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Cignal Reporter Assay Kits

For rapid, sensitive, and quantitative assessment of signal transduction pathway activation

  • Rapid analysis of signal transduction pathway regulation
  • Exceptional sensitivity and specificity
  • Transfection-ready constructs
  • Includes positive and negative controls
  • Real-time live cell quantification (GFP format)

Cignal Reporter Assays provided in the Cignal Reporter Assay Kit enable rapid, sensitive, and quantitative assessment of signal transduction pathway activation by measuring the activities of downstream transcription factors. Two reporter systems are available: dual-luciferase format and GFP format.

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Cignal Reporter Assay Kits are intended for molecular biology applications. These products are not intended for the diagnosis, prevention, or treatment of a disease.


0
TNFα activates NFkB signaling activity in a dose-dependent manner.
293 H cells were transfected with Cignal NFkB Reporter Assay, negative or positive control. After 24 hours, cells were treated with different doses of hTNFα for a further 24 hours. Dual-luciferase assays were performed, and reporter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and standard deviation is shown.
1
Assessing RNA interference phenotypes.

Cignal p53 Reporter Assays showed that p53 siRNA treatment abolished p53 transcription activity. HCT 116 cells were transfected with p53 reporter, negative control, and positive control, together with p53 siRNA or negative control siRNA. Dual-luciferase assays were performed. Reporter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and the standard deviation is shown.

2
Assessing overexpression phenotypes.

Cignal RBP-Jκ Reporter Assay showed upregulation of Notch signaling activity after overexpression of activated Notch1. 293 H cells were transfected with RBP-Jκ reporter, negative control, and positive control. After 24 hours, cells were infected with 100 MOI of recombinant adenoviruses expressing activated Notch1 (Ad-NICD) or 100 MOI of recombinant adenovirus expressing GFP (Ad-GFP) for another 18 hours. Dual-luciferase assays were performed. Reporter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and the standard deviation is shown.

3
Verification of small molecule drug candidate.

Cignal Retinoic Acid Response Element (RARE) Reporter Assay reported elevated retinoic acid receptor pathway activity after the treatment of all trans-retinoic acid (ATRA). CHO-K1 cells were transfected with RARE reporter, negative control, and positive control. After 16 hours, medium was changed to assay medium. After 24 hours, cells were treated with 1 µM all trans-rectinoic acid (ATRA) for 6 hours. Dual-luciferase assay was performed, and promoter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and the standard deviation is shown.

4
Cignal Reporter Assay shows that hTNFa activated NFkB signaling pathway.
293 H cells were transfected with the Cignal NFkB-GFP Reporter Assay or negative control. After 16 hours, medium was changed to assay medium. After 24 hours, cells were treated with 10 ng/ml TNFα. After 18 hours, medium was removed from the wells and fluorescence activity was measured using a fluorometer. The fluorescence activity present in treated and nontreated negative control wells was subtracted from the fluorescence activity in treated and nontreated Cignal NFkB-GFP Reporter Assay wells and relative fluorescence activities expressed as arbitrary units. Experiments were performed in triplicate and the standard deviations are shown.
5
Cignal Reporter Assay measures activation of serum response factor (SRF) transcription activity.

293 H cells were transfected with the Cignal SRF-GFP Reporter Assay or negative control. After 16 hours, medium was changed to assay medium. After 24 hours, cells were treated with 10 ng/ml PMA and 10% serum. After 18 hours, medium was removed from the wells and fluorescence activity was measured using a fluorometer. The fluorescence activity present in treated and nontreated negative control wells was subtracted from the fluorescence activity in treated and nontreated Cignal SRF-GFP Reporter Assay wells and relative fluorescence activities expressed as arbitrary units. Experiments were performed in triplicate and the standard deviations are shown.

6
Cignal Reporter Assay procedure.
7
Cignal Reporter Assay principle.
Performance
Principle

Cignal Reporter Assays consist of multiple repeats of a specific transcription factor’s binding site and basic promoter elements to drive the expression of a reporter gene (firefly luciferase or GFP). These reporters are powerful tools in functional genomics and drug discovery for assessing pathway activity. When the pathway is activated or inhibited by a drug candidate, gene knockdown, overexpression, or peptide, luciferase or GFP reporter activity is modulated and can be measured quantitatively and rapidly (see figure "Cignal Reporter Assay principle"). The Cignal Reporter Assays are available as transfection-ready constructs utilizing two reporter systems: the dual-luciferase reporter or the GFP reporter (see flowchart "Cignal Reporter Assay procedure").

The dual-luciferase format is an end-point assay providing unsurpassed sensitivity, specificity, and signal-to-noise ratios. This format is available for all Cignal Reporter Assays. Each assay includes a pathway-focused transcription factor reporter and a noninducible negative control, as well as luciferase and GFP positive controls.

The GFP format is an outstanding method for monitoring live cell pathway regulation, with single cell resolution. It includes a pathway-focused transcription factor reporter and positive and negative controls.

Procedure

Cignal Reporter Assays include a preformulated, transfection-ready pathway reporter (dual-luciferase or GFP), plus a positive and negative control. The inducible pathway reporter and noninducible negative control are transfected and subjected to experimental treatments in parallel.

Dual-luciferase

Dual-luciferase results are calculated for each transfectant. The change in the activity of each signaling pathway is determined by comparing the normalized luciferase activities of the reporter in treated versus untreated transfectants. The identically treated negative control transfectants serve as a specificity control. The positive control serves as a control for transfection efficiency, by monitoring firefly luciferase and Renilla expression.

GFP

GFP expression is quantified using a flow cytometer, fluorescence microscope, or fluorometer. The change in the activity of each signaling pathway is determined by comparing the GFP activities in treated versus untreated transfectants. The identically treated negative control transfectants serve as a specificity control. The positive control serves as a control for transfection efficiency, by monitoring GFP expression from the constitutively expressing CMV-GFP reporter.

Applications

Cignal Reporter Assays are powerful tools in functional genomics, proteomics, and drug discovery for assessing the biological impact of pathway inhibition or activation with siRNAs, proteins, and small molecule compounds.

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Brochures & Guides (1)
For cell-based analysis of pathway signaling activity
Show details
Kit Handbooks (1)
Transfection Protocols (2)
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Transfection protocols for specific cell types and plate formats that save you the time and effort of adapting existing protocols to fit your requirements. Simply select the cell type, nucleic acid, and culture format to receive a QIAGEN transfection protocol to print out or download in convenient PDF format.
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AP1 Reporter Assay Kit Cignal Reporter Assay Kits
Introduction
The Cignal AP1 Reporter Assay Kit is designed to monitor the activity of AP1-regulated signal transduction pathways in cultured cells. The activator protein-1 (AP1) transcription factor is a hetero- or homo-dimeric complex that comprises members of the proto-oncogene Jun protein family (c-Jun, JunB and JunD) and Fos protein family (c-Fos, Fos B, Fra-1 and Fra-2). The stress-activated protein kinase/Jun N-terminal kinase (SAPK/JNK) signal transduction pathway is responsible for the phosphorylation and activation of Jun, which in turn activates AP1. The AP1 reporter is designed for measuring the modulation of the JNK/AP1 pathway. The AP1 reporter is a mixture of an inducible AP1-responsive luciferase construct and a constitutively expressing Renilla construct (40:1). The AP1-responsive luciferase construct encodes the firefly luciferase reporter gene under the control of a minimal (m)CMV promoter and tandem repeats of the TPA-response element. We have experimentally optimized the number of response elements as well as the intervening sequence between response elements to maximize the signal to noise ratio. The constitutively expressing Renilla construct encodes the Renilla luciferase reporter gene under the control of a CMV immediately early enhancer/promoter and acts as an internal control for normalizing transfection efficiencies and monitoring cell viability. Using a simple dual-luciferase assay, you can easily monitor the activity of AP1-mediated signaling pathways and determine the effect of various treatments, such as gene knockdown, over-expression, and chemical compounds on those pathways
CCS-011L

The Cignal AP-1 Reporter Assay shows activation of MAPK signaling. 293-H cells were transfected with the Cignal AP-1 Reporter, negative control, and positive control (for the transfection protocol, refer to the Cignal Reporter Assay Handbook). After 24 hours of transfection, medium was changed to assay medium (Opti-MEM + 0.5% FBS + 0.1 mM NEAA + 1 mM sodium pyruvate + 100 U/ml penicillin + 100 µg/ml streptomycin) and cells were treated with 10 ng/ml PMA or an equal volume of DMSO for 18 hours. A dual-luciferase assay was performed 42 hours after transfection, and promoter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate, and the standard deviation is indicated. The Cignal AP-1 Reporter Assay measured a 43-fold increase in AP-1 transcription activity and, in turn, in corresponding MAPK signaling by 10 ng/ml PMA.
Related Biologies
MAP Kinase Signaling
Name Cignal AP1 Reporter Assay Kit (LUC) (CCS-011L)
Official symbol Mapk1 [Mouse]
Official name mitogen-activated protein kinase 1
Species Mouse (Mus musculus)
Entrez Gene ID 26413
Transcript(s) for this gene NM_001038663 (1932 bp), NM_011949 (5099 bp), ENSMUST00000145409, XM_006522147 (2926 bp)
Official symbol MAPK1 [Human]
Official name mitogen-activated protein kinase 1
Species Human (Homo sapiens)
Entrez Gene ID 5594
Transcript(s) for this gene NM_002745 (5916 bp), NM_138957 (1514 bp), ENST00000491588, ENST00000215832, ENST00000398822, ENST00000544786
Official symbol Cdk4 [Rat]
Official name cyclin-dependent kinase 4
Species Rat (Rattus norvegicus)
Entrez Gene ID 94201
Transcript(s) for this gene NM_053593 (1395 bp)
Official symbol PRDX6 [Human]
Official name peroxiredoxin 6
Species Human (Homo sapiens)
Entrez Gene ID 9588
Transcript(s) for this gene NM_004905 (1715 bp), ENST00000470017, ENST00000340385
Official symbol MAPK3 [Human]
Official name mitogen-activated protein kinase 3
Species Human (Homo sapiens)
Entrez Gene ID 5595
Transcript(s) for this gene NM_001040056 (1174 bp), NM_001109891 (1770 bp), NM_002746 (1902 bp), ENST00000494643, XR_243293 (1927 bp), ENST00000263025, ENST00000322266, ENST00000395199, ENST00000395200, ENST00000395202, ENST00000484663
Official symbol Mapk3 [Mouse]
Official name mitogen-activated protein kinase 3
Species Mouse (Mus musculus)
Entrez Gene ID 26417
Transcript(s) for this gene NM_011952 (1772 bp), ENSMUST00000145965
Official symbol TGFB1 [Human]
Official name transforming growth factor, beta 1
Species Human (Homo sapiens)
Entrez Gene ID 7040
Transcript(s) for this gene NM_000660 (2583 bp), ENST00000600196, ENST00000221930
Official symbol Tgfb1 [Mouse]
Official name transforming growth factor, beta 1
Species Mouse (Mus musculus)
Entrez Gene ID 21803
Transcript(s) for this gene NM_011577 (2191 bp), ENSMUST00000171757
Official symbol Tgfb1 [Rat]
Official name transforming growth factor, beta 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 59086
Transcript(s) for this gene NM_021578 (1482 bp)
Official symbol CXCL8 [Human]
Official name chemokine (C-X-C motif) ligand 8
Species Human (Homo sapiens)
Entrez Gene ID 3576
Transcript(s) for this gene NM_000584 (1718 bp), ENST00000483500, ENST00000307407, ENST00000401931
Official symbol CDK2 [Human]
Official name cyclin-dependent kinase 2
Species Human (Homo sapiens)
Entrez Gene ID 1017
Transcript(s) for this gene NM_001798 (2301 bp), NM_052827 (2199 bp), ENST00000556656, NM_001290230 (2121 bp), ENST00000266970, ENST00000354056, ENST00000440311, ENST00000553376
Official symbol Cdk2 [Mouse]
Official name cyclin-dependent kinase 2
Species Mouse (Mus musculus)
Entrez Gene ID 12566
Transcript(s) for this gene NM_016756 (2288 bp), NM_183417 (2432 bp), XM_006513162 (2221 bp), XM_011243321 (2187 bp)
Official symbol Cdk2 [Rat]
Official name cyclin dependent kinase 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 362817
Transcript(s) for this gene NM_199501 (2250 bp), XM_006240778 (2414 bp)
Official symbol CCNB1 [Human]
Official name cyclin B1
Species Human (Homo sapiens)
Entrez Gene ID 891
Transcript(s) for this gene NM_031966 (2177 bp), ENST00000513102, ENST00000256442
Official symbol Ccnb1 [Mouse]
Official name cyclin B1
Species Mouse (Mus musculus)
Entrez Gene ID 268697
Transcript(s) for this gene NM_172301 (2316 bp), ENSMUST00000147790, XM_011244665 (2197 bp)
Official symbol Ccnb1 [Rat]
Official name cyclin B1
Species Rat (Rattus norvegicus)
Entrez Gene ID 25203
Transcript(s) for this gene NM_171991 (3273 bp)
Official symbol MAPK10 [Human]
Official name mitogen-activated protein kinase 10
Species Human (Homo sapiens)
Entrez Gene ID 5602
Transcript(s) for this gene NM_002753 (3727 bp), NM_138980 (4213 bp), NM_138981 (3511 bp), NM_138982 (4186 bp), ENST00000515650, XM_005263129 (6612 bp), XM_005263130 (6503 bp), XM_005263131 (6904 bp), XM_005263135 (6909 bp), XM_005263136 (6029 bp), XM_005263138 (5647 bp), XM_006714267 (6599 bp), XM_006714268 (6777 bp), XM_006714269 (6909 bp), XM_006714270 (6386 bp), XM_006714271 (5111 bp), XM_006714272 (4769 bp), ENST00000359221, ENST00000361569, ENST00000395157, ENST00000395160, ENST00000395161, ENST00000395166, ENST00000395169, ENST00000449047
Official symbol Mapk10 [Mouse]
Official name mitogen-activated protein kinase 10
Species Mouse (Mus musculus)
Entrez Gene ID 26414
Transcript(s) for this gene NM_001081567 (6599 bp), NM_009158 (6604 bp), ENSMUST00000152609, XM_006534943 (2158 bp), XM_006534944 (2163 bp), XM_006534945 (1599 bp), XM_006534946 (4893 bp), XM_006534947 (2184 bp), XM_006534948 (1859 bp), XM_006534949 (4912 bp), XM_006534950 (4906 bp), XM_006534951 (4924 bp), XM_006534952 (809 bp), NM_001310683 (6626 bp), NM_001310685 (6039 bp), NM_001310686 (6071 bp), NM_001318102 (6599 bp), NM_001318131 (6044 bp), XM_011249449 (4355 bp), XM_011249450 (4730 bp)
Official symbol Mapk10 [Rat]
Official name mitogen activated protein kinase 10
Species Rat (Rattus norvegicus)
Entrez Gene ID 25272
Transcript(s) for this gene NM_012806 (2786 bp), NM_001270556 (2759 bp), XM_008769992 (9394 bp)
Official symbol FOS [Human]
Official name FBJ murine osteosarcoma viral oncogene homolog
Species Human (Homo sapiens)
Entrez Gene ID 2353
Transcript(s) for this gene NM_005252 (2158 bp), ENST00000556324, ENST00000303562, ENST00000535987, ENST00000554617, ENST00000555242, ENST00000555347, ENST00000555686
Official symbol Fos [Mouse]
Official name FBJ osteosarcoma oncogene
Species Mouse (Mus musculus)
Entrez Gene ID 14281
Transcript(s) for this gene NM_010234 (2107 bp), ENSMUST00000140525
Official symbol Fos [Rat]
Official name FBJ osteosarcoma oncogene
Species Rat (Rattus norvegicus)
Entrez Gene ID 314322
Transcript(s) for this gene NM_022197 (1589 bp), XM_234422 (1713 bp)
Official symbol MAP3K3 [Human]
Official name mitogen-activated protein kinase kinase kinase 3
Species Human (Homo sapiens)
Entrez Gene ID 4215
Transcript(s) for this gene NM_002401 (4750 bp), NM_203351 (4843 bp), ENST00000578622, XM_005257376 (5209 bp), XM_005257377 (4443 bp), XM_005257378 (2711 bp), XM_006721909 (4381 bp), ENST00000361357, ENST00000361733, ENST00000577395, ENST00000579585, ENST00000584573
Official symbol Map3k3 [Mouse]
Official name mitogen-activated protein kinase kinase kinase 3
Species Mouse (Mus musculus)
Entrez Gene ID 26406
Transcript(s) for this gene NM_011947 (3161 bp), ENSMUST00000129793, XM_011249037 (4874 bp)
Official symbol Map3k3 [Rat]
Official name mitogen activated protein kinase kinase kinase 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 303604
Transcript(s) for this gene NM_001107058 (4640 bp), XM_001081582 (4731 bp), XM_221034 (4731 bp), XM_008768358 (4631 bp)
Official symbol HRAS [Human]
Official name Harvey rat sarcoma viral oncogene homolog
Species Human (Homo sapiens)
Entrez Gene ID 3265
Transcript(s) for this gene NM_001130442 (1169 bp), NM_005343 (1061 bp), NM_176795 (1251 bp), ENST00000482021, XM_006718217 (1120 bp), XM_006725136 (1120 bp), XR_242795 (1137 bp), ENST00000311189, ENST00000397594, ENST00000397596, ENST00000417302, ENST00000451590
Official symbol Hras [Mouse]
Official name Harvey rat sarcoma virus oncogene
Species Mouse (Mus musculus)
Entrez Gene ID 15461
Transcript(s) for this gene NM_001130443 (2190 bp), NM_001130444 (2272 bp), NM_008284 (2043 bp), ENSMUST00000134008, XM_006536157 (1301 bp), XM_006536158 (1154 bp), XM_006536159 (1068 bp), XM_006536160 (1383 bp), XR_389950 (0 bp), XR_389951 (0 bp), XR_389952 (0 bp)
Official symbol Hras [Rat]
Official name Harvey rat sarcoma virus oncogene
Species Rat (Rattus norvegicus)
Entrez Gene ID 293621
Transcript(s) for this gene NM_001098241 (1392 bp), NM_001130441 (1246 bp), XM_001061671 (1248 bp), XM_001062236 (1704 bp), XM_215123 (1331 bp), XM_006230535 (1379 bp)
Official symbol MAPK11 [Human]
Official name mitogen-activated protein kinase 11
Species Human (Homo sapiens)
Entrez Gene ID 5600
Transcript(s) for this gene NM_002751 (2463 bp), NM_138993 (1503 bp), ENST00000495277, ENST00000330651
Official symbol Mapk11 [Mouse]
Official name mitogen-activated protein kinase 11
Species Mouse (Mus musculus)
Entrez Gene ID 19094
Transcript(s) for this gene NM_011161 (2452 bp), XM_006520626 (3422 bp), XM_006520627 (2506 bp), XM_006520628 (2340 bp), XM_006520629 (3376 bp), XM_006520630 (941 bp), XM_011245521 (2422 bp)
Official symbol Mapk11 [Rat]
Official name mitogen-activated protein kinase 11
Species Rat (Rattus norvegicus)
Entrez Gene ID 689314
Transcript(s) for this gene NM_001109532 (1379 bp), XM_001073684 (1610 bp), XM_001073721 (2401 bp), XM_008765792 (2480 bp)
Official symbol CDKN2B [Human]
Official name cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
Species Human (Homo sapiens)
Entrez Gene ID 1030
Transcript(s) for this gene NM_004936 (3878 bp), NM_078487 (4001 bp), ENST00000579591, ENST00000276925, ENST00000380142
Official symbol Cdkn2b [Mouse]
Official name cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
Species Mouse (Mus musculus)
Entrez Gene ID 12579
Transcript(s) for this gene NM_007670 (1393 bp), XM_989888 (962 bp)
Official symbol Cdkn2b [Rat]
Official name cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
Species Rat (Rattus norvegicus)
Entrez Gene ID 25164
Transcript(s) for this gene NM_130812 (2323 bp), XM_006238380 (1733 bp), XM_006238381 (1364 bp)
Official symbol SMAD4 [Human]
Official name SMAD family member 4
Species Human (Homo sapiens)
Entrez Gene ID 4089
Transcript(s) for this gene NM_005359 (8789 bp), ENST00000592911, ENST00000342988, ENST00000398417, ENST00000588745
Official symbol Smad4 [Mouse]
Official name SMAD family member 4
Species Mouse (Mus musculus)
Entrez Gene ID 17128
Transcript(s) for this gene NM_008540 (3361 bp), XM_001001632 (2703 bp), XM_001001642 (2812 bp), XM_001001655 (3841 bp), XM_001001668 (3482 bp), XM_001001679 (3873 bp), XM_001001692 (3928 bp), XM_001001701 (4156 bp), XM_987755 (2706 bp), XM_987790 (2815 bp), XM_987848 (3485 bp), XM_987970 (4159 bp), ENSMUST00000147315, XM_006525701 (2890 bp), XM_006525702 (2904 bp), XM_011246855 (3141 bp)
Official symbol Smad4 [Rat]
Official name SMAD family member 4
Species Rat (Rattus norvegicus)
Entrez Gene ID 50554
Transcript(s) for this gene NM_019275 (3056 bp)
Official symbol NFATC4 [Human]
Official name nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
Species Human (Homo sapiens)
Entrez Gene ID 4776
Transcript(s) for this gene NM_001136022 (5747 bp), NM_001198965 (4652 bp), NM_001198966 (4630 bp), NM_001198967 (4664 bp), NM_004554 (4976 bp), ENST00000557028, ENST00000556957, ENST00000556302, NM_001288802 (5538 bp), XM_006720153 (1883 bp), ENST00000250373, ENST00000413692, ENST00000422617, ENST00000424781, ENST00000539237, ENST00000553469, ENST00000553708, ENST00000553879, ENST00000554050, ENST00000554344, ENST00000554473, ENST00000554591, ENST00000554661, ENST00000554966, ENST00000555167, ENST00000555393, ENST00000555453, ENST00000555590, ENST00000555802, ENST00000556169, ENST00000556279, ENST00000556759, ENST00000557451, ENST00000557767
Official symbol Nfatc4 [Mouse]
Official name nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
Species Mouse (Mus musculus)
Entrez Gene ID 73181
Transcript(s) for this gene NM_001168346 (4036 bp), NM_023699 (3284 bp)
Official symbol Nfatc4 [Rat]
Official name nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
Species Rat (Rattus norvegicus)
Entrez Gene ID 305897
Transcript(s) for this gene NM_001107264 (3170 bp), XM_001061815 (3263 bp), XM_240184 (3263 bp)
Official symbol CCNA2 [Human]
Official name cyclin A2
Species Human (Homo sapiens)
Entrez Gene ID 890
Transcript(s) for this gene NM_001237 (2811 bp), ENST00000274026, ENST00000618014
Official symbol Ccna2 [Mouse]
Official name cyclin A2
Species Mouse (Mus musculus)
Entrez Gene ID 12428
Transcript(s) for this gene NM_009828 (2827 bp), ENSMUST00000156575
Official symbol Ccna2 [Rat]
Official name cyclin A2
Species Rat (Rattus norvegicus)
Entrez Gene ID 114494
Transcript(s) for this gene NM_053702 (1730 bp), XM_342229 (1734 bp), XM_006232266 (1754 bp), XM_008760903 (1749 bp)
Official symbol IL2 [Human]
Official name interleukin 2
Species Human (Homo sapiens)
Entrez Gene ID 3558
Transcript(s) for this gene NM_000586 (822 bp), ENST00000477645, ENST00000226730
Official symbol Il2 [Mouse]
Official name interleukin 2
Species Mouse (Mus musculus)
Entrez Gene ID 16183
Transcript(s) for this gene NM_008366 (955 bp)
Official symbol Il2 [Rat]
Official name interleukin 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 116562
Transcript(s) for this gene NM_053836 (740 bp)
Official symbol MAP4K1 [Human]
Official name mitogen-activated protein kinase kinase kinase kinase 1
Species Human (Homo sapiens)
Entrez Gene ID 11184
Transcript(s) for this gene NM_001042600 (2721 bp), NM_007181 (2819 bp), ENST00000593196, XM_006722993 (2457 bp), ENST00000396857, ENST00000586296, ENST00000589130, ENST00000591517
Official symbol Map4k1 [Mouse]
Official name mitogen-activated protein kinase kinase kinase kinase 1
Species Mouse (Mus musculus)
Entrez Gene ID 26411
Transcript(s) for this gene NM_008279 (2699 bp), XM_006539995 (3423 bp), XM_006539996 (3380 bp), XM_006539997 (3413 bp), XM_006539998 (3325 bp), XM_006539999 (2723 bp), XM_006540000 (3254 bp)
Official symbol Map4k1 [Rat]
Official name mitogen activated protein kinase kinase kinase kinase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 292763
Transcript(s) for this gene NM_001106243 (2699 bp), XM_001074916 (2817 bp), XM_214883 (2693 bp), XM_006228716 (3661 bp), XM_008759122 (3526 bp)
Official symbol CDK4 [Human]
Official name cyclin-dependent kinase 4
Species Human (Homo sapiens)
Entrez Gene ID 1019
Transcript(s) for this gene NM_000075 (2020 bp), ENST00000552713, ENST00000257904, ENST00000312990, ENST00000549606
Official symbol Cdk4 [Mouse]
Official name cyclin-dependent kinase 4
Species Mouse (Mus musculus)
Entrez Gene ID 12567
Transcript(s) for this gene NM_009870 (1365 bp), ENSMUST00000145670, XM_006513163 (1184 bp)
Official symbol E2F1 [Human]
Official name E2F transcription factor 1
Species Human (Homo sapiens)
Entrez Gene ID 1869
Transcript(s) for this gene NM_005225 (2722 bp), ENST00000343380
Official symbol E2f1 [Mouse]
Official name E2F transcription factor 1
Species Mouse (Mus musculus)
Entrez Gene ID 13555
Transcript(s) for this gene NM_007891 (2739 bp), NM_001291105 (2695 bp), XM_006498694 (2502 bp)
Official symbol E2f1 [Rat]
Official name E2F transcription factor 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 399489
Transcript(s) for this gene NM_001100778 (2643 bp), XM_001065036 (2778 bp), XM_230765 (2643 bp), XM_008762363 (2640 bp)
Official symbol CDKN1C [Human]
Official name cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Species Human (Homo sapiens)
Entrez Gene ID 1028
Transcript(s) for this gene NM_000076 (1943 bp), NM_001122630 (1776 bp), NM_001122631 (1771 bp), ENST00000471157, XM_005252731 (1787 bp), XM_005252732 (1293 bp), XM_006725125 (1787 bp), XM_006725126 (1293 bp), ENST00000380725, ENST00000414822, ENST00000430149, ENST00000440480
Official symbol Cdkn1b [Mouse]
Official name cyclin-dependent kinase inhibitor 1B
Species Mouse (Mus musculus)
Entrez Gene ID 12576
Transcript(s) for this gene NM_009875 (2405 bp), XM_006505466 (4611 bp)
Official symbol Cdkn1a [Mouse]
Official name cyclin-dependent kinase inhibitor 1A (P21)
Species Mouse (Mus musculus)
Entrez Gene ID 12575
Transcript(s) for this gene NM_001111099 (1943 bp), NM_007669 (1913 bp)
Official symbol Cdkn1c [Mouse]
Official name cyclin-dependent kinase inhibitor 1C (P57)
Species Mouse (Mus musculus)
Entrez Gene ID 12577
Transcript(s) for this gene NM_001161624 (1952 bp), NM_009876 (1914 bp), XM_006508467 (2093 bp), XM_006508468 (2094 bp), XM_006508469 (2053 bp), XM_006508470 (2051 bp), XM_006508471 (1939 bp)
Official symbol Cdkn1b [Rat]
Official name cyclin-dependent kinase inhibitor 1B
Species Rat (Rattus norvegicus)
Entrez Gene ID 83571
Transcript(s) for this gene NM_031762 (1755 bp), XM_006237539 (2403 bp)
Official symbol MAP2K5 [Human]
Official name mitogen-activated protein kinase kinase 5
Species Human (Homo sapiens)
Entrez Gene ID 5607
Transcript(s) for this gene NM_001206804 (1801 bp), NM_002757 (2355 bp), NM_145160 (2385 bp), NM_145161 (2229 bp), NM_145162 (1509 bp), ENST00000560591, ENST00000178640, ENST00000340972, ENST00000354498, ENST00000395476
Official symbol Map2k5 [Mouse]
Official name mitogen-activated protein kinase kinase 5
Species Mouse (Mus musculus)
Entrez Gene ID 23938
Transcript(s) for this gene NM_011840 (2258 bp), XM_981477 (1178 bp), XM_981529 (1457 bp), XM_981569 (2289 bp), XM_981608 (2286 bp), XM_981645 (2316 bp), XM_006511142 (2890 bp), XM_006511143 (2863 bp), XM_006511144 (2860 bp), XM_006511145 (2819 bp), XM_006511146 (2816 bp), XM_006511147 (1513 bp), XM_006511148 (1529 bp), XM_011242740 (3357 bp), XM_011242741 (1485 bp)
Official symbol Map2k5 [Rat]
Official name mitogen activated protein kinase kinase 5
Species Rat (Rattus norvegicus)
Entrez Gene ID 29568
Transcript(s) for this gene NM_001033987 (2357 bp), NM_017246 (2327 bp), XM_006243229 (2311 bp), XM_008766221 (1477 bp)
Official symbol CDK6 [Human]
Official name cyclin-dependent kinase 6
Species Human (Homo sapiens)
Entrez Gene ID 1021
Transcript(s) for this gene NM_001145306 (11733 bp), NM_001259 (11628 bp), ENST00000491250, XM_006715835 (11837 bp), XM_006715836 (1381 bp), ENST00000265734, ENST00000424848
Official symbol Cdk6 [Mouse]
Official name cyclin-dependent kinase 6
Species Mouse (Mus musculus)
Entrez Gene ID 12571
Transcript(s) for this gene NM_009873 (11534 bp), XM_006503543 (11527 bp)
Official symbol MAP3K2 [Human]
Official name mitogen-activated protein kinase kinase kinase 2
Species Human (Homo sapiens)
Entrez Gene ID 10746
Transcript(s) for this gene NM_006609 (10870 bp), XM_001128799 (9219 bp), ENST00000344908, ENST00000409947
Official symbol Map3k2 [Mouse]
Official name mitogen-activated protein kinase kinase kinase 2
Species Mouse (Mus musculus)
Entrez Gene ID 26405
Transcript(s) for this gene NM_011946 (10791 bp)
Official symbol Map3k2 [Rat]
Official name mitogen activated protein kinase kinase kinase 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 171492
Transcript(s) for this gene NM_138503 (2524 bp), XM_001059840 (2524 bp), XM_001067270 (2524 bp), XM_226073 (2073 bp)
Official symbol MAPK7 [Human]
Official name mitogen-activated protein kinase 7
Species Human (Homo sapiens)
Entrez Gene ID 5598
Transcript(s) for this gene NM_002749 (2972 bp), NM_139032 (2780 bp), NM_139033 (3183 bp), NM_139034 (2884 bp), ENST00000573466, ENST00000570306, ENST00000486905, XM_005256719 (2622 bp), XM_006721557 (2910 bp), XM_006721558 (3168 bp), XM_006721559 (3077 bp), XM_006721560 (2910 bp), ENST00000299612, ENST00000308406, ENST00000395602, ENST00000395604
Official symbol Mapk7 [Mouse]
Official name mitogen-activated protein kinase 7
Species Mouse (Mus musculus)
Entrez Gene ID 23939
Transcript(s) for this gene NM_011841 (2999 bp), ENSMUST00000152755, NM_001291033 (3049 bp), NM_001291034 (3124 bp), NM_001291035 (3265 bp), NM_001291036 (3114 bp), NM_001291037 (3264 bp), XM_006533277 (2968 bp), XM_006533278 (2559 bp), XM_006533280 (3111 bp), XM_006533281 (3129 bp), XM_006533282 (3234 bp), XM_006533284 (3165 bp), XM_006533285 (3092 bp), XM_006533286 (3167 bp), XM_011249008 (3352 bp)
Official symbol Mapk7 [Rat]
Official name mitogen-activated protein kinase 7
Species Rat (Rattus norvegicus)
Entrez Gene ID 114509
Transcript(s) for this gene NM_001191547 (2738 bp), XM_002724501 (2738 bp), XM_002727717 (2738 bp), XM_340813 (2955 bp), XM_006246417 (3057 bp), XM_006246418 (3520 bp), XM_006246420 (2593 bp), XM_006246421 (2565 bp), XM_008767756 (2615 bp)
Official symbol Kcnn1 [Mouse]
Official name potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
Species Mouse (Mus musculus)
Entrez Gene ID 84036
Transcript(s) for this gene NM_032397 (4042 bp), XM_006509804 (3003 bp), XM_006509805 (2994 bp), XM_006509806 (2892 bp), XM_006509807 (3271 bp), XM_006509808 (3442 bp), XM_006509809 (1691 bp), XM_006509810 (1585 bp), XM_006509811 (1565 bp)
Official symbol Cdc42 [Mouse]
Official name cell division cycle 42
Species Mouse (Mus musculus)
Entrez Gene ID 12540
Transcript(s) for this gene NM_001243769 (1521 bp), NM_009861 (2151 bp), XR_104893 (2151 bp), XM_011250182 (2134 bp)
Official symbol CDC42 [Human]
Official name cell division cycle 42
Species Human (Homo sapiens)
Entrez Gene ID 998
Transcript(s) for this gene NM_001039802 (2308 bp), NM_001791 (2182 bp), NM_044472 (1530 bp), ENST00000498236, ENST00000315554, ENST00000344548, ENST00000400259
Official symbol Cdc42 [Rat]
Official name cell division cycle 42
Species Rat (Rattus norvegicus)
Entrez Gene ID 64465
Transcript(s) for this gene NM_171994 (955 bp), XM_008764286 (2555 bp), XM_008764287 (1498 bp)
Official symbol Myc [Mouse]
Official name myelocytomatosis oncogene
Species Mouse (Mus musculus)
Entrez Gene ID 17869
Transcript(s) for this gene NM_001177352 (2399 bp), NM_001177353 (2396 bp), NM_001177354 (2396 bp), NM_010849 (2399 bp)
Official symbol MYC [Human]
Official name v-myc avian myelocytomatosis viral oncogene homolog
Species Human (Homo sapiens)
Entrez Gene ID 4609
Transcript(s) for this gene NM_002467 (2379 bp), XM_001129520 (567 bp), XM_001129632 (567 bp), ENST00000259523, ENST00000377970, ENST00000524013, ENST00000613283, ENST00000621592
Official symbol Myc [Rat]
Official name myelocytomatosis oncogene
Species Rat (Rattus norvegicus)
Entrez Gene ID 24577
Transcript(s) for this gene NM_012603 (2355 bp)
Official symbol Hspb1 [Mouse]
Official name heat shock protein 1
Species Mouse (Mus musculus)
Entrez Gene ID 15507
Transcript(s) for this gene NM_013560 (913 bp)
Official symbol HSPB1 [Human]
Official name heat shock 27kDa protein 1
Species Human (Homo sapiens)
Entrez Gene ID 3315
Transcript(s) for this gene NM_001540 (914 bp), ENST00000248553, ENST00000429938
Official symbol Hspb1 [Rat]
Official name heat shock protein family B (small) member 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24471
Transcript(s) for this gene NM_031970 (890 bp)
Official symbol Chuk [Mouse]
Official name conserved helix-loop-helix ubiquitous kinase
Species Mouse (Mus musculus)
Entrez Gene ID 12675
Transcript(s) for this gene NM_001162410 (3483 bp), NM_007700 (3500 bp), ENSMUST00000149091, XM_006526623 (1561 bp), XM_011247129 (2394 bp)
Official symbol CHUK [Human]
Official name conserved helix-loop-helix ubiquitous kinase
Species Human (Homo sapiens)
Entrez Gene ID 1147
Transcript(s) for this gene NM_001278 (3539 bp), ENST00000590930, XR_246062 (3783 bp), ENST00000370397
Official symbol Chuk [Rat]
Official name conserved helix-loop-helix ubiquitous kinase
Species Rat (Rattus norvegicus)
Entrez Gene ID 309361
Transcript(s) for this gene NM_001107588 (3526 bp), XM_001061709 (3525 bp), XM_219857 (3525 bp), XM_006231481 (3507 bp), XM_008760418 (3487 bp), XM_008760419 (2494 bp)
Official symbol Trp53 [Mouse]
Official name transformation related protein 53
Species Mouse (Mus musculus)
Entrez Gene ID 22059
Transcript(s) for this gene NM_001127233 (1877 bp), NM_011640 (1781 bp), ENSMUST00000147512, XM_006533157 (2157 bp), XM_006533158 (1843 bp)
Official symbol TP53 [Human]
Official name tumor protein p53
Species Human (Homo sapiens)
Entrez Gene ID 7157
Transcript(s) for this gene NM_000546 (2591 bp), NM_001126112 (2588 bp), NM_001126113 (2651 bp), NM_001126114 (2724 bp), NM_001126115 (2271 bp), NM_001126116 (2404 bp), NM_001126117 (2331 bp), NM_001126118 (2708 bp), NM_001276695 (2651 bp), NM_001276696 (2724 bp), NM_001276697 (2271 bp), NM_001276698 (2404 bp), NM_001276699 (2331 bp), NM_001276760 (2591 bp), NM_001276761 (2588 bp), ENST00000574684, ENST00000269305, ENST00000359597, ENST00000413465, ENST00000420246, ENST00000445888, ENST00000455263, ENST00000504290, ENST00000504937, ENST00000510385, ENST00000610292, ENST00000610538, ENST00000610623, ENST00000615910, ENST00000617185, ENST00000618944, ENST00000619186, ENST00000619485, ENST00000620739, ENST00000622645
Official symbol Tp53 [Rat]
Official name tumor protein p53
Species Rat (Rattus norvegicus)
Entrez Gene ID 24842
Transcript(s) for this gene NM_030989 (1792 bp), XM_006246594 (2185 bp), XM_006246595 (2542 bp), XM_008767773 (1321 bp)
Official symbol Grb2 [Mouse]
Official name growth factor receptor bound protein 2
Species Mouse (Mus musculus)
Entrez Gene ID 14784
Transcript(s) for this gene NM_008163 (2725 bp), NM_001313936 (2550 bp), NM_001313937 (2699 bp)
Official symbol GRB2 [Human]
Official name growth factor receptor-bound protein 2
Species Human (Homo sapiens)
Entrez Gene ID 2885
Transcript(s) for this gene NM_002086 (3303 bp), NM_203506 (3181 bp), ENST00000583912, ENST00000316615, ENST00000316804, ENST00000392562, ENST00000392563, ENST00000392564, ENST00000578961
Official symbol Grb2 [Rat]
Official name growth factor receptor bound protein 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 81504
Transcript(s) for this gene NM_030846 (2608 bp)
Official symbol Mapk3 [Rat]
Official name mitogen activated protein kinase 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 50689
Transcript(s) for this gene NM_017347 (1875 bp), XM_001079997 (1653 bp)
Official symbol Map3k1 [Mouse]
Official name mitogen-activated protein kinase kinase kinase 1
Species Mouse (Mus musculus)
Entrez Gene ID 26401
Transcript(s) for this gene NM_011945 (6963 bp), ENSMUST00000175936, XM_006517664 (6477 bp), XM_006517665 (6455 bp), XM_006517666 (9638 bp), XM_006517667 (6922 bp), XM_011244663 (6942 bp), XM_011244664 (9832 bp)
Official symbol MAP3K1 [Human]
Official name mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
Species Human (Homo sapiens)
Entrez Gene ID 4214
Transcript(s) for this gene NM_005921 (7522 bp), XM_001128827 (7793 bp), XM_042066 (7719 bp), ENST00000469188, XM_005248519 (6790 bp), XM_005248520 (6585 bp), ENST00000399503
Official symbol Map3k1 [Rat]
Official name mitogen activated protein kinase kinase kinase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 116667
Transcript(s) for this gene NM_053887 (5180 bp), XM_001074670 (5154 bp)
Official symbol Ccne1 [Mouse]
Official name cyclin E1
Species Mouse (Mus musculus)
Entrez Gene ID 12447
Transcript(s) for this gene NM_007633 (2022 bp), ENSMUST00000137097, ENSMUST00000128785
Official symbol CCNE1 [Human]
Official name cyclin E1
Species Human (Homo sapiens)
Entrez Gene ID 898
Transcript(s) for this gene NM_001238 (2021 bp), NM_057182 (1787 bp), ENST00000586912, XM_005259370 (1917 bp), XM_006723457 (1793 bp), ENST00000262643, ENST00000357943, ENST00000444983
Official symbol Ccne1 [Rat]
Official name cyclin E1
Species Rat (Rattus norvegicus)
Entrez Gene ID 25729
Transcript(s) for this gene NM_001100821 (1945 bp), XM_001077331 (1814 bp), XM_574426 (1814 bp), XM_006228904 (2081 bp)
Official symbol Mef2c [Mouse]
Official name myocyte enhancer factor 2C
Species Mouse (Mus musculus)
Entrez Gene ID 17260
Transcript(s) for this gene NM_001170537 (6427 bp), NM_025282 (6325 bp), XM_006517120 (6574 bp), XM_006517121 (6571 bp), XM_006517122 (6445 bp), XM_006517123 (6448 bp), XM_006517124 (6483 bp), XM_006517125 (6021 bp), XM_006517126 (6576 bp), XM_006517127 (6550 bp), XM_006517128 (6552 bp), XM_006517129 (6476 bp), XM_006517130 (6452 bp), XM_006517131 (6449 bp), XM_006517132 (6452 bp), XM_006517133 (6611 bp)
Official symbol MEF2C [Human]
Official name myocyte enhancer factor 2C
Species Human (Homo sapiens)
Entrez Gene ID 4208
Transcript(s) for this gene NM_001131005 (6194 bp), NM_001193347 (6254 bp), NM_001193348 (5766 bp), NM_001193349 (5694 bp), NM_001193350 (6446 bp), NM_002397 (6449 bp), ENST00000515715, XM_005248511 (5973 bp), XM_006714618 (6188 bp), XM_006714619 (6295 bp), XM_006714620 (6178 bp), XM_006714621 (6160 bp), XM_006714622 (6154 bp), XM_006714623 (6088 bp), XM_006714624 (6064 bp), XM_006714625 (6214 bp), ENST00000340208, ENST00000424173, ENST00000437473, ENST00000504921, ENST00000506554, ENST00000508569, ENST00000510942, ENST00000514015, ENST00000514028, ENST00000625585, ENST00000625674, ENST00000626391, ENST00000627659, ENST00000628656, ENST00000629612
Official symbol Mef2c [Rat]
Official name myocyte enhancer factor 2C
Species Rat (Rattus norvegicus)
Entrez Gene ID 499497
Transcript(s) for this gene XM_001056692 (1899 bp), XM_574821 (825 bp), XM_003749164 (3517 bp), XM_006223955 (6535 bp), XM_006223957 (6228 bp), XM_006223960 (6511 bp), XM_006223962 (6439 bp), XM_006223963 (6414 bp), XM_006231731 (6448 bp), XM_006231733 (6228 bp), XM_006231736 (6424 bp), XM_006231738 (6352 bp), XM_006231739 (6328 bp), XM_008760642 (6128 bp), XM_008775027 (6128 bp)
Official symbol CDKN1B [Human]
Official name cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Species Human (Homo sapiens)
Entrez Gene ID 1027
Transcript(s) for this gene NM_004064 (2535 bp), ENST00000477087, ENST00000228872, ENST00000396340
Official symbol ELK1 [Human]
Official name ELK1, member of ETS oncogene family
Species Human (Homo sapiens)
Entrez Gene ID 2002
Transcript(s) for this gene NM_001114123 (2934 bp), NM_005229 (2828 bp), NM_001257168 (2056 bp), ENST00000480157, ENST00000247161, ENST00000343894, ENST00000376983
Official symbol Esr1 [Mouse]
Official name estrogen receptor 1 (alpha)
Species Mouse (Mus musculus)
Entrez Gene ID 13982
Transcript(s) for this gene NM_007956 (6248 bp), XM_985634 (3048 bp), XM_985672 (6199 bp), XM_985704 (6760 bp), ENSMUST00000149195, XM_006512432 (6377 bp), XM_006512433 (6250 bp), XM_006512434 (6173 bp), XM_006512435 (6123 bp), XM_006512436 (2916 bp), NM_001302531 (6218 bp), NM_001302532 (6358 bp), NM_001302533 (2730 bp), XM_011243066 (6188 bp), XM_011243067 (6189 bp), XM_011243068 (6158 bp), XM_011243069 (1346 bp)
Official symbol ESR1 [Human]
Official name estrogen receptor 1
Species Human (Homo sapiens)
Entrez Gene ID 2099
Transcript(s) for this gene NM_000125 (6330 bp), NM_001122740 (6357 bp), NM_001122741 (6314 bp), NM_001122742 (6466 bp), ENST00000488573, NM_001291230 (6320 bp), NM_001291241 (6311 bp), XM_006715374 (6282 bp), XM_006715375 (5809 bp), ENST00000206249, ENST00000338799, ENST00000406599, ENST00000427531, ENST00000440973, ENST00000443427, ENST00000456483
Official symbol Esr1 [Rat]
Official name estrogen receptor 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24890
Transcript(s) for this gene NM_012689 (2090 bp), XM_006227832 (6792 bp), XM_008758703 (6840 bp), XM_008758704 (6764 bp)
Official symbol Cdkn2c [Mouse]
Official name cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Species Mouse (Mus musculus)
Entrez Gene ID 12580
Transcript(s) for this gene NM_007671 (1134 bp), NM_001301368 (2066 bp), XM_006502698 (2059 bp)
Official symbol CDKN2C [Human]
Official name cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Species Human (Homo sapiens)
Entrez Gene ID 1031
Transcript(s) for this gene NM_001262 (2104 bp), NM_078626 (1273 bp), ENST00000262662, ENST00000371761, ENST00000396148
Official symbol Cdkn2c [Rat]
Official name cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Species Rat (Rattus norvegicus)
Entrez Gene ID 54238
Transcript(s) for this gene NM_131902 (1462 bp)
Official symbol Mapk8ip1 [Mouse]
Official name mitogen-activated protein kinase 8 interacting protein 1
Species Mouse (Mus musculus)
Entrez Gene ID 19099
Transcript(s) for this gene NM_001202445 (3246 bp), NM_001202446 (3171 bp), NM_011162 (2954 bp), ENSMUST00000149653, XM_006498953 (2443 bp), XM_006498954 (2838 bp)
Official symbol Mapk8ip1 [Rat]
Official name mitogen-activated protein kinase 8 interacting protein 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 116457
Transcript(s) for this gene NM_053777 (3003 bp)
Official symbol Ksr1 [Mouse]
Official name kinase suppressor of ras 1
Species Mouse (Mus musculus)
Entrez Gene ID 16706
Transcript(s) for this gene NM_013571 (4087 bp), XM_006532334 (5704 bp), XM_006532335 (3186 bp), XM_006532336 (2884 bp), XM_006532337 (5657 bp), XM_006532338 (5615 bp), XM_006532339 (6484 bp), XM_006532340 (5249 bp)
Official symbol KSR1 [Human]
Official name kinase suppressor of ras 1
Species Human (Homo sapiens)
Entrez Gene ID 8844
Transcript(s) for this gene NM_014238 (4552 bp), XM_290793 (3591 bp), ENST00000583998, XM_006722151 (6015 bp), XM_006722152 (5973 bp), XM_006722153 (5932 bp), XM_006722154 (5890 bp), XM_006722155 (7318 bp), XM_006722156 (2739 bp), XM_006722157 (5599 bp), XM_006722158 (5747 bp), XM_006722159 (5410 bp), ENST00000268763, ENST00000398988, ENST00000509603, ENST00000578981, ENST00000582410
Official symbol Ksr1 [Rat]
Official name kinase suppressor of ras 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 360573
Transcript(s) for this gene NM_001108284 (4166 bp), XM_001080891 (2782 bp), XM_340852 (2782 bp), XM_003750864 (2625 bp), XM_006246924 (5774 bp), XM_006246926 (5691 bp), XM_006246927 (5649 bp), XM_008768063 (5859 bp), XM_008768064 (5816 bp), XM_008768065 (5777 bp), XM_008768066 (5834 bp), XM_008768067 (2888 bp)
Official symbol Fosl1 [Mouse]
Official name fos-like antigen 1
Species Mouse (Mus musculus)
Entrez Gene ID 14283
Transcript(s) for this gene NM_010235 (1705 bp)
Official symbol FOSL1 [Human]
Official name FOS-like antigen 1
Species Human (Homo sapiens)
Entrez Gene ID 8061
Transcript(s) for this gene NM_005438 (1759 bp), NM_001300844 (1651 bp), NM_001300855 (1754 bp), NM_001300856 (1561 bp), NM_001300857 (1453 bp), XM_005274311 (1631 bp), ENST00000312562, ENST00000448083, ENST00000531493, ENST00000532401
Official symbol Fosl1 [Rat]
Official name fos-like antigen 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 25445
Transcript(s) for this gene NM_012953 (1663 bp)
Official symbol MST1 [Human]
Official name macrophage stimulating 1 (hepatocyte growth factor-like)
Species Human (Homo sapiens)
Entrez Gene ID 4485
Transcript(s) for this gene NM_020998 (2348 bp), ENST00000498021, ENST00000497359, ENST00000493836, ENST00000484144, ENST00000479115, XM_006713166 (2961 bp), XM_006713167 (2984 bp), XM_006713168 (2796 bp), XM_006713169 (2485 bp), ENST00000449682
Official symbol Mapk6 [Mouse]
Official name mitogen-activated protein kinase 6
Species Mouse (Mus musculus)
Entrez Gene ID 50772
Transcript(s) for this gene NM_015806 (4205 bp), NM_027418 (4209 bp), ENSMUST00000174034
Official symbol MAPK6 [Human]
Official name mitogen-activated protein kinase 6
Species Human (Homo sapiens)
Entrez Gene ID 5597
Transcript(s) for this gene NM_002748 (4225 bp), ENST00000560802, XM_005254536 (4159 bp), XM_005254537 (4052 bp), XM_005254538 (4101 bp), XM_005254539 (4079 bp), ENST00000261845
Official symbol Mapk6 [Rat]
Official name mitogen-activated protein kinase 6
Species Rat (Rattus norvegicus)
Entrez Gene ID 58840
Transcript(s) for this gene NM_031622 (4194 bp), XM_006243409 (4674 bp)
Official symbol Map2k7 [Mouse]
Official name mitogen-activated protein kinase kinase 7
Species Mouse (Mus musculus)
Entrez Gene ID 26400
Transcript(s) for this gene NM_001042557 (1720 bp), NM_001164172 (3556 bp), NM_011944 (3515 bp), ENSMUST00000129866, NM_001291777 (1672 bp), NM_001291778 (1563 bp), NM_001291783 (3394 bp)
Official symbol MAP2K7 [Human]
Official name mitogen-activated protein kinase kinase 7
Species Human (Homo sapiens)
Entrez Gene ID 5609
Transcript(s) for this gene NM_145185 (3477 bp), ENST00000498118, NM_001297555 (3525 bp), NM_001297556 (3498 bp), XM_006722800 (1624 bp), XM_005272489 (1603 bp), XM_005272490 (3396 bp), ENST00000397979, ENST00000397981, ENST00000397983
Official symbol Map2k7 [Rat]
Official name mitogen activated protein kinase kinase 7
Species Rat (Rattus norvegicus)
Entrez Gene ID 363855
Transcript(s) for this gene NM_001025425 (1260 bp), XM_006248768 (3523 bp), XM_006248769 (1549 bp), XM_008768985 (1500 bp)
Official symbol Map2k4 [Mouse]
Official name mitogen-activated protein kinase kinase 4
Species Mouse (Mus musculus)
Entrez Gene ID 26398
Transcript(s) for this gene NM_009157 (3756 bp), ENSMUST00000140740, XM_006533369 (3760 bp), XM_006533370 (4761 bp), XM_006533371 (4039 bp), XM_006533372 (3439 bp), XM_006533373 (3516 bp), XM_006533374 (3625 bp), NM_001316367 (3789 bp), NM_001316368 (3614 bp), NM_001316369 (3581 bp), XM_011249033 (3862 bp)
Official symbol MAP2K4 [Human]
Official name mitogen-activated protein kinase kinase 4
Species Human (Homo sapiens)
Entrez Gene ID 6416
Transcript(s) for this gene NM_003010 (3840 bp), ENST00000585076, NM_001281435 (3873 bp), XM_005256753 (3676 bp), XM_005256755 (3658 bp), XM_006721568 (3718 bp), ENST00000353533, ENST00000415385
Official symbol Map2k4 [Rat]
Official name mitogen activated protein kinase kinase 4
Species Rat (Rattus norvegicus)
Entrez Gene ID 287398
Transcript(s) for this gene NM_001030023 (1194 bp), XM_220604 (834 bp)
Official symbol Map2k3 [Mouse]
Official name mitogen-activated protein kinase kinase 3
Species Mouse (Mus musculus)
Entrez Gene ID 26397
Transcript(s) for this gene NM_008928 (2166 bp), ENSMUST00000145828, XM_006533367 (2262 bp), XM_006533368 (2031 bp)
Official symbol MAP2K3 [Human]
Official name mitogen-activated protein kinase kinase 3
Species Human (Homo sapiens)
Entrez Gene ID 5606
Transcript(s) for this gene NM_002756 (2061 bp), NM_145109 (2319 bp), NM_145110 (2191 bp), XM_001130488 (937 bp), ENST00000583508, XM_005256721 (2042 bp), XM_005256722 (2428 bp), XM_005256723 (2100 bp), ENST00000316920, ENST00000342679, ENST00000361818, ENST00000613338, ENST00000627447
Official symbol Map2k3 [Rat]
Official name mitogen activated protein kinase kinase 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 303200
Transcript(s) for this gene NM_001100674 (2356 bp), XM_001077724 (2245 bp), XM_239239 (2245 bp)
Official symbol Mapk13 [Mouse]
Official name mitogen-activated protein kinase 13
Species Mouse (Mus musculus)
Entrez Gene ID 26415
Transcript(s) for this gene NM_011950 (1406 bp), XM_973530 (1646 bp), ENSMUST00000133786, ENSMUST00000124099
Official symbol MAPK13 [Human]
Official name mitogen-activated protein kinase 13
Species Human (Homo sapiens)
Entrez Gene ID 5603
Transcript(s) for this gene NM_002754 (6348 bp), NR_072996 (6196 bp), ENST00000211287, ENST00000373759, ENST00000373766
Official symbol Mapk13 [Rat]
Official name mitogen activated protein kinase 13
Species Rat (Rattus norvegicus)
Entrez Gene ID 29513
Transcript(s) for this gene NM_019231 (1904 bp)
Official symbol Cdkn2a [Mouse]
Official name cyclin-dependent kinase inhibitor 2A
Species Mouse (Mus musculus)
Entrez Gene ID 12578
Transcript(s) for this gene NM_001040654 (850 bp), NM_009877 (929 bp)
Official symbol CDKN2A [Human]
Official name cyclin-dependent kinase inhibitor 2A
Species Human (Homo sapiens)
Entrez Gene ID 1029
Transcript(s) for this gene NM_000077 (1267 bp), NM_001195132 (1464 bp), NM_058195 (1164 bp), NM_058196 (897 bp), NM_058197 (1235 bp), ENST00000582361, XM_005251343 (870 bp), ENST00000304494, ENST00000361570, ENST00000479692, ENST00000494262, ENST00000497750, ENST00000498124, ENST00000498628, ENST00000530628, ENST00000578845, ENST00000579122, ENST00000579755
Official symbol Map2k6 [Mouse]
Official name mitogen-activated protein kinase kinase 6
Species Mouse (Mus musculus)
Entrez Gene ID 26399
Transcript(s) for this gene NM_011943 (2064 bp), ENSMUST00000146540, XM_006533375 (2143 bp), XM_006533376 (4366 bp), XM_006533377 (4453 bp), XM_006533378 (4641 bp), XM_011249034 (4779 bp), XM_011249035 (4390 bp), XM_011249036 (4597 bp)
Official symbol MAP2K6 [Human]
Official name mitogen-activated protein kinase kinase 6
Species Human (Homo sapiens)
Entrez Gene ID 5608
Transcript(s) for this gene NM_002758 (1879 bp), NM_031988 (2820 bp), ENST00000592348, XM_005257515 (1989 bp), XM_005257516 (1806 bp), XM_005257517 (1605 bp), XM_006721975 (1584 bp), ENST00000589647, ENST00000590474, ENST00000613873
Official symbol Map2k6 [Rat]
Official name mitogen-activated protein kinase kinase 6
Species Rat (Rattus norvegicus)
Entrez Gene ID 114495
Transcript(s) for this gene NM_053703 (1690 bp)
Official symbol Ccnb2 [Mouse]
Official name cyclin B2
Species Mouse (Mus musculus)
Entrez Gene ID 12442
Transcript(s) for this gene NM_007630 (1541 bp)
Official symbol CCNB2 [Human]
Official name cyclin B2
Species Human (Homo sapiens)
Entrez Gene ID 9133
Transcript(s) for this gene NM_004701 (1566 bp), ENST00000561077, ENST00000288207, ENST00000559622, ENST00000621385
Official symbol Ccnb2 [Rat]
Official name cyclin B2
Species Rat (Rattus norvegicus)
Entrez Gene ID 363088
Transcript(s) for this gene NM_001009470 (1520 bp)
Official symbol Ccna1 [Mouse]
Official name cyclin A1
Species Mouse (Mus musculus)
Entrez Gene ID 12427
Transcript(s) for this gene NM_007628 (1581 bp), XM_006500948 (1579 bp), XM_006500949 (1578 bp), XM_006500950 (1564 bp), XM_006500951 (1554 bp), XM_006500952 (1543 bp), XM_006500953 (1439 bp), XM_006500954 (1502 bp), XM_006500955 (1275 bp), NM_001305221 (1600 bp), XM_011240003 (1867 bp)
Official symbol CCNA1 [Human]
Official name cyclin A1
Species Human (Homo sapiens)
Entrez Gene ID 8900
Transcript(s) for this gene NM_001111045 (1962 bp), NM_001111046 (1844 bp), NM_001111047 (1841 bp), NM_003914 (1965 bp), ENST00000463403, ENST00000255465, ENST00000440264, ENST00000625767, ENST00000630422
Official symbol Ccna1 [Rat]
Official name cyclin A1
Species Rat (Rattus norvegicus)
Entrez Gene ID 295052
Transcript(s) for this gene NM_001011949 (1761 bp), XM_215565 (1386 bp), XM_006232359 (3161 bp), XM_006232360 (3164 bp), XM_006232361 (3204 bp), XM_006232362 (3031 bp), XM_006232363 (1504 bp), XM_006232364 (2960 bp), XM_008760987 (3254 bp), XM_008760988 (3145 bp)
Official symbol Cdkn2d [Mouse]
Official name cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
Species Mouse (Mus musculus)
Entrez Gene ID 12581
Transcript(s) for this gene NM_009878 (1271 bp), XM_006509968 (1212 bp)
Official symbol CDKN2D [Human]
Official name cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
Species Human (Homo sapiens)
Entrez Gene ID 1032
Transcript(s) for this gene NM_001800 (1416 bp), NM_079421 (1162 bp), ENST00000335766, ENST00000393599
Official symbol Mapk8 [Mouse]
Official name mitogen-activated protein kinase 8
Species Mouse (Mus musculus)
Entrez Gene ID 26419
Transcript(s) for this gene NM_016700 (5770 bp), ENSMUST00000150659, XM_006519030 (4549 bp), XM_006519031 (4550 bp), XM_006519032 (4553 bp), XM_006519033 (3891 bp), NM_001310452 (5626 bp), NM_001310453 (5765 bp), NM_001310454 (5765 bp)
Official symbol MAPK8 [Human]
Official name mitogen-activated protein kinase 8
Species Human (Homo sapiens)
Entrez Gene ID 5599
Transcript(s) for this gene NM_002750 (5676 bp), NM_139046 (5676 bp), NM_139047 (1412 bp), NM_139049 (5671 bp), ENST00000482840, ENST00000469110, NM_001278547 (5854 bp), NM_001278548 (5448 bp), XM_006717917 (5839 bp), XM_006717918 (5844 bp), XM_006717919 (5844 bp), ENST00000360332, ENST00000374174, ENST00000374182, ENST00000374189, ENST00000395611
Official symbol Mapk8 [Rat]
Official name mitogen-activated protein kinase 8
Species Rat (Rattus norvegicus)
Entrez Gene ID 116554
Transcript(s) for this gene XM_001056513 (1376 bp), XM_341399 (1409 bp), NM_053829 (5796 bp)
Official symbol Mapk12 [Mouse]
Official name mitogen-activated protein kinase 12
Species Mouse (Mus musculus)
Entrez Gene ID 29857
Transcript(s) for this gene NM_013871 (1905 bp), XM_006521058 (2848 bp), XM_006521059 (2801 bp), XM_006521060 (2728 bp), XM_006521061 (1266 bp), XM_006521062 (2759 bp), XM_006521063 (1251 bp)
Official symbol MAPK12 [Human]
Official name mitogen-activated protein kinase 12
Species Human (Homo sapiens)
Entrez Gene ID 6300
Transcript(s) for this gene NM_002969 (1778 bp), XM_003403746 (1778 bp), XM_003846644 (2150 bp), ENST00000497738, ENST00000496942, ENST00000482969, XM_005275911 (2305 bp), ENST00000215659, ENST00000395778, ENST00000395780, ENST00000622558
Official symbol Mapk12 [Rat]
Official name mitogen-activated protein kinase 12
Species Rat (Rattus norvegicus)
Entrez Gene ID 60352
Transcript(s) for this gene NM_021746 (1665 bp), XM_008765781 (1661 bp)
Official symbol Pak1 [Mouse]
Official name p21 protein (Cdc42/Rac)-activated kinase 1
Species Mouse (Mus musculus)
Entrez Gene ID 18479
Transcript(s) for this gene NM_011035 (3081 bp), XM_006507434 (3105 bp), XM_006507435 (3810 bp), XM_006507436 (3006 bp), XM_006507437 (3005 bp), XM_011241694 (3102 bp)
Official symbol Lamtor3 [Rat]
Official name late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 362045
Transcript(s) for this gene NM_001008375 (1240 bp), XM_006233383 (1343 bp), XM_006233385 (1288 bp)
Official symbol LAMTOR3 [Human]
Official name late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Species Human (Homo sapiens)
Entrez Gene ID 8649
Transcript(s) for this gene NM_001243736 (4259 bp), NM_021970 (4280 bp), NR_024170 (4234 bp), ENST00000226522, ENST00000499666
Official symbol Max [Rat]
Official name MYC associated factor X
Species Rat (Rattus norvegicus)
Entrez Gene ID 60661
Transcript(s) for this gene NM_022210 (483 bp), XM_006240248 (1943 bp), XM_008764846 (1509 bp)
Official symbol MAX [Human]
Official name MYC associated factor X
Species Human (Homo sapiens)
Entrez Gene ID 4149
Transcript(s) for this gene NM_002382 (2045 bp), NM_145112 (2018 bp), NM_145113 (2146 bp), NM_145114 (937 bp), NM_145116 (575 bp), NM_197957 (560 bp), NM_001271068 (910 bp), NM_001271069 (533 bp), ENST00000246163, ENST00000284165, ENST00000341653, ENST00000358402, ENST00000358664, ENST00000555419, ENST00000555667, ENST00000555932, ENST00000556443, ENST00000556979, ENST00000557277, ENST00000557746, ENST00000618858
Official symbol Max [Mouse]
Official name Max protein
Species Mouse (Mus musculus)
Entrez Gene ID 17187
Transcript(s) for this gene NM_001146176 (1978 bp), NM_008558 (2005 bp), XM_001002021 (1893 bp), XM_991232 (1893 bp), XM_006515523 (1952 bp), XM_006515524 (966 bp)
Official symbol Araf [Rat]
Official name A-Raf proto-oncogene, serine/threonine kinase
Species Rat (Rattus norvegicus)
Entrez Gene ID 64363
Transcript(s) for this gene NM_001033663 (1542 bp), NM_022532 (2350 bp), XM_008773036 (2562 bp)
Official symbol ARAF [Human]
Official name A-Raf proto-oncogene, serine/threonine kinase
Species Human (Homo sapiens)
Entrez Gene ID 369
Transcript(s) for this gene NM_001256196 (2571 bp), NM_001256197 (1408 bp), NM_001654 (2562 bp), ENST00000489496, XM_006724529 (2417 bp), ENST00000290277, ENST00000377039, ENST00000377045
Official symbol Araf [Mouse]
Official name Araf proto-oncogene, serine/threonine kinase
Species Mouse (Mus musculus)
Entrez Gene ID 11836
Transcript(s) for this gene NM_001159645 (1571 bp), NM_009703 (2405 bp), ENSMUST00000152955, XM_006527556 (3498 bp), XM_006527557 (3607 bp), XM_006527558 (1774 bp), XM_011247429 (2375 bp), XM_011247430 (1695 bp)
Official symbol MAPKAPK3 [Human]
Official name mitogen-activated protein kinase-activated protein kinase 3
Species Human (Homo sapiens)
Entrez Gene ID 7867
Transcript(s) for this gene NM_001243925 (2568 bp), NM_001243926 (3047 bp), NM_004635 (2553 bp), ENST00000497283, ENST00000357955, ENST00000446044, ENST00000621469
Official symbol Nfkb1 [Rat]
Official name nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 81736
Transcript(s) for this gene XM_001075876 (3723 bp), XM_342346 (4088 bp), NM_001276711 (3956 bp), XM_006233358 (3612 bp), XM_006233360 (3434 bp)
Official symbol NFKB1 [Human]
Official name nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Species Human (Homo sapiens)
Entrez Gene ID 4790
Transcript(s) for this gene NM_001165412 (4090 bp), NM_003998 (4093 bp), ENST00000513803, XM_005263029 (4007 bp), XM_006714229 (3642 bp), ENST00000226574, ENST00000394820, ENST00000505458, ENST00000600343
Official symbol Nfkb1 [Mouse]
Official name nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Species Mouse (Mus musculus)
Entrez Gene ID 18033
Transcript(s) for this gene NM_008689 (4128 bp), ENSMUST00000150007, XM_006501105 (3394 bp), XM_006501106 (3618 bp), XM_006501107 (3808 bp)
Official symbol Col1a1 [Rat]
Official name collagen, type I, alpha 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 29393
Transcript(s) for this gene NM_053304 (5843 bp), XM_001081230 (5862 bp), XM_213440 (5862 bp)
Official symbol COL1A1 [Human]
Official name collagen, type I, alpha 1
Species Human (Homo sapiens)
Entrez Gene ID 1277
Transcript(s) for this gene NM_000088 (5927 bp), ENST00000511732, ENST00000486572, XM_005257058 (5660 bp), XM_005257059 (5012 bp), XM_006721703 (4598 bp), ENST00000225964
Official symbol Col1a1 [Mouse]
Official name collagen, type I, alpha 1
Species Mouse (Mus musculus)
Entrez Gene ID 12842
Transcript(s) for this gene NM_007742 (5946 bp), ENSMUST00000148593
Official symbol Mapkapk2 [Rat]
Official name mitogen-activated protein kinase-activated protein kinase 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 289014
Transcript(s) for this gene NM_178102 (2909 bp)
Official symbol Pak1 [Rat]
Official name p21 protein (Cdc42/Rac)-activated kinase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 29431
Transcript(s) for this gene NM_017198 (2539 bp), XM_006229752 (3057 bp), XM_006229753 (3054 bp), XM_006229754 (3046 bp)
Official symbol Map2k1 [Rat]
Official name mitogen activated protein kinase kinase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 170851
Transcript(s) for this gene NM_031643 (2151 bp)
Official symbol MAP2K1 [Human]
Official name mitogen-activated protein kinase kinase 1
Species Human (Homo sapiens)
Entrez Gene ID 5604
Transcript(s) for this gene NM_002755 (2603 bp), ENST00000425818, XM_005254541 (2288 bp), XM_006720608 (2537 bp), ENST00000307102, ENST00000566326
Official symbol Map2k1 [Mouse]
Official name mitogen-activated protein kinase kinase 1
Species Mouse (Mus musculus)
Entrez Gene ID 26395
Transcript(s) for this gene NM_008927 (2387 bp), ENSMUST00000152675, XM_006511196 (2239 bp), XM_006511197 (1957 bp)
Official symbol Atf2 [Rat]
Official name activating transcription factor 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 81647
Transcript(s) for this gene NM_031018 (1852 bp)
Official symbol ATF2 [Human]
Official name activating transcription factor 2
Species Human (Homo sapiens)
Entrez Gene ID 1386
Transcript(s) for this gene NM_001256090 (4228 bp), NM_001256091 (4153 bp), NM_001256092 (4096 bp), NM_001256093 (4128 bp), NM_001256094 (1372 bp), NM_001880 (4193 bp), NR_045768 (4390 bp), NR_045769 (4422 bp), NR_045770 (4275 bp), NR_045771 (4267 bp), NR_045772 (4205 bp), NR_045773 (4170 bp), NR_045774 (4078 bp), ENST00000264110, ENST00000345739, ENST00000392544, ENST00000409437, ENST00000409499, ENST00000409635, ENST00000409833, ENST00000426833, ENST00000538946
Official symbol Atf2 [Mouse]
Official name activating transcription factor 2
Species Mouse (Mus musculus)
Entrez Gene ID 11909
Transcript(s) for this gene NM_001025093 (4300 bp), NM_009715 (4203 bp), ENSMUST00000156455, NM_001284369 (4140 bp), NM_001284370 (3679 bp), NM_001284371 (3616 bp), NM_001284372 (4006 bp), NM_001284373 (3943 bp), NM_001284374 (4025 bp), NM_001284376 (4182 bp), XM_006498592 (4223 bp), XM_006498593 (4356 bp), XM_006498594 (4252 bp), XM_006498595 (4105 bp), XM_006498596 (3984 bp), XM_006498597 (3886 bp), XM_006498598 (4117 bp), XM_006498599 (3823 bp)
Official symbol Nras [Rat]
Official name neuroblastoma RAS viral oncogene homolog
Species Rat (Rattus norvegicus)
Entrez Gene ID 24605
Transcript(s) for this gene NM_080766 (1326 bp), XM_006233059 (4223 bp)
Official symbol Mapk9 [Rat]
Official name mitogen-activated protein kinase 9
Species Rat (Rattus norvegicus)
Entrez Gene ID 50658
Transcript(s) for this gene NM_017322 (3711 bp), NM_001270544 (3711 bp), NM_001270545 (3716 bp), XM_006246317 (4640 bp), XM_006246318 (2083 bp)
Official symbol MAPK9 [Human]
Official name mitogen-activated protein kinase 9
Species Human (Homo sapiens)
Entrez Gene ID 5601
Transcript(s) for this gene NM_001135044 (2370 bp), NM_002752 (4336 bp), NM_139068 (4341 bp), NM_139069 (4341 bp), NM_139070 (4336 bp), ENST00000524170, XM_005265940 (4465 bp), XM_006714891 (4375 bp), ENST00000343111, ENST00000347470, ENST00000393360, ENST00000397072, ENST00000425491, ENST00000452135, ENST00000455781, ENST00000539014
Official symbol Mapk9 [Mouse]
Official name mitogen-activated protein kinase 9
Species Mouse (Mus musculus)
Entrez Gene ID 26420
Transcript(s) for this gene NM_001163671 (4677 bp), NM_001163672 (4682 bp), NM_016961 (4682 bp), NM_207692 (4677 bp), ENSMUST00000151695, XM_006533379 (4616 bp)
Official symbol Ccnd3 [Rat]
Official name cyclin D3
Species Rat (Rattus norvegicus)
Entrez Gene ID 25193
Transcript(s) for this gene NM_012766 (1843 bp), XM_008766836 (1661 bp)
Official symbol Cdkn1a [Rat]
Official name cyclin-dependent kinase inhibitor 1A
Species Rat (Rattus norvegicus)
Entrez Gene ID 114851
Transcript(s) for this gene NM_080782 (1894 bp), XM_006256128 (1937 bp)
Official symbol Hspa5 [Rat]
Official name heat shock protein 5
Species Rat (Rattus norvegicus)
Entrez Gene ID 25617
Transcript(s) for this gene NM_013083 (2580 bp)
Official symbol HSPA5 [Human]
Official name heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
Species Human (Homo sapiens)
Entrez Gene ID 3309
Transcript(s) for this gene NM_005347 (3973 bp), ENST00000324460
Official symbol Hspa5 [Mouse]
Official name heat shock protein 5
Species Mouse (Mus musculus)
Entrez Gene ID 14828
Transcript(s) for this gene NM_001163434 (2534 bp), NM_022310 (2616 bp), ENSMUST00000155595
Official symbol Ccnd1 [Rat]
Official name cyclin D1
Species Rat (Rattus norvegicus)
Entrez Gene ID 58919
Transcript(s) for this gene NM_171992 (3809 bp), XM_008760168 (4050 bp)
Official symbol CCND1 [Human]
Official name cyclin D1
Species Human (Homo sapiens)
Entrez Gene ID 595
Transcript(s) for this gene NM_053056 (4304 bp), ENST00000545484, XM_006718653 (4104 bp), ENST00000227507, ENST00000536559
Official symbol Ccnd1 [Mouse]
Official name cyclin D1
Species Mouse (Mus musculus)
Entrez Gene ID 12443
Transcript(s) for this gene NM_007631 (3796 bp), XM_001002530 (2213 bp), XM_001002537 (2565 bp), ENSMUST00000135985, XM_006508466 (1177 bp), XM_011241977 (3874 bp)
Official symbol Ccnd2 [Rat]
Official name cyclin D2
Species Rat (Rattus norvegicus)
Entrez Gene ID 64033
Transcript(s) for this gene NM_022267 (1415 bp)
Official symbol Egr1 [Rat]
Official name early growth response 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24330
Transcript(s) for this gene NM_012551 (1527 bp)
Official symbol EGR1 [Human]
Official name early growth response 1
Species Human (Homo sapiens)
Entrez Gene ID 1958
Transcript(s) for this gene NM_001964 (3136 bp), ENST00000239938
Official symbol Egr1 [Mouse]
Official name early growth response 1
Species Mouse (Mus musculus)
Entrez Gene ID 13653
Transcript(s) for this gene NM_007913 (3072 bp)
Official symbol Mos [Rat]
Official name Moloney sarcoma oncogene
Species Rat (Rattus norvegicus)
Entrez Gene ID 24559
Transcript(s) for this gene NM_020102 (1308 bp)
Official symbol Dlk1 [Rat]
Official name delta like non-canonical Notch ligand 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 114587
Transcript(s) for this gene NM_053744 (1538 bp), XM_008764917 (1434 bp)
Official symbol DLK1 [Human]
Official name delta-like 1 homolog (Drosophila)
Species Human (Homo sapiens)
Entrez Gene ID 8788
Transcript(s) for this gene NM_001032997 (1352 bp), NM_003836 (1599 bp), ENST00000555747, ENST00000331224, ENST00000341267, ENST00000556051
Official symbol Dlk1 [Mouse]
Official name delta-like 1 homolog (Drosophila)
Species Mouse (Mus musculus)
Entrez Gene ID 13386
Transcript(s) for this gene NM_001190703 (4054 bp), NM_001190704 (4120 bp), NM_001190705 (4186 bp), NM_010052 (4339 bp), NR_033813 (4679 bp), XM_006515457 (1409 bp), XM_006544937 (1409 bp), ENSMUST00000174539, XM_011243992 (1569 bp), XM_011251520 (1569 bp)
Official symbol Ets1 [Rat]
Official name v-ets avian erythroblastosis virus E26 oncogene homolog 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24356
Transcript(s) for this gene NM_012555 (5031 bp), XM_006242752 (4818 bp)
Official symbol TXN [Human]
Official name thioredoxin
Species Human (Homo sapiens)
Entrez Gene ID 7295
Transcript(s) for this gene NM_001244938 (826 bp), NM_003329 (886 bp), ENST00000487892, XM_006717276 (907 bp), ENST00000374515, ENST00000374517
Official symbol Txn1 [Mouse]
Official name thioredoxin 1
Species Mouse (Mus musculus)
Entrez Gene ID 22166
Transcript(s) for this gene NM_011660 (1051 bp)
Official symbol Kcnh8 [Rat]
Official name potassium voltage-gated channel subfamily H member 8
Species Rat (Rattus norvegicus)
Entrez Gene ID 246325
Transcript(s) for this gene NM_145095 (3739 bp)
Official symbol Raf1 [Rat]
Official name v-raf-leukemia viral oncogene 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24703
Transcript(s) for this gene NM_012639 (2970 bp), XM_008763217 (3075 bp), XM_008763218 (3255 bp)
Official symbol RAF1 [Human]
Official name Raf-1 proto-oncogene, serine/threonine kinase
Species Human (Homo sapiens)
Entrez Gene ID 5894
Transcript(s) for this gene NM_002880 (3291 bp), ENST00000494557, XM_005265355 (2996 bp), XM_005265357 (3085 bp), XM_005265358 (3155 bp), XM_005265359 (3056 bp), XM_005265360 (1895 bp), ENST00000251849, ENST00000442415
Official symbol Raf1 [Mouse]
Official name v-raf-leukemia viral oncogene 1
Species Mouse (Mus musculus)
Entrez Gene ID 110157
Transcript(s) for this gene NM_029780 (3066 bp), ENSMUST00000130528, XM_006505363 (3607 bp), XM_006505364 (2984 bp), XM_006505365 (2924 bp)
Official symbol CREB1 [Human]
Official name cAMP responsive element binding protein 1
Species Human (Homo sapiens)
Entrez Gene ID 1385
Transcript(s) for this gene NM_004379 (9752 bp), NM_134442 (9794 bp), ENST00000494983, XR_241289 (6030 bp), XR_241290 (7804 bp), XR_241292 (7689 bp), ENST00000353267, ENST00000430624, ENST00000432329
Official symbol Creb1 [Mouse]
Official name cAMP responsive element binding protein 1
Species Mouse (Mus musculus)
Entrez Gene ID 12912
Transcript(s) for this gene NM_001037726 (8267 bp), NM_009952 (8431 bp), NM_133828 (8389 bp), XM_006495650 (6715 bp), XM_006495651 (6673 bp), XM_006495652 (6581 bp), XM_006495653 (6529 bp), XM_006495654 (6487 bp), XM_006495655 (8423 bp), XM_011238424 (6736 bp), XM_011238425 (8094 bp)
Official symbol Creb1 [Rat]
Official name cAMP responsive element binding protein 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 81646
Transcript(s) for this gene NM_031017 (1125 bp), NM_134443 (1023 bp), XM_006245065 (6691 bp), XM_006245066 (6856 bp), XM_006245067 (6596 bp), XM_006245068 (6543 bp), XM_006245069 (7193 bp), XM_006245070 (6063 bp), XM_008767138 (9047 bp), XM_008767139 (6917 bp)
Official symbol Elk1 [Mouse]
Official name ELK1, member of ETS oncogene family
Species Mouse (Mus musculus)
Entrez Gene ID 13712
Transcript(s) for this gene NM_007922 (3548 bp), ENSMUST00000148133
Official symbol KRAS [Human]
Official name Kirsten rat sarcoma viral oncogene homolog
Species Human (Homo sapiens)
Entrez Gene ID 3845
Transcript(s) for this gene NM_004985 (5765 bp), NM_033360 (5889 bp), XM_006719069 (812 bp), ENST00000256078, ENST00000311936, ENST00000556131, ENST00000557334
Official symbol Nras [Mouse]
Official name neuroblastoma ras oncogene
Species Mouse (Mus musculus)
Entrez Gene ID 18176
Transcript(s) for this gene NM_010937 (4470 bp), XM_006501118 (4544 bp), XM_006501119 (4502 bp), XM_006501120 (4332 bp), XM_006501121 (4380 bp), XM_006501122 (4340 bp), XM_006501123 (4418 bp)
Official symbol Kras [Mouse]
Official name Kirsten rat sarcoma viral oncogene homolog
Species Mouse (Mus musculus)
Entrez Gene ID 16653
Transcript(s) for this gene NM_021284 (4670 bp), ENSMUST00000149314, XM_006506918 (4804 bp), XM_006506919 (4850 bp), XM_006536039 (4818 bp), XM_006536040 (4811 bp)
Official symbol Kras [Rat]
Official name KRAS proto-oncogene, GTPase
Species Rat (Rattus norvegicus)
Entrez Gene ID 24525
Transcript(s) for this gene NM_031515 (661 bp), XM_008763352 (3247 bp), XM_008763353 (4043 bp), XM_008763354 (4048 bp), XM_008763355 (6893 bp)
Official symbol Map3k4 [Mouse]
Official name mitogen-activated protein kinase kinase kinase 4
Species Mouse (Mus musculus)
Entrez Gene ID 26407
Transcript(s) for this gene NM_011948 (5305 bp), XM_006523329 (5295 bp), XM_006523330 (5265 bp), XM_006523331 (4051 bp)
Official symbol MAP3K4 [Human]
Official name mitogen-activated protein kinase kinase kinase 4
Species Human (Homo sapiens)
Entrez Gene ID 4216
Transcript(s) for this gene NM_005922 (5564 bp), NM_006724 (5414 bp), ENST00000544733, NM_001291958 (5662 bp), NM_001301072 (5552 bp), XM_005266989 (5328 bp), XM_005266988 (5478 bp), XR_245517 (5581 bp), ENST00000348824, ENST00000366919, ENST00000366920, ENST00000392142
Official symbol Map3k4 [Rat]
Official name mitogen activated protein kinase kinase kinase 4
Species Rat (Rattus norvegicus)
Entrez Gene ID 308106
Transcript(s) for this gene NM_001107456 (4908 bp), XM_001062918 (5330 bp), XM_001063040 (5492 bp), XM_001063095 (5294 bp), XM_001063151 (5456 bp), XM_217804 (5492 bp), XM_006227872 (5465 bp), XM_006227873 (5303 bp), XM_006227874 (5222 bp)
Official symbol Mapk8ip3 [Mouse]
Official name mitogen-activated protein kinase 8 interacting protein 3
Species Mouse (Mus musculus)
Entrez Gene ID 30957
Transcript(s) for this gene NM_001163447 (5576 bp), NM_001163448 (5551 bp), NM_001163449 (5510 bp), NM_001163450 (5486 bp), NM_001163451 (5483 bp), NM_001163453 (5468 bp), NM_013931 (5596 bp), ENSMUST00000156663
Official symbol Mapk8ip3 [Rat]
Official name mitogen-activated protein kinase 8 interacting protein 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 302983
Transcript(s) for this gene NM_001100673 (3969 bp), XM_001057684 (5487 bp), XM_001057810 (5445 bp), XM_001060342 (5445 bp), XM_220232 (5487 bp), XM_006245953 (5540 bp), XM_006245954 (5537 bp), XM_006245955 (5515 bp), XM_006245956 (5513 bp), XM_006245957 (5513 bp), XM_006245958 (5494 bp), XM_006245959 (5447 bp), XM_006245960 (5444 bp), XM_006245961 (5422 bp), XM_006245962 (5419 bp), XM_006245963 (5404 bp), XM_008767567 (5521 bp), XM_008767568 (5212 bp), XM_008767569 (4749 bp)
Official symbol Sfn [Mouse]
Official name stratifin
Species Mouse (Mus musculus)
Entrez Gene ID 55948
Transcript(s) for this gene NM_018754 (1616 bp)
Official symbol SFN [Human]
Official name stratifin
Species Human (Homo sapiens)
Entrez Gene ID 2810
Transcript(s) for this gene NM_006142 (1336 bp), ENST00000339276
Official symbol Mapk8ip2 [Mouse]
Official name mitogen-activated protein kinase 8 interacting protein 2
Species Mouse (Mus musculus)
Entrez Gene ID 60597
Transcript(s) for this gene NM_021921 (3553 bp)
Official symbol MAPK8IP2 [Human]
Official name mitogen-activated protein kinase 8 interacting protein 2
Species Human (Homo sapiens)
Entrez Gene ID 23542
Transcript(s) for this gene NM_012324 (3395 bp), NM_016431 (3183 bp), NM_139124 (2271 bp), ENST00000329492
Official symbol Mapk8ip2 [Rat]
Official name mitogen-activated protein kinase 8 interacting protein 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 315220
Transcript(s) for this gene XM_001055248 (5419 bp), XM_235565 (5419 bp)
Official symbol Mapkapk2 [Mouse]
Official name MAP kinase-activated protein kinase 2
Species Mouse (Mus musculus)
Entrez Gene ID 17164
Transcript(s) for this gene NM_008551 (2884 bp), XM_977114 (713 bp), XM_977149 (2196 bp), XM_977187 (2528 bp), XM_011247933 (2370 bp)
Official symbol MAPKAPK2 [Human]
Official name mitogen-activated protein kinase-activated protein kinase 2
Species Human (Homo sapiens)
Entrez Gene ID 9261
Transcript(s) for this gene NM_004759 (3534 bp), NM_032960 (2997 bp), ENST00000493447, XM_005273353 (3096 bp), ENST00000294981, ENST00000367103
Official symbol Mknk1 [Mouse]
Official name MAP kinase-interacting serine/threonine kinase 1
Species Mouse (Mus musculus)
Entrez Gene ID 17346
Transcript(s) for this gene NM_021461 (2554 bp), ENSMUST00000155412, NM_001285487 (2704 bp), NM_001285488 (2598 bp), XM_006502822 (2673 bp), XM_006502823 (2563 bp), XM_006502824 (2584 bp), XM_006502825 (2731 bp), XM_006502826 (2842 bp), XM_006502827 (1512 bp)
Official symbol MKNK1 [Human]
Official name MAP kinase interacting serine/threonine kinase 1
Species Human (Homo sapiens)
Entrez Gene ID 8569
Transcript(s) for this gene NM_001135553 (2704 bp), NM_003684 (2827 bp), NM_198973 (2618 bp), NR_024174 (2575 bp), NR_024176 (2721 bp), XM_006710999 (2506 bp), XM_006711000 (2640 bp), XM_006711001 (2732 bp), XM_006711002 (2536 bp), XM_006711003 (2701 bp), XM_006711004 (2885 bp), XM_006711005 (2419 bp), XM_006711006 (2560 bp), XM_006711007 (2532 bp), XM_006711008 (2787 bp), XM_006711009 (3028 bp), XM_006711010 (2927 bp), XM_006711011 (2462 bp), XM_006711012 (2615 bp), XM_006711013 (2565 bp), XM_006711014 (2556 bp), XM_006711015 (2627 bp), ENST00000341183, ENST00000371945, ENST00000371946, ENST00000428112, ENST00000465783
Official symbol Mknk1 [Rat]
Official name MAP kinase-interacting serine/threonine kinase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 500526
Transcript(s) for this gene NM_001044267 (1935 bp), XM_001064399 (2334 bp), XM_001064462 (2500 bp), XM_575887 (1701 bp), XM_006238694 (3880 bp), XM_006238695 (4818 bp), XM_006238696 (2695 bp), XM_006238697 (2647 bp), XM_006238698 (2588 bp), XM_006238699 (3814 bp)
Official symbol Ccnd3 [Mouse]
Official name cyclin D3
Species Mouse (Mus musculus)
Entrez Gene ID 12445
Transcript(s) for this gene NM_001081635 (2086 bp), NM_001081636 (2131 bp), NM_007632 (1992 bp), XM_001003930 (1963 bp), XM_001003934 (2006 bp), XM_001003940 (2163 bp), XM_001003943 (2245 bp), ENSMUST00000183061, XM_006523552 (1682 bp), XM_006523553 (1521 bp), XM_011246260 (2451 bp), XM_011246261 (2579 bp), XM_011246262 (1663 bp)
Official symbol CCND3 [Human]
Official name cyclin D3
Species Human (Homo sapiens)
Entrez Gene ID 896
Transcript(s) for this gene NM_001136017 (2099 bp), NM_001136125 (1886 bp), NM_001136126 (1883 bp), NM_001760 (2102 bp), ENST00000514382, NM_001287427 (2585 bp), NM_001287434 (2065 bp), ENST00000372987, ENST00000372988, ENST00000372991, ENST00000414200, ENST00000415497, ENST00000510503, ENST00000511642, ENST00000616010
Official symbol BRAF [Human]
Official name B-Raf proto-oncogene, serine/threonine kinase
Species Human (Homo sapiens)
Entrez Gene ID 673
Transcript(s) for this gene NM_004333 (2949 bp), ENST00000469930, XM_005250045 (9472 bp), XM_005250046 (9318 bp), ENST00000288602
Official symbol Map2k2 [Mouse]
Official name mitogen-activated protein kinase kinase 2
Species Mouse (Mus musculus)
Entrez Gene ID 26396
Transcript(s) for this gene NM_023138 (2387 bp), XM_987766 (1067 bp), ENSMUST00000128937, ENSMUST00000123241, XM_006513682 (2405 bp), XM_006513683 (2189 bp), XM_006513684 (2537 bp)
Official symbol MAP2K2 [Human]
Official name mitogen-activated protein kinase kinase 2
Species Human (Homo sapiens)
Entrez Gene ID 5605
Transcript(s) for this gene NM_030662 (1759 bp), ENST00000602167, XM_006722799 (1515 bp), ENST00000262948, ENST00000394867
Official symbol Map2k2 [Rat]
Official name mitogen activated protein kinase kinase 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 58960
Transcript(s) for this gene NM_133283 (1376 bp), XM_006240987 (1571 bp)
Official symbol Crebbp [Mouse]
Official name CREB binding protein
Species Mouse (Mus musculus)
Entrez Gene ID 12914
Transcript(s) for this gene NM_001025432 (7507 bp), XM_148699 (5867 bp), XM_489496 (2805 bp), XM_489497 (4498 bp), XM_006521751 (10301 bp), XM_006521752 (10286 bp), XM_006521753 (10187 bp), XM_006521754 (10157 bp)
Official symbol CREBBP [Human]
Official name CREB binding protein
Species Human (Homo sapiens)
Entrez Gene ID 1387
Transcript(s) for this gene NM_001079846 (10083 bp), NM_004380 (10197 bp), ENST00000576720, XM_005255124 (9999 bp), XM_005255125 (9627 bp), XM_006720848 (9783 bp), ENST00000262367, ENST00000382070
Official symbol Crebbp [Rat]
Official name CREB binding protein
Species Rat (Rattus norvegicus)
Entrez Gene ID 54244
Transcript(s) for this gene NM_133381 (10103 bp), XM_008767524 (7157 bp)
Official symbol Rac1 [Mouse]
Official name RAS-related C3 botulinum substrate 1
Species Mouse (Mus musculus)
Entrez Gene ID 19353
Transcript(s) for this gene NM_009007 (2284 bp), ENSMUST00000145709, XM_006504667 (2449 bp)
Official symbol RAC1 [Human]
Official name ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
Species Human (Homo sapiens)
Entrez Gene ID 5879
Transcript(s) for this gene NM_006908 (2341 bp), NM_018890 (2398 bp), NM_198829 (2413 bp), ENST00000497741, ENST00000348035, ENST00000356142
Official symbol Rac1 [Rat]
Official name ras-related C3 botulinum toxin substrate 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 363875
Transcript(s) for this gene NM_134366 (792 bp), XM_008768986 (2126 bp)
Official symbol Ets1 [Mouse]
Official name E26 avian leukemia oncogene 1, 5' domain
Species Mouse (Mus musculus)
Entrez Gene ID 23871
Transcript(s) for this gene NM_001038642 (4799 bp), NM_011808 (5060 bp), ENSMUST00000184110, XM_006510269 (4969 bp)
Official symbol ETS1 [Human]
Official name v-ets avian erythroblastosis virus E26 oncogene homolog 1
Species Human (Homo sapiens)
Entrez Gene ID 2113
Transcript(s) for this gene NM_001143820 (5143 bp), NM_001162422 (4594 bp), NM_005238 (5242 bp), ENST00000530924, XM_005271428 (4862 bp), ENST00000319397, ENST00000392668, ENST00000526145, ENST00000531611, ENST00000535549
Official symbol Mapk14 [Mouse]
Official name mitogen-activated protein kinase 14
Species Mouse (Mus musculus)
Entrez Gene ID 26416
Transcript(s) for this gene NM_001168508 (3560 bp), NM_001168513 (3161 bp), NM_001168514 (3605 bp), NM_011951 (3560 bp), ENSMUST00000151613, XM_006524304 (1268 bp), XM_006524305 (1175 bp)
Official symbol MAPK14 [Human]
Official name mitogen-activated protein kinase 14
Species Human (Homo sapiens)
Entrez Gene ID 1432
Transcript(s) for this gene NM_001315 (4353 bp), NM_139012 (4353 bp), NM_139013 (1431 bp), NM_139014 (4274 bp), ENST00000496250, XM_006714998 (3351 bp), ENST00000229794, ENST00000229795, ENST00000310795, ENST00000468133, ENST00000622903
Official symbol Mapk14 [Rat]
Official name mitogen activated protein kinase 14
Species Rat (Rattus norvegicus)
Entrez Gene ID 81649
Transcript(s) for this gene NM_031020 (3452 bp), XM_006256142 (3138 bp)
Official symbol Jun [Mouse]
Official name jun proto-oncogene
Species Mouse (Mus musculus)
Entrez Gene ID 16476
Transcript(s) for this gene NM_010591 (3187 bp)
Official symbol JUN [Human]
Official name jun proto-oncogene
Species Human (Homo sapiens)
Entrez Gene ID 3725
Transcript(s) for this gene NM_002228 (3338 bp), ENST00000371222
Official symbol Jun [Rat]
Official name jun proto-oncogene
Species Rat (Rattus norvegicus)
Entrez Gene ID 24516
Transcript(s) for this gene NM_021835 (3107 bp)
Official symbol Ets2 [Mouse]
Official name E26 avian leukemia oncogene 2, 3' domain
Species Mouse (Mus musculus)
Entrez Gene ID 23872
Transcript(s) for this gene NM_011809 (3560 bp), ENSMUST00000145509
Official symbol ETS2 [Human]
Official name v-ets avian erythroblastosis virus E26 oncogene homolog 2
Species Human (Homo sapiens)
Entrez Gene ID 2114
Transcript(s) for this gene NM_001256295 (3954 bp), NM_005239 (3784 bp), XM_005260935 (3839 bp), ENST00000360214, ENST00000360938
Official symbol Mapkapk5 [Mouse]
Official name MAP kinase-activated protein kinase 5
Species Mouse (Mus musculus)
Entrez Gene ID 17165
Transcript(s) for this gene NM_010765 (2229 bp), XM_990515 (5134 bp), ENSMUST00000154628
Official symbol Mapkapk5 [Rat]
Official name mitogen-activated protein kinase-activated protein kinase 5
Species Rat (Rattus norvegicus)
Entrez Gene ID 498183
Transcript(s) for this gene NM_001025761 (1330 bp), NM_001164043 (1699 bp), XM_573398 (1746 bp)
Official symbol Rb1 [Mouse]
Official name retinoblastoma 1
Species Mouse (Mus musculus)
Entrez Gene ID 19645
Transcript(s) for this gene NM_009029 (4642 bp), ENSMUST00000170967, XM_006518731 (2420 bp), XR_383150 (3088 bp), XR_383151 (2889 bp)
Official symbol RB1 [Human]
Official name retinoblastoma 1
Species Human (Homo sapiens)
Entrez Gene ID 5925
Transcript(s) for this gene NM_000321 (4772 bp), ENST00000531171, ENST00000267163
Official symbol Rb1 [Rat]
Official name retinoblastoma 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24708
Transcript(s) for this gene NM_017045 (4711 bp), XM_001071121 (4566 bp), XM_344434 (4694 bp)
Official symbol Ccnd2 [Mouse]
Official name cyclin D2
Species Mouse (Mus musculus)
Entrez Gene ID 12444
Transcript(s) for this gene NM_009829 (5772 bp), XM_006505457 (6223 bp), XM_006505458 (6205 bp), XM_006505459 (6266 bp), XM_006505460 (6097 bp)
Official symbol CCND2 [Human]
Official name cyclin D2
Species Human (Homo sapiens)
Entrez Gene ID 894
Transcript(s) for this gene NM_001759 (6531 bp), ENST00000541542, XM_005253813 (1076 bp), ENST00000261254
Official symbol Lamtor3 [Mouse]
Official name late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Species Mouse (Mus musculus)
Entrez Gene ID 56692
Transcript(s) for this gene NM_019920 (1263 bp)
Official symbol Egfr [Mouse]
Official name epidermal growth factor receptor
Species Mouse (Mus musculus)
Entrez Gene ID 13649
Transcript(s) for this gene NM_007912 (2678 bp), NM_207655 (5983 bp), ENSMUST00000139722, XM_006514491 (6041 bp)
Official symbol EGFR [Human]
Official name epidermal growth factor receptor
Species Human (Homo sapiens)
Entrez Gene ID 1956
Transcript(s) for this gene NM_005228 (5616 bp), NM_201282 (2239 bp), NM_201283 (1595 bp), NM_201284 (2865 bp), ENST00000485503, ENST00000275493, ENST00000342916, ENST00000344576, ENST00000420316, ENST00000442591, ENST00000454757, ENST00000455089
Official symbol Egfr [Rat]
Official name epidermal growth factor receptor
Species Rat (Rattus norvegicus)
Entrez Gene ID 24329
Transcript(s) for this gene NM_031507 (4161 bp), XM_008770416 (9579 bp), XM_008770417 (9537 bp), XM_008770418 (3800 bp)
Official symbol NRAS [Human]
Official name neuroblastoma RAS viral (v-ras) oncogene homolog
Species Human (Homo sapiens)
Entrez Gene ID 4893
Transcript(s) for this gene NM_002524 (4454 bp), ENST00000369535
Official symbol PAK1 [Human]
Official name p21 protein (Cdc42/Rac)-activated kinase 1
Species Human (Homo sapiens)
Entrez Gene ID 5058
Transcript(s) for this gene NM_001128620 (3484 bp), NM_002576 (3435 bp), ENST00000533568, XM_005274025 (3135 bp), XM_006718572 (3081 bp), XM_006718573 (3204 bp), XM_006718574 (3158 bp), XM_006718575 (2995 bp), XM_006718576 (3425 bp), ENST00000278568, ENST00000356341, ENST00000528203, ENST00000530617
Official symbol CDKN1A [Human]
Official name cyclin-dependent kinase inhibitor 1A (p21, Cip1)
Species Human (Homo sapiens)
Entrez Gene ID 1026
Transcript(s) for this gene NM_000389 (2175 bp), NM_001220777 (2119 bp), NM_001220778 (2284 bp), NM_078467 (2122 bp), NR_037150 (2327 bp), NR_037151 (2285 bp), NR_037152 (2120 bp), ENST00000478800, NM_001291549 (2325 bp), ENST00000244741, ENST00000373711, ENST00000405375, ENST00000448526, ENST00000615513
Official symbol Mos [Mouse]
Official name Moloney sarcoma oncogene
Species Mouse (Mus musculus)
Entrez Gene ID 17451
Transcript(s) for this gene NM_020021 (1449 bp), XM_973427 (1142 bp)
Official symbol MOS [Human]
Official name v-mos Moloney murine sarcoma viral oncogene homolog
Species Human (Homo sapiens)
Entrez Gene ID 4342
Transcript(s) for this gene NM_005372 (1041 bp), ENST00000311923
Official symbol Ets2 [Rat]
Official name ETS proto-oncogene 2, transcription factor
Species Rat (Rattus norvegicus)
Entrez Gene ID 304063
Transcript(s) for this gene NM_001107107 (3614 bp), XM_001053903 (4013 bp), XM_239510 (4013 bp), XM_006248177 (3831 bp)
Official symbol Sfn [Rat]
Official name stratifin
Species Rat (Rattus norvegicus)
Entrez Gene ID 313017
Transcript(s) for this gene XM_001065560 (1516 bp), XM_232745 (1077 bp), XM_003750048 (1516 bp)
Official symbol Mapk1 [Rat]
Official name mitogen activated protein kinase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 116590
Transcript(s) for this gene NM_053842 (1467 bp), XM_006248658 (4970 bp), XM_006248659 (1470 bp), XM_008768848 (3690 bp)
Official symbol Kcnn1 [Rat]
Official name potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 54261
Transcript(s) for this gene NM_019313 (1611 bp), XM_006252933 (2847 bp)
Official symbol Cdk6 [Rat]
Official name cyclin-dependent kinase 6
Species Rat (Rattus norvegicus)
Entrez Gene ID 114483
Transcript(s) for this gene NM_001191861 (1503 bp), XM_001068770 (1503 bp), XM_342638 (1503 bp), XM_006236019 (5879 bp), XM_006236020 (5813 bp), XM_006236021 (5755 bp), XM_008762679 (5730 bp)
Official symbol Cdkn2a [Rat]
Official name cyclin-dependent kinase inhibitor 2A
Species Rat (Rattus norvegicus)
Entrez Gene ID 25163
Transcript(s) for this gene NM_031550 (707 bp)
Official symbol Cdkn1c [Rat]
Official name cyclin-dependent kinase inhibitor 1C
Species Rat (Rattus norvegicus)
Entrez Gene ID 246060
Transcript(s) for this gene NM_001033757 (2081 bp), NM_001033758 (2045 bp), NM_182735 (1910 bp), XM_008760076 (1966 bp), XM_008760077 (1967 bp), XM_008760078 (1926 bp), XM_008760079 (1924 bp)
Official symbol Cdkn2d [Rat]
Official name similar to cyclin-dependent kinase inhibitor 2D
Species Rat (Rattus norvegicus)
Entrez Gene ID 494444
Transcript(s) for this gene NM_001009719 (1234 bp)

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