Enabling justice and closure

Streamline your sexual assault case workflow

Sexual assault victims often do not get the necessary closure due to the lack of informative and conclusive results from challenging DNA evidence. Issues related to DNA mixtures, degraded and low levels of DNA, PCR inhibitors, and even available laboratory resources to process samples in a timely manner, can all impede successful completion of necessary casework. 

QIAGEN is partnering with forensic scientists worldwide and enabling justice by streamlining sexual assault sample analysis:

•  Automate differential extraction on the QIAcube Connect
•  Identify samples that will succeed using the novel Investigator Casework GO! Kit
•  Improve downstream assay decision making using the Investigator Quantiplex Pro RGQ Kit
•  Confirm the presence of seminal fluid/sperm using the PyroMark Q48 Autoprep


April is Sexual Assault Awareness Month

I Ask champions the message that asking for justice and closure is the fundamental right of every victim or survivor. This April, we want to raise awareness and commit to continue empowering forensic scientists to tackle specialized, challenging sexual assault investigations with the aim of bringing closure to the survivors.

Efficient separation of sexual assault samples

Effective lysis and careful separation of the sperm and epithelial fractions are essential to achieve the best possible results in downstream quantification and DNA profiling. Our specially designed differential wash protocols on the QIAcube (now QIAcube Connect) rise to meet this challenge, helping you get the most out of difficult samples.

Watch the video to hear Maria Cownan, Criminalist II, City and County of San Francisco share her experience using the QIAcube for sexual assault sample processing

Rapid, reliable quantification of total human and male DNA

Quantification of your samples prior to downstream STR typing confirms that sufficient DNA is present for further testing, indicates whether it contains inhibitors, and predicts the success of your STR analyses. The newly developed Investigator Quantiplex Pro RGQ Kit provides reliable information on the degradation status of both male and human DNA using quantitative real-time PCR. It is particularly beneficial when analyzing sexual assault samples where low levels of the male perpetrator’s DNA could be highly degraded in a high background of a female victim's DNA. 

Confident tissue source identification in forensic casework 

Attribution of a DNA profile to a specific cell or tissue type can enable forensic investigators to address source-level questions often posed by the judiciary. Recent research efforts have led to the development of new assays for identification of body fluids based on epigenetic markers such as DNA methylation. Analysis of DNA methylation by Pyrosequencing on the PyroMark Q48 Autoprep enables accurate and reliable sperm identification in sexual assault samples.

DNA methylation – leading into the future of forensic casework analysis 

Biological samples collected at crime scenes have potential to be used for predicting the age of the individuals from whom the samples originated. In cases with no DNA profile match against a database, such information could be critical for providing additional intelligence for criminal investigations. Determining whether the biological material originates from semen can be extremely informative in sexual assault cases.

Looking for more solutions to free up your time?

Our new workflow demo tool provides a comprehensive overview of our latest generation of powerful chemistries and automated solutions for forensic casework.