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QuantiFERON-TB Gold Plus (QFT-Plus)

For use as an aid in the detection of Mycobacterium tuberculosis (TB) infection
  • Higher sensitivity at >95%
  • Highest specificity of any test for tuberculosis infection
  • Innovative CD8+ T-cell technology
  • Robust and reliable results
  • Improvements in TB test formulation and manufacturing
QuantiFERON-TB Gold Plus detects interferon γ (IFNγ) response by enzyme-linked immunosorbent assay (ELISA) to provide the most accurate TB test kit for TB infection.

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Cat No./ID: 622120
QuantiFERON-TB Gold Plus 2 Plate Kit ELISA
Microplate Strips; IFN-gamma Standard, lyophilized; Green Diluent; Conjugate 100x Concentrate, lyophilized; Wash Buffer 20x Concentrate; Enzyme Substrate Solution; Enzyme Stopping Solution
Cat No./ID: 622222
QFT-Plus Blood Collection Tubes Single Patient Pack (10 tests)
10 QFT-Plus Blood Collection Tubes packs, each including: Nil, TB1, TB2, and Mitogen tubes
Cat No./ID: 622526
QFT-Plus Blood Collection Tubes (200)
QFT-Plus Blood Collection Tubes: Nil, TB1, TB2, and Mitogen tubes (50 each)
Cat No./ID: 622822
QFT-Plus Ref Lab Pack
QFT-Plus Ref Lab Pack
Cat No./ID: 622912
QFT-Plus SPP + BD Needles and Holders
Includes: 10 boxes of QFT-Plus Tubes + 1 bag of Becton Dickenson 10 needles and 10 holders
Cat No./ID: 622914
QFT-Plus HA SPP+BD Needles and Holders
Includes: 10 boxes of QFT-Plus HA Tubes + 1 bag of Becton Dickenson 10 needles and 10 holders
Cat No./ID: 622916
QFT-Plus SPP+BD Luer Needle Holder
Includes: 10 boxes of QFT-Plus Tubes + 1 bag of 10 of Becton Dickenson luer lock needle holders
QuantiFERON-TB Gold Plus is an indirect test for M. tuberculosis infection (including disease) and is intended for use in conjunction with risk assessment, radiography, and other medical and diagnostic evaluations.
QuantiFERON-TB Gold Plus (QFT-Plus) ELISA Package Insert. 1083163 Rev. 02. February 2015.
The QuantiFERON-TB Gold Plus (QFT-Plus) is intended for in vitro diagnostic use in Europe.

Product Details

QFT-Plus is an improved version of the current QuantiFERON-TB Gold test, using the same test principle, procedure and reliable technology. This TB blood test is highly accurate, with sensitivity of 95.3% and specificity of 97.6%. 

QFT-Plus is an IFNγ release assay, commonly known as an IGRA, and measures the cell-mediated immune response to specific TB antigens in whole blood. Patients may be tested in a single patient visit, with objective results.

Additional clinical value comes from the exclusive TB-specific antigens that elicit CD4+ and CD8+ T-cell responses. This new test format, combined with improvements in tuberculosis test formulation and manufacturing, means more robust and reliable assay performance.


QuantiFERON is a powerful Premolecular diagnostic technology that delivers results with high sensitivity, enabling the detection of M. tuberculosis infection even in early or latent stages. The QFT-Plus test employs a peptide cocktail simulating ESAT-6 and CFP-10 proteins to stimulate cells in heparinized whole blood. Detection of IFN-γ by ELISA is used to identify in vitro responses to these peptide antigens, which are associated with M. tuberculosis infection. Premolecular Diagnostics that employ QuantiFERON technology, like QFT-Plus, are able to detect infection at an earlier stage than is possible with DNA- and RNA-based molecular diagnostics.

The QFT-Plus test is a straightforward laboratory TB blood test that involves the following steps:
  1. Collect whole blood in a standard blood collection tube, or specialized QFT-Plus Blood Collection Tubes.
  2. Incubate for 16 to 24 hours at 37°C.
  3. Detect released IFNγ in harvested plasma by ELISA.
  4. Analyze results using QFT-Plus Analysis Software.

QFT-Plus has 4 blood collection tubes: Nil, TB1, TB2, and Mitogen. Collect 1 ml of whole blood into each tube.

QFT-Plus can be used in many clinical and public health settings, including screening for healthcare workers, children at high-risk of exposure to TB, immigrants, military personnel, those in correctional facilities, and homeless individuals.
QFT-Plus can also be used in at-risk populations, such as:
  • People taking certain medications (e.g., TNF alpha inhibitors)
  • Patients with weakened immune systems
  • Elderly patients
Analysis software for QuantiFERON-TB Gold Plus is available at www.QuantiFERON.com.

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