COSMIC

COSMIC is the gold standard database for somatic mutation information.

COSMIC, the Catalogue Of Somatic Mutations In Cancer is the most detailed and comprehensive resource for exploring the effect of somatic mutations in human cancer. In addition to coding mutations, COSMIC covers all the genetic mechanisms by which somatic mutations promote cancer, including non-coding mutations, gene fusions, copy-number variants and drug-resistance mutations. It includes the Cancer Gene Census (CGC), an expert-curated library of cancer-driving genes in humans, and a standard in cancer genetics across basic research, medical reporting and pharmaceutical development.

COSMIC data are carefully selected, collected and standardized through manual curation by scientific experts, ensuring high quality, accuracy and descriptive data capture.

COSMIC data is available as a download, ready for you to integrate into your current pipelines and tools. You also will get access to any updates released during the one-year subscription period, as well as access to our support team.

Discover potential drug targets and biomarkers for cancer. Improve cohort selection for clinical trials. Identify driver mutations and relevant genes to support patient diagnosis.