Primer Assay
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334001 GPH1006111
(+)02A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1006111
(+)03A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1006111
(+)04A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1006111
(+)05A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1006111
(+)06A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1006111
(+)07A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1006111
(+)08A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1006111
(+)09A
$236.00
ChIP qPCR Primer Assay
show details
334001 GPH1006111
(+)10A
$236.00
Configure
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Pathways containing this gene
54
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The Actin family is a diverse and evolutionarily ancient group of proteins that provide the supportive framework to the three-dimensional structure of eukaryotic cells. It provides the forces that... Show details
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Actin Nucleation By ARP-WASP Complex For many cell types, the ability to move across a solid surface is fundamental to their biological function. Certain aspects of cell locomotion, such as the... Show details
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In response to a variety of extracellular stimuli, actin filament assembly at the leading edge of motile cells causes protrusion during cell crawling and chemotaxis, nerve growth and cell... Show details
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PKC (Protein Kinase-C) is a cyclic nucleotide-independent enzyme that phosphorylates serine and threonine residues in many target proteins. PKC plays a pivotal role in mediating cellular responses... Show details
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The vertebrate neuromuscular junction (NMJ) remains the best-studied model for understanding the mechanisms involved in synaptogenesis, due to its relatively large size, its simplicity of... Show details
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Oxidative stress/Hypoxia is induced by a wide range of environmental factors including UV stress, pathogen invasion (hypersensitive reaction), oxygen shortage, etc. Generation of ROS (Reactive... Show details
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The BCR (B-Cell antigen Receptor) plays a critical role in development, survival, and activation of B cells. The BCR is composed of mIg molecules (Membrane Immunoglobulin) and associated... Show details
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Stmn1 (Stathmin-1) also referred to as Op18 (Oncoprotein-18) is a major regulator of microtubule dynamics. It is an evolutionarily well conserved 17 kDa cytoplasmic phosphoprotein that is highly... Show details
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Human eosinophils are crucial effector cells implicated in a number of chronic inflammatory reactions, associated with bronchial asthma, allergic-inflammatory diseases, and parasitic infections... Show details
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The Chemokine receptor CXCR4 is a 352 amino acid rhodopsin-like GPCR and selectively binds the CXC chemokine Stromal Cell-Derived Factor 1 (SDF-1) also known as CXCL12. This receptor has been... Show details
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The Eph family forms the largest group of RTKs (Receptor Tyrosine Kinases) comprising 14 members in mammals that play critical roles in diverse biological processes during development as well as... Show details
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In numerous processes that are vital for the development and maintenance of organism function, cells must communicate crucial information to respond appropriately to the changing environment. As... Show details
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Adhesion between neighboring epithelial cells is a crucial and tightly controlled process. The integrity of cell-cell contacts is essential for the regulation of electrolyte absorption and for the... Show details
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Engagement of integrin receptors with extracellular ligands gives rise to the formation of complex multi-protein structures that link the ECM (Extracellular Matrix) to the cytoplasmic Actin ... Show details
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The formation of antigen-antibody complexes plays a fundamental role in our immune defense system. Interaction of these complexes with many cells of the immune system results in a variety of... Show details
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The Fc-GammaR (Fc-Gamma Receptors/Immunoglobulin-Gamma Fc Receptors) expressed on hematopoietic cells play a key role in immune defenses by linking humoral and cellular immunity.Fc-GammaR ... Show details
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Phagocytosis is of fundamental importance for a wide diversity of organisms. Phagocytic cells in complex metazoans represent an essential branch of the immune system. Evolution has armed these... Show details
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Neutrophils play an important role in the host defense by invading microbial pathogens. Upon infection neutrophils become activated through interaction with chemo attractants and cytokines. These... Show details
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The G12 subfamily of heterotrimeric G-Proteins , comprised of the Alpha-subunits G-Alpha12 and G-Alpha13, has been implicated as a signaling component in cellular processes ranging from... Show details
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Sertoli-Germ (Spermatid)-cell interactions affect spermatogenesis at the molecular, cellular and biochemical levels. Germ cell movement within the epithelium is vital because germ cells, if... Show details
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Normal mammalian sexual maturation and reproductive functions require the integration and precise coordination of hormones at the hypothalamic, pituitary, and gonadal levels. The hypothalamic GnRH... Show details
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GPCRs (Guanine Nucleotide Binding-Protein Coupled Receptors) comprise large and diverse gene families in fungi, plants, and the animal kingdom. Also termed serpentine receptors, GPCRs are... Show details
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As an axon grows, the growth cone at its advancing edge encounters specific ‘choice points’ at which guidance cues steer specific axons towards their appropriate destinations. Such cues may... Show details
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The ECM (Extracellular Matrix) provides the structural framework for the formation of tissues and organs. The ECM binds to substrate adhesion molecules on the surface of cells and influences... Show details
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Insulin is the major hormone controlling critical energy functions such as glucose and lipid metabolism. Insulin elicits a diverse array of biological responses by binding to its specific receptor... Show details
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Adhesive interactions between cells and ECM (Extracellular Matrix) proteins play a vital role in biological processes, including cell survival, growth, differentiation, migration, inflammatory... Show details
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An essential step in the life cycle of many important pathogenic bacteria is their ability to invade cells that are normally nonphagocytic. Gaining access to an intracellular niche provides... Show details
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Development of a proper immune system requires the selection of lymphocytes expressing a useful repertoire of antigen receptors that can respond to foreign or dangerous antigens but not to self.... Show details
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MAPKs (Mitogen-Activated Protein Kinases) are Serine-threonine protein Kinases that are activated in response to a variety of extracellular stimuli and mediate signal transduction from the cell... Show details
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Protein kinases are ubiquitous enzymes that are able to modulate the activities of other proteins by adding phosphate groups to their tyrosine, serine, or threonine amino acids (phosphorylation).... Show details
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Cancer cell genotypes are a manifestation of six essential alterations in cell physiology that collectively dictate malignant growth; self-sufficiency in growth signals, insensitivity to... Show details
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Most organisms have evolved mechanisms for efficiently transitioning between anabolic and catabolic states, allowing them to survive and grow in environments in which nutrient availability is... Show details
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Directional information is provided to migrating neurons and growth cones in the form of extracellular cues, whose presence, absence, or concentration differential is transduced into effects on... Show details
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One of the most fundamental issues in current biology is how to maintain the critical balance between cell survival and death, both during development and in adulthood. Unrestrained cell division... Show details
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p70S6K is a protein Ser-Thr kinase that phosphorylates the ribosomal S6 subunit, a component of the 40S subunit of eukaryotic ribosomes. It plays a role in protein synthesis and in cell growth... Show details
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PAKs (p21-Activated Protein Kinases) are a growing family of serine/threonine protein kinases, which are activated in response to extracellular signals and regulate cell shape and motility. PAKs... Show details
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Pancreatic carcinoma is one of the most enigmatic and aggressive malignant diseases. Neoplasms of the pancreas encompass a wide spectrum of benign and malignant tumors. Pancreatic adenocarcinoma,... Show details
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Phagocytosis, a central component of the innate immune response, is the process whereby specialised cell types recognise and engulf foreign extracellular material. While lower organisms use... Show details
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Inositol lipid-specific PLC (Phospholipase-C) isozymes are key signaling proteins in the cellular action of many hormones, neurotransmitters, growth factors, and other extracellular stimuli. PLC... Show details
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The PI3K (Phosphatidylinositde-3-Kinase) family of enzymes regulate diverse biological functions in every cell type by generating lipid second messengers that ultimately results in the mediation... Show details
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An effective immune response depends on the ability of specialized immunocytes to identify foreign molecules and respond by differentiation into mature effector cells. A cell-surface antigen... Show details
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Tumorigenesis is the result of abnormal activation of growth programs in the cells. Most oncogene and tumor suppressor gene products are components of signal transduction pathways that control... Show details
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Normal cell function, and its contribution to overall physiology, depends on the proper response of cells to extracellular stimulus. Ras, a legendary cellular and biochemical signaling molecule... Show details
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The Rho family of small GTP-binding proteins comprises a group of signaling molecules that are activated by a variety of Growth factors, Cytokines, Adhesion molecules, Hormones, Integrins,... Show details
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Various lipid molecules serve as second messengers for transducing signals from the cell surface to the cell interior and trigger specific cellular responses. Sphingolipids represent a complex... Show details
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The Semaphorins are a family of growth cone guidance molecules, conserved from insects to mammals, which includes proteins strongly implicated in mediating repulsive guidance during... Show details
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The Blood-Testes Barrier (abbreviated as BTB) acts as a physical barrier between the blood vessels and the seminiferous tubules of the testes. This barrier is formed by tight and adherens... Show details
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Bacterial pathogens possess highly specialized adaptive processes that enable their penetration of the host intestinal epithelium and cause disease. Once bound to the epithelial surface, bacteria... Show details
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Hypertrophic cardiomyopathy (HCM) is a monogenic cardiac disease with an autosomal dominant pattern of heritability and different penetrance, with a prevalence in the general population of... Show details
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T-Cells are a subset of lymphocytes that play a large role in the immune response. The TCR (T-Cell Receptor) is a complex of integral membrane proteins that participates in the activation of... Show details
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Nonreceptor PTKs (Protein Tyrosine Kinases) are essential for the development and activation of B-Cells and T-Cells (Ref.1). The Tec kinases represent the second largest family of mammalian... Show details
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The migratory properties of leukocytes or WBCs (White Blood Cells) are indispensable to drive immune responses throughout the body. Leukocytes fall under two categories according to their... Show details
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A recurring theme in neurobiology is the role of a set of molecules that support proliferation, differentiation and survival of neurons. These molecules, collectively referred to as neurotrophins,... Show details
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Yersinia pestis, a gram-negative bacillus, which is responsible for causing bubonic plague, is considered by the Center for Disease Control to be one of the top 5 bioterrorist agents. After... Show details
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