Using methylation patterns to determine origin of biological material and age


In this QIAGEN sponsored webinar, our guest speakers from the San Francisco Police Department (SFPD) Crime Lab and Florida International University (FIU) discuss their research on the potential of epigenetic methylation as a procedure for body fluid identification and age estimation from DNA left at crime scenes. Several approaches have been studied, including an analysis of methyl array data and an initial validation of procedures such as pyrosequencing and real-time PCR. The presentation focuses on a number of tissue-specific epigenetic markers for body fluid and age determination with a promise of future integration of these markers into the forensic lab due to the simplicity of analysis and the ease of application.

Bruce R. McCord, Ph.D.

Bruce R. McCord is a Professor of Analytical and Forensic Chemistry at Florida International University. He received a BS in Chemistry with honors from the College of William and Mary, and a Ph.D. in Analytical Chemistry from the University of Wisconsin-Madison. His research interests involve forensic genetics, toxicology and explosives residue detection. Bruce has published over 100 peer reviewed papers and book chapters and his research has been supported by the National Institute of Justice, the National Science Foundation, TSWG and the Department of Homeland Security .
Dr. Ruth Kläver, Scientist Product Development, QIAGEN

Dr. Ruth Kläver studied Biology (B.Sc.) and Molecular Biomedicine (M.Sc.) at the Universities of Marburg (Germany), Münster (Germany) and Salamanca (Spain). She performed her PhD studies at the Centre of Reproductive Medicine and Andrology in Münster as a member of the joint graduate school CEDAD-IMPRS. Her research focused on epigenetics in male germ cells, and after finishing her PhD in December 2013 she continued her research projects on a postdoctoral position.

In August 2014 Dr. Ruth Kläver joined the Product Development department of QIAGEN. She was heading sub-projects in the development of the PyroMark Q48 Autoprep. In addition, she is supporting life cycle management of the PyroMark product portfolio. Since December 2015 she is working in the field of single cell analysis and is responsible for the development of the QIAscout instrument.