Locked Nucleic Acids (LNA) Knowledge Center

ILLU_0982_miRNA_Biogenesis_01
Detect and discriminate short or closely related sequences with ease
LNA oligos exhibit unprecedented thermal stability when hybridized to their complement. This much higher affinity – compared to traditional DNA or RNA oligos – helps overcome the difficulties of studying very short sequences. LNA oligos have greatly improved, and in many cases enabled, specific and sensitive detection of non-coding RNA and other small RNA molecules. Beyond RNA, these powerful tools are ideal for detecting low-abundance, short or highly similar targets in many other research applications. QIAGEN and Exiqon have merged our expertise to provide a comprehensive portfolio of LNA-enhanced research tools. Read on and learn how you can use these to gain more insights from your experiments.