JAK2 MutaQuant Kits is a ready-to-use kit for the detection and quantification of the JAK2 V617F/G1849T somatic mutation due to a single nucleotide polymorphism (SNP) in genomic DNA extracted from peripheral blood of subjects with suspected myeloproliferative neoplasm (MPN) (see figure JAK2 mutation site identification
). The kit provides high levels of sensitivity and reproducibility. The ipsogen
JAK2 MutaQuant Kit provides 4 plasmid standard dilutions for mutant JAK2 V617F and 4 for the wild-type JAK2 allele. Use of the standards enables accurate quantification of transcripts. Results are expressed as a percent of JAK2 V617F in total JAK2.