- Replaces syringe-and-needle homogenization
- Reduces loss of sample material
- Eliminates cross-contamination between samples
- Filters out insoluble debris and reduces viscosity
The QIAshredder homogenizer consists of a unique biopolymer-shredding system in a microcentrifuge spin-column format. Cell or tissue lysate is loaded onto the QIAshredder homogenizer placed in a collection tube and centrifuged. The homogenized lysate is then collected. In general, similar yields and quality of RNA are obtained as with rotor–stator homogenization (see figure "
Comparison of RNA yields").