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The 96-Well Magnet Type A can be used with Ni-NTA Magnetic Agarose Beads for high-throughput 6xHis-tagged–protein magnetocapture assays or purification procedures. The magnet consists of an array of 24 powerfully magnetic NdFeB (neodymium-iron-boron) rods that fit between the wells of commercially available 96-well microplates. Each magnetic rod attracts the beads in four adjacent wells to the sides of the wells and keeps the beads in place while the buffer is exchanged. The magnetic beads are very easily resuspended in buffer once removed from the magnet, allowing thorough washing and elution. Appropriate flat-bottom microplates (96-Well Microplates FB) are supplied with the 96-Well Magnet Type A.