text.skipToContent text.skipToNavigation

Cignal Reporter Assay Kits

For rapid, sensitive, and quantitative assessment of signal transduction pathway activation

  • Rapid analysis of signal transduction pathway regulation
  • Exceptional sensitivity and specificity
  • Transfection-ready constructs
  • Includes positive and negative controls
  • Real-time live cell quantification (GFP format)

Cignal Reporter Assays provided in the Cignal Reporter Assay Kit enable rapid, sensitive, and quantitative assessment of signal transduction pathway activation by measuring the activities of downstream transcription factors. Two reporter systems are available: dual-luciferase format and GFP format.

Advanced search settings



Species:
Products
Product Product no. Cat. no. List price:
 
 
Show details
    varies
Can't order online?
To place an order via phone, email or for requesting a quote, please provide the product’s name, number and catalog number.
Available Controls
Configure
Product Product no. Cat. no. List price:
 
 
Show details
    varies
Can't order online?
To place an order via phone, email or for requesting a quote, please provide the product’s name, number and catalog number.

Cignal Reporter Assay Kits are intended for molecular biology applications. These products are not intended for the diagnosis, prevention, or treatment of a disease.


0
TNFα activates NFkB signaling activity in a dose-dependent manner.
293 H cells were transfected with Cignal NFkB Reporter Assay, negative or positive control. After 24 hours, cells were treated with different doses of hTNFα for a further 24 hours. Dual-luciferase assays were performed, and reporter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and standard deviation is shown.
1
Assessing RNA interference phenotypes.

Cignal p53 Reporter Assays showed that p53 siRNA treatment abolished p53 transcription activity. HCT 116 cells were transfected with p53 reporter, negative control, and positive control, together with p53 siRNA or negative control siRNA. Dual-luciferase assays were performed. Reporter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and the standard deviation is shown.

2
Assessing overexpression phenotypes.

Cignal RBP-Jκ Reporter Assay showed upregulation of Notch signaling activity after overexpression of activated Notch1. 293 H cells were transfected with RBP-Jκ reporter, negative control, and positive control. After 24 hours, cells were infected with 100 MOI of recombinant adenoviruses expressing activated Notch1 (Ad-NICD) or 100 MOI of recombinant adenovirus expressing GFP (Ad-GFP) for another 18 hours. Dual-luciferase assays were performed. Reporter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and the standard deviation is shown.

3
Verification of small molecule drug candidate.

Cignal Retinoic Acid Response Element (RARE) Reporter Assay reported elevated retinoic acid receptor pathway activity after the treatment of all trans-retinoic acid (ATRA). CHO-K1 cells were transfected with RARE reporter, negative control, and positive control. After 16 hours, medium was changed to assay medium. After 24 hours, cells were treated with 1 µM all trans-rectinoic acid (ATRA) for 6 hours. Dual-luciferase assay was performed, and promoter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and the standard deviation is shown.

4
Cignal Reporter Assay shows that hTNFa activated NFkB signaling pathway.
293 H cells were transfected with the Cignal NFkB-GFP Reporter Assay or negative control. After 16 hours, medium was changed to assay medium. After 24 hours, cells were treated with 10 ng/ml TNFα. After 18 hours, medium was removed from the wells and fluorescence activity was measured using a fluorometer. The fluorescence activity present in treated and nontreated negative control wells was subtracted from the fluorescence activity in treated and nontreated Cignal NFkB-GFP Reporter Assay wells and relative fluorescence activities expressed as arbitrary units. Experiments were performed in triplicate and the standard deviations are shown.
5
Cignal Reporter Assay measures activation of serum response factor (SRF) transcription activity.

293 H cells were transfected with the Cignal SRF-GFP Reporter Assay or negative control. After 16 hours, medium was changed to assay medium. After 24 hours, cells were treated with 10 ng/ml PMA and 10% serum. After 18 hours, medium was removed from the wells and fluorescence activity was measured using a fluorometer. The fluorescence activity present in treated and nontreated negative control wells was subtracted from the fluorescence activity in treated and nontreated Cignal SRF-GFP Reporter Assay wells and relative fluorescence activities expressed as arbitrary units. Experiments were performed in triplicate and the standard deviations are shown.

6
Cignal Reporter Assay procedure.
7
Cignal Reporter Assay principle.
Performance
Principle

Cignal Reporter Assays consist of multiple repeats of a specific transcription factor’s binding site and basic promoter elements to drive the expression of a reporter gene (firefly luciferase or GFP). These reporters are powerful tools in functional genomics and drug discovery for assessing pathway activity. When the pathway is activated or inhibited by a drug candidate, gene knockdown, overexpression, or peptide, luciferase or GFP reporter activity is modulated and can be measured quantitatively and rapidly (see figure "Cignal Reporter Assay principle"). The Cignal Reporter Assays are available as transfection-ready constructs utilizing two reporter systems: the dual-luciferase reporter or the GFP reporter (see flowchart "Cignal Reporter Assay procedure").

The dual-luciferase format is an end-point assay providing unsurpassed sensitivity, specificity, and signal-to-noise ratios. This format is available for all Cignal Reporter Assays. Each assay includes a pathway-focused transcription factor reporter and a noninducible negative control, as well as luciferase and GFP positive controls.

The GFP format is an outstanding method for monitoring live cell pathway regulation, with single cell resolution. It includes a pathway-focused transcription factor reporter and positive and negative controls.

Procedure

Cignal Reporter Assays include a preformulated, transfection-ready pathway reporter (dual-luciferase or GFP), plus a positive and negative control. The inducible pathway reporter and noninducible negative control are transfected and subjected to experimental treatments in parallel.

Dual-luciferase

Dual-luciferase results are calculated for each transfectant. The change in the activity of each signaling pathway is determined by comparing the normalized luciferase activities of the reporter in treated versus untreated transfectants. The identically treated negative control transfectants serve as a specificity control. The positive control serves as a control for transfection efficiency, by monitoring firefly luciferase and Renilla expression.

GFP

GFP expression is quantified using a flow cytometer, fluorescence microscope, or fluorometer. The change in the activity of each signaling pathway is determined by comparing the GFP activities in treated versus untreated transfectants. The identically treated negative control transfectants serve as a specificity control. The positive control serves as a control for transfection efficiency, by monitoring GFP expression from the constitutively expressing CMV-GFP reporter.

Applications

Cignal Reporter Assays are powerful tools in functional genomics, proteomics, and drug discovery for assessing the biological impact of pathway inhibition or activation with siRNAs, proteins, and small molecule compounds.

You are not authorized to download the resource

Brochures & Guides (1)
For cell-based analysis of pathway signaling activity
Show details
Kit Handbooks (1)
Transfection Protocols (2)
Search for transfection data by nucleic acid, cell line, and transfection reagent. Our database contains data from researchers like yourself who have shared their experimental results with us.
View
Transfection protocols for specific cell types and plate formats that save you the time and effort of adapting existing protocols to fit your requirements. Simply select the cell type, nucleic acid, and culture format to receive a QIAGEN transfection protocol to print out or download in convenient PDF format.
View
fragment fix placeholder
SP1 Reporter Assay Kit Cignal Reporter Assay Kits
Introduction
The Cignal SP1 Reporter Assay Kit is designed to measure the transcriptional activity of SP1 (Specificity Protein 1). SP1 is a "glutamine-rich" transcriptional activator that recognizes 5’-GGGGCGGGGC-3’ and closely related sequences, these binding sites are referred to as GC boxes. The SP1 reporter is a mixture of a SP1-responsive luciferase construct and a constitutively expressing Renilla element (40:1). The SP1-responsive luciferase construct encodes the firefly luciferase reporter gene under the control of a minimal (m)CMV promoter and tandem repeats of the GC box transcriptional response element. The number of response elements and the intervening sequence between these response elements has been experimentally optimized to maximize the signal to noise ratio. The SP1 reporter construct monitors both increases and decreases in the transcriptional activity of SP1. The constitutively expressing Renilla construct encodes the Renilla luciferase reporter gene under the control of a CMV immediately early enhancer/promoter and acts as an internal control for normalizing transfection efficiencies and monitoring cell viability. Using a simple dual-luciferase assay, the activity of SP1 can be easily measured in response to various treatments, such as gene knockdown, over-expression, and chemical compounds on those pathways.
CCS-6027L

The Cignal SP1 Reporter Assay shows SP1 transcription activity. HeLa cells were transfected with the Cignal SP1 Reporter, negative control, and positive control (for the transfection protocol, refer to the Cignal Reporter Assay Handbook). After 4 hours of transfection, medium was changed to growth medium. After 24 hours of transfection, cells were treated with 10 ng/ml or 100 ng/ml Trichostatin A for 18 hours. A dual-luciferase assay was performed, and promoter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate, and the standard deviation is indicated.
Name Cignal SP1 Reporter (luc) Kit (CCS-6027L)
Official symbol TGFB1 [Human]
Official name transforming growth factor, beta 1
Species Human (Homo sapiens)
Entrez Gene ID 7040
Transcript(s) for this gene NM_000660 (2583 bp), ENST00000600196, ENST00000221930
Official symbol Tgfb1 [Mouse]
Official name transforming growth factor, beta 1
Species Mouse (Mus musculus)
Entrez Gene ID 21803
Transcript(s) for this gene NM_011577 (2191 bp), ENSMUST00000171757
Official symbol Tgfb1 [Rat]
Official name transforming growth factor, beta 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 59086
Transcript(s) for this gene NM_021578 (1482 bp)
Official symbol NFYA [Human]
Official name nuclear transcription factor Y, alpha
Species Human (Homo sapiens)
Entrez Gene ID 4800
Transcript(s) for this gene NM_002505 (6236 bp), NM_021705 (6149 bp), ENST00000341376, ENST00000353205
Official symbol Nfya [Mouse]
Official name nuclear transcription factor-Y alpha
Species Mouse (Mus musculus)
Entrez Gene ID 18044
Transcript(s) for this gene NM_001110832 (3728 bp), NM_010913 (3641 bp), ENSMUST00000163066, XM_006523791 (3789 bp), XM_006523792 (3789 bp), XM_006523793 (3786 bp), XM_006523794 (3774 bp), XM_006523795 (3768 bp), XM_006523796 (3687 bp)
Official symbol Nfya [Rat]
Official name nuclear transcription factor-Y alpha
Species Rat (Rattus norvegicus)
Entrez Gene ID 29508
Transcript(s) for this gene NM_012865 (1415 bp), XM_006244409 (3544 bp), XM_006244410 (3540 bp), XM_006244411 (3534 bp), XM_006244412 (3531 bp), XM_006244413 (3452 bp), XM_008766839 (3440 bp)
Official symbol VEGFA [Human]
Official name vascular endothelial growth factor A
Species Human (Homo sapiens)
Entrez Gene ID 7422
Transcript(s) for this gene NM_001025366 (3677 bp), NM_001025367 (3608 bp), NM_001025368 (3554 bp), NM_001025369 (3519 bp), NM_001025370 (3422 bp), NM_001033756 (3488 bp), NM_001171622 (3392 bp), NM_001171623 (3677 bp), NM_001171624 (3626 bp), NM_001171625 (3608 bp), NM_001171626 (3554 bp), NM_001171627 (3519 bp), NM_001171628 (3422 bp), NM_001171629 (3488 bp), NM_001171630 (3392 bp), NM_001204384 (3494 bp), NM_001204385 (3494 bp), NM_003376 (3626 bp), ENST00000518538, NM_001287044 (2569 bp), ENST00000230480, ENST00000324450, ENST00000372055, ENST00000372064, ENST00000372067, ENST00000372077, ENST00000413642, ENST00000417285, ENST00000425836, ENST00000457104, ENST00000482630, ENST00000518689, ENST00000518824, ENST00000520948, ENST00000523125, ENST00000523873, ENST00000523950, ENST00000611736, ENST00000615393, ENST00000617771, ENST00000621747
Official symbol Vegfa [Mouse]
Official name vascular endothelial growth factor A
Species Mouse (Mus musculus)
Entrez Gene ID 22339
Transcript(s) for this gene NM_001025250 (3547 bp), NM_001025257 (3343 bp), NM_001110266 (2857 bp), NM_001110267 (2785 bp), NM_001110268 (2653 bp), NM_009505 (3475 bp), ENSMUST00000150327, NM_001287056 (3547 bp), NM_001287057 (3475 bp), NM_001287058 (3343 bp), NM_001317041 (3475 bp)
Official symbol Vegfa [Rat]
Official name vascular endothelial growth factor A
Species Rat (Rattus norvegicus)
Entrez Gene ID 83785
Transcript(s) for this gene NM_001110333 (3474 bp), NM_001110334 (3342 bp), NM_001110335 (2616 bp), NM_001110336 (2544 bp), NM_031836 (3546 bp), NM_001287107 (3546 bp), NM_001287108 (3474 bp), NM_001287110 (3342 bp), NM_001287111 (3414 bp), NM_001287112 (3414 bp), NM_001287113 (3425 bp), NM_001287114 (3293 bp), NR_105011 (0 bp)
Official symbol HDAC1 [Human]
Official name histone deacetylase 1
Species Human (Homo sapiens)
Entrez Gene ID 3065
Transcript(s) for this gene NM_004964 (2091 bp), ENST00000490081, ENST00000482310, ENST00000463172, ENST00000373548
Official symbol Hdac1 [Mouse]
Official name histone deacetylase 1
Species Mouse (Mus musculus)
Entrez Gene ID 433759
Transcript(s) for this gene NM_008228 (1971 bp), XM_485447 (2024 bp), ENSMUST00000150105, XM_006537010 (1838 bp), XM_011240571 (1803 bp)
Official symbol Hdac1 [Rat]
Official name histone deacetylase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 297893
Transcript(s) for this gene NM_001025409 (2035 bp), XM_216349 (1987 bp)
Official symbol Cdkn1a [Mouse]
Official name cyclin-dependent kinase inhibitor 1A (P21)
Species Mouse (Mus musculus)
Entrez Gene ID 12575
Transcript(s) for this gene NM_001111099 (1943 bp), NM_007669 (1913 bp)
Official symbol Kdr [Mouse]
Official name kinase insert domain protein receptor
Species Mouse (Mus musculus)
Entrez Gene ID 16542
Transcript(s) for this gene NM_010612 (5464 bp), XM_984991 (3861 bp), ENSMUST00000149573, XM_011240817 (5586 bp)
Official symbol KDR [Human]
Official name kinase insert domain receptor (a type III receptor tyrosine kinase)
Species Human (Homo sapiens)
Entrez Gene ID 3791
Transcript(s) for this gene NM_002253 (6055 bp), ENST00000512566, ENST00000263923
Official symbol Trp53 [Mouse]
Official name transformation related protein 53
Species Mouse (Mus musculus)
Entrez Gene ID 22059
Transcript(s) for this gene NM_001127233 (1877 bp), NM_011640 (1781 bp), ENSMUST00000147512, XM_006533157 (2157 bp), XM_006533158 (1843 bp)
Official symbol TP53 [Human]
Official name tumor protein p53
Species Human (Homo sapiens)
Entrez Gene ID 7157
Transcript(s) for this gene NM_000546 (2591 bp), NM_001126112 (2588 bp), NM_001126113 (2651 bp), NM_001126114 (2724 bp), NM_001126115 (2271 bp), NM_001126116 (2404 bp), NM_001126117 (2331 bp), NM_001126118 (2708 bp), NM_001276695 (2651 bp), NM_001276696 (2724 bp), NM_001276697 (2271 bp), NM_001276698 (2404 bp), NM_001276699 (2331 bp), NM_001276760 (2591 bp), NM_001276761 (2588 bp), ENST00000574684, ENST00000269305, ENST00000359597, ENST00000413465, ENST00000420246, ENST00000445888, ENST00000455263, ENST00000504290, ENST00000504937, ENST00000510385, ENST00000610292, ENST00000610538, ENST00000610623, ENST00000615910, ENST00000617185, ENST00000618944, ENST00000619186, ENST00000619485, ENST00000620739, ENST00000622645
Official symbol Tp53 [Rat]
Official name tumor protein p53
Species Rat (Rattus norvegicus)
Entrez Gene ID 24842
Transcript(s) for this gene NM_030989 (1792 bp), XM_006246594 (2185 bp), XM_006246595 (2542 bp), XM_008767773 (1321 bp)
Official symbol Yy1 [Mouse]
Official name YY1 transcription factor
Species Mouse (Mus musculus)
Entrez Gene ID 22632
Transcript(s) for this gene NM_009537 (2324 bp), ENSMUST00000126912, XM_006515820 (1271 bp)
Official symbol YY1 [Human]
Official name YY1 transcription factor
Species Human (Homo sapiens)
Entrez Gene ID 7528
Transcript(s) for this gene NM_003403 (3159 bp), ENST00000554579, ENST00000262238
Official symbol Yy1 [Rat]
Official name YY1 transcription factor
Species Rat (Rattus norvegicus)
Entrez Gene ID 24919
Transcript(s) for this gene NM_173290 (1236 bp), XM_001069615 (5408 bp), XM_006240537 (2275 bp)
Official symbol Col1a1 [Rat]
Official name collagen, type I, alpha 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 29393
Transcript(s) for this gene NM_053304 (5843 bp), XM_001081230 (5862 bp), XM_213440 (5862 bp)
Official symbol COL1A1 [Human]
Official name collagen, type I, alpha 1
Species Human (Homo sapiens)
Entrez Gene ID 1277
Transcript(s) for this gene NM_000088 (5927 bp), ENST00000511732, ENST00000486572, XM_005257058 (5660 bp), XM_005257059 (5012 bp), XM_006721703 (4598 bp), ENST00000225964
Official symbol Col1a1 [Mouse]
Official name collagen, type I, alpha 1
Species Mouse (Mus musculus)
Entrez Gene ID 12842
Transcript(s) for this gene NM_007742 (5946 bp), ENSMUST00000148593
Official symbol Lhcgr [Rat]
Official name luteinizing hormone/choriogonadotropin receptor
Species Rat (Rattus norvegicus)
Entrez Gene ID 25477
Transcript(s) for this gene NM_012978 (2902 bp)
Official symbol LHCGR [Human]
Official name luteinizing hormone/choriogonadotropin receptor
Species Human (Homo sapiens)
Entrez Gene ID 3973
Transcript(s) for this gene NM_000233 (3093 bp), ENST00000477576, XM_005264309 (1370 bp), XM_006712015 (1433 bp), ENST00000294954, ENST00000401907, ENST00000403273, ENST00000405626
Official symbol Lhcgr [Mouse]
Official name luteinizing hormone/choriogonadotropin receptor
Species Mouse (Mus musculus)
Entrez Gene ID 16867
Transcript(s) for this gene NM_013582 (2553 bp), XM_006523719 (2981 bp), XM_006523720 (2906 bp), XM_006523721 (2903 bp), XM_006523722 (2831 bp), XM_006523723 (2678 bp), XM_006523724 (2621 bp), XM_006523725 (2625 bp), XM_006523726 (1289 bp), XM_006523727 (1045 bp)
Official symbol Nfyc [Rat]
Official name nuclear transcription factor-Y gamma
Species Rat (Rattus norvegicus)
Entrez Gene ID 25337
Transcript(s) for this gene NM_012866 (1967 bp), XM_006238785 (1914 bp)
Official symbol NFYC [Human]
Official name nuclear transcription factor Y, gamma
Species Human (Homo sapiens)
Entrez Gene ID 4802
Transcript(s) for this gene NM_001142587 (2102 bp), NM_001142588 (2162 bp), NM_001142589 (1991 bp), NM_001142590 (2380 bp), NM_014223 (2105 bp), ENST00000525349, XM_005270891 (2212 bp), XM_005270893 (2339 bp), XM_005270894 (2454 bp), XM_005270895 (2591 bp), XM_005270896 (2397 bp), XM_006710656 (2664 bp), XM_006710657 (2362 bp), XM_006710658 (2534 bp), XM_006710659 (2510 bp), XM_006710660 (2279 bp), XM_006710661 (2282 bp), XM_006710662 (2222 bp), ENST00000308733, ENST00000372651, ENST00000372652, ENST00000372653, ENST00000372654, ENST00000425457, ENST00000427410, ENST00000440226, ENST00000447388, ENST00000456393, ENST00000620728
Official symbol Nfyc [Mouse]
Official name nuclear transcription factor-Y gamma
Species Mouse (Mus musculus)
Entrez Gene ID 18046
Transcript(s) for this gene NM_001048168 (1917 bp), NM_008692 (1990 bp), NM_001277095 (1876 bp), ENSMUST00000148081, XM_006502846 (2002 bp), XM_006502847 (1773 bp), XM_006502848 (1769 bp), XM_006502849 (1913 bp), XM_006502850 (1891 bp), XM_006502851 (1796 bp), XM_006502852 (902 bp), XM_006502853 (1982 bp)
Official symbol Cdkn1a [Rat]
Official name cyclin-dependent kinase inhibitor 1A
Species Rat (Rattus norvegicus)
Entrez Gene ID 114851
Transcript(s) for this gene NM_080782 (1894 bp), XM_006256128 (1937 bp)
Official symbol Sod2 [Rat]
Official name superoxide dismutase 2, mitochondrial
Species Rat (Rattus norvegicus)
Entrez Gene ID 24787
Transcript(s) for this gene NM_017051 (2090 bp)
Official symbol SOD2 [Human]
Official name superoxide dismutase 2, mitochondrial
Species Human (Homo sapiens)
Entrez Gene ID 6648
Transcript(s) for this gene NM_000636 (1593 bp), NM_001024465 (1035 bp), NM_001024466 (918 bp), ENST00000541573, ENST00000337404, ENST00000367054, ENST00000367055, ENST00000444946, ENST00000452684, ENST00000538183, ENST00000546087
Official symbol Sod2 [Mouse]
Official name superoxide dismutase 2, mitochondrial
Species Mouse (Mus musculus)
Entrez Gene ID 20656
Transcript(s) for this gene NM_013671 (3824 bp)
Official symbol Nfyb [Mouse]
Official name nuclear transcription factor-Y beta
Species Mouse (Mus musculus)
Entrez Gene ID 18045
Transcript(s) for this gene NM_010914 (2552 bp), ENSMUST00000145561, ENSMUST00000143749, XM_006513336 (1089 bp), XM_006513337 (630 bp)
Official symbol NFYB [Human]
Official name nuclear transcription factor Y, beta
Species Human (Homo sapiens)
Entrez Gene ID 4801
Transcript(s) for this gene NM_006166 (3482 bp), ENST00000550881, XM_005268908 (2537 bp), XM_005268909 (2520 bp), XM_005268910 (1987 bp), ENST00000240055, ENST00000551727
Official symbol Nfyb [Rat]
Official name nuclear transcription factor-Y beta
Species Rat (Rattus norvegicus)
Entrez Gene ID 25336
Transcript(s) for this gene NM_031553 (2569 bp), XM_006241196 (2559 bp)
Official symbol Jun [Mouse]
Official name jun proto-oncogene
Species Mouse (Mus musculus)
Entrez Gene ID 16476
Transcript(s) for this gene NM_010591 (3187 bp)
Official symbol JUN [Human]
Official name jun proto-oncogene
Species Human (Homo sapiens)
Entrez Gene ID 3725
Transcript(s) for this gene NM_002228 (3338 bp), ENST00000371222
Official symbol Jun [Rat]
Official name jun proto-oncogene
Species Rat (Rattus norvegicus)
Entrez Gene ID 24516
Transcript(s) for this gene NM_021835 (3107 bp)
Official symbol Ahr [Mouse]
Official name aryl-hydrocarbon receptor
Species Mouse (Mus musculus)
Entrez Gene ID 11622
Transcript(s) for this gene NM_013464 (5494 bp), ENSMUST00000173414, NM_001314027 (5390 bp)
Official symbol AHR [Human]
Official name aryl hydrocarbon receptor
Species Human (Homo sapiens)
Entrez Gene ID 196
Transcript(s) for this gene NM_001621 (6247 bp), ENST00000492120, ENST00000242057
Official symbol Ahr [Rat]
Official name aryl hydrocarbon receptor
Species Rat (Rattus norvegicus)
Entrez Gene ID 25690
Transcript(s) for this gene NM_013149 (2574 bp)
Official symbol CDKN1A [Human]
Official name cyclin-dependent kinase inhibitor 1A (p21, Cip1)
Species Human (Homo sapiens)
Entrez Gene ID 1026
Transcript(s) for this gene NM_000389 (2175 bp), NM_001220777 (2119 bp), NM_001220778 (2284 bp), NM_078467 (2122 bp), NR_037150 (2327 bp), NR_037151 (2285 bp), NR_037152 (2120 bp), ENST00000478800, NM_001291549 (2325 bp), ENST00000244741, ENST00000373711, ENST00000405375, ENST00000448526, ENST00000615513
Official symbol SP3 [Human]
Official name Sp3 transcription factor
Species Human (Homo sapiens)
Entrez Gene ID 6670
Transcript(s) for this gene NM_001017371 (6008 bp), NM_001172712 (6350 bp), NM_003111 (6359 bp), ENST00000490182, ENST00000310015, ENST00000418194
Official symbol Sp3 [Mouse]
Official name trans-acting transcription factor 3
Species Mouse (Mus musculus)
Entrez Gene ID 20687
Transcript(s) for this gene NM_001018042 (4191 bp), NM_001098425 (4100 bp), NM_011450 (3064 bp), ENSMUST00000141372
Official symbol Sp3 [Rat]
Official name Sp3 transcription factor
Species Rat (Rattus norvegicus)
Entrez Gene ID 367846
Transcript(s) for this gene NM_001029905 (2661 bp), XM_002726189 (3972 bp), XM_002729171 (2363 bp), XM_003749489 (3954 bp), XM_008761975 (4257 bp), XM_008775440 (4264 bp)
Official symbol Kdr [Rat]
Official name kinase insert domain receptor
Species Rat (Rattus norvegicus)
Entrez Gene ID 25589
Transcript(s) for this gene NM_013062 (5892 bp)

Customers who bought these products also bought