QIAGEN provides stainless steel beads and tungsten carbide beads for use in sample disruption with TissueLyser systems. High-speed shaking of sample material and a single bead in a Collection Microtube or 2 ml microcentrifuge tube for a few minutes allows rapid and efficient disruption of the sample. Guidelines for use of stainless steel beads and tungsten carbide beads are provided in the handbook supplied with the TissueLyser instrument. For easy dispensing of beads into tubes, TissueLyser Bead Dispensers are available.
Tungsten Carbide beads react with lysis buffers e.g. buffer RLT, RLT Plus and QIAzol lysis reagent, used in QIAGEN’s RNA extraction kits. Therefore we do not recommend using the Tungsten Carbide beads with our RNA extraction kits.