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Cignal Reporter Assay Kits

For rapid, sensitive, and quantitative assessment of signal transduction pathway activation

  • Rapid analysis of signal transduction pathway regulation
  • Exceptional sensitivity and specificity
  • Transfection-ready constructs
  • Includes positive and negative controls
  • Real-time live cell quantification (GFP format)

Cignal Reporter Assays provided in the Cignal Reporter Assay Kit enable rapid, sensitive, and quantitative assessment of signal transduction pathway activation by measuring the activities of downstream transcription factors. Two reporter systems are available: dual-luciferase format and GFP format.

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Cignal Reporter Assay Kits are intended for molecular biology applications. These products are not intended for the diagnosis, prevention, or treatment of a disease.


0
TNFα activates NFkB signaling activity in a dose-dependent manner.
293 H cells were transfected with Cignal NFkB Reporter Assay, negative or positive control. After 24 hours, cells were treated with different doses of hTNFα for a further 24 hours. Dual-luciferase assays were performed, and reporter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and standard deviation is shown.
1
Assessing RNA interference phenotypes.

Cignal p53 Reporter Assays showed that p53 siRNA treatment abolished p53 transcription activity. HCT 116 cells were transfected with p53 reporter, negative control, and positive control, together with p53 siRNA or negative control siRNA. Dual-luciferase assays were performed. Reporter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and the standard deviation is shown.

2
Assessing overexpression phenotypes.

Cignal RBP-Jκ Reporter Assay showed upregulation of Notch signaling activity after overexpression of activated Notch1. 293 H cells were transfected with RBP-Jκ reporter, negative control, and positive control. After 24 hours, cells were infected with 100 MOI of recombinant adenoviruses expressing activated Notch1 (Ad-NICD) or 100 MOI of recombinant adenovirus expressing GFP (Ad-GFP) for another 18 hours. Dual-luciferase assays were performed. Reporter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and the standard deviation is shown.

3
Verification of small molecule drug candidate.

Cignal Retinoic Acid Response Element (RARE) Reporter Assay reported elevated retinoic acid receptor pathway activity after the treatment of all trans-retinoic acid (ATRA). CHO-K1 cells were transfected with RARE reporter, negative control, and positive control. After 16 hours, medium was changed to assay medium. After 24 hours, cells were treated with 1 µM all trans-rectinoic acid (ATRA) for 6 hours. Dual-luciferase assay was performed, and promoter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate and the standard deviation is shown.

4
Cignal Reporter Assay shows that hTNFa activated NFkB signaling pathway.
293 H cells were transfected with the Cignal NFkB-GFP Reporter Assay or negative control. After 16 hours, medium was changed to assay medium. After 24 hours, cells were treated with 10 ng/ml TNFα. After 18 hours, medium was removed from the wells and fluorescence activity was measured using a fluorometer. The fluorescence activity present in treated and nontreated negative control wells was subtracted from the fluorescence activity in treated and nontreated Cignal NFkB-GFP Reporter Assay wells and relative fluorescence activities expressed as arbitrary units. Experiments were performed in triplicate and the standard deviations are shown.
5
Cignal Reporter Assay measures activation of serum response factor (SRF) transcription activity.

293 H cells were transfected with the Cignal SRF-GFP Reporter Assay or negative control. After 16 hours, medium was changed to assay medium. After 24 hours, cells were treated with 10 ng/ml PMA and 10% serum. After 18 hours, medium was removed from the wells and fluorescence activity was measured using a fluorometer. The fluorescence activity present in treated and nontreated negative control wells was subtracted from the fluorescence activity in treated and nontreated Cignal SRF-GFP Reporter Assay wells and relative fluorescence activities expressed as arbitrary units. Experiments were performed in triplicate and the standard deviations are shown.

6
Cignal Reporter Assay procedure.
7
Cignal Reporter Assay principle.
Performance
Principle

Cignal Reporter Assays consist of multiple repeats of a specific transcription factor’s binding site and basic promoter elements to drive the expression of a reporter gene (firefly luciferase or GFP). These reporters are powerful tools in functional genomics and drug discovery for assessing pathway activity. When the pathway is activated or inhibited by a drug candidate, gene knockdown, overexpression, or peptide, luciferase or GFP reporter activity is modulated and can be measured quantitatively and rapidly (see figure "Cignal Reporter Assay principle"). The Cignal Reporter Assays are available as transfection-ready constructs utilizing two reporter systems: the dual-luciferase reporter or the GFP reporter (see flowchart "Cignal Reporter Assay procedure").

The dual-luciferase format is an end-point assay providing unsurpassed sensitivity, specificity, and signal-to-noise ratios. This format is available for all Cignal Reporter Assays. Each assay includes a pathway-focused transcription factor reporter and a noninducible negative control, as well as luciferase and GFP positive controls.

The GFP format is an outstanding method for monitoring live cell pathway regulation, with single cell resolution. It includes a pathway-focused transcription factor reporter and positive and negative controls.

Procedure

Cignal Reporter Assays include a preformulated, transfection-ready pathway reporter (dual-luciferase or GFP), plus a positive and negative control. The inducible pathway reporter and noninducible negative control are transfected and subjected to experimental treatments in parallel.

Dual-luciferase

Dual-luciferase results are calculated for each transfectant. The change in the activity of each signaling pathway is determined by comparing the normalized luciferase activities of the reporter in treated versus untreated transfectants. The identically treated negative control transfectants serve as a specificity control. The positive control serves as a control for transfection efficiency, by monitoring firefly luciferase and Renilla expression.

GFP

GFP expression is quantified using a flow cytometer, fluorescence microscope, or fluorometer. The change in the activity of each signaling pathway is determined by comparing the GFP activities in treated versus untreated transfectants. The identically treated negative control transfectants serve as a specificity control. The positive control serves as a control for transfection efficiency, by monitoring GFP expression from the constitutively expressing CMV-GFP reporter.

Applications

Cignal Reporter Assays are powerful tools in functional genomics, proteomics, and drug discovery for assessing the biological impact of pathway inhibition or activation with siRNAs, proteins, and small molecule compounds.

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Brochures & Guides (1)
For cell-based analysis of pathway signaling activity
Show details
Kit Handbooks (1)
Transfection Protocols (2)
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Transfection protocols for specific cell types and plate formats that save you the time and effort of adapting existing protocols to fit your requirements. Simply select the cell type, nucleic acid, and culture format to receive a QIAGEN transfection protocol to print out or download in convenient PDF format.
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ISRE Reporter Assay Kit Cignal Reporter Assay Kits
Introduction
The Cignal ISRE Reporter Assay Kit is designed to monitor the activity of interferon-induced signal transduction pathways in cultured cells. Type I interferons (IFN-α and -β) mediate signaling through STAT1 and STAT2 components of the JAK/STAT-signal transduction pathways. The Interferon Stimulated Response Element (ISRE) reporter is designed for measuring the induction of the STAT1 and STAT2 components of the JAK/STAT-signal transduction pathways. The ISRE reporter is a mixture of an inducible STAT1/STAT2-responsive luciferase construct and a constitutively expressing Renilla construct (40:1). The STAT1/STAT2-responsive luciferase element encodes the firefly luciferase reporter gene under the control of a minimal (m)CMV promoter and tandem repeats of the ISRE. We have experimentally optimized the number of response elements as well as the intervening sequence between response elements to maximize the signal to noise ratio. The constitutively expressing Renilla construct encodes the Renilla luciferase reporter gene under the control of a CMV immediately early enhancer/promoter and acts as an internal control for normalizing transfection efficiencies and monitoring cell viability. Using a simple dual-luciferase assay, you can easily monitor the activity of interferon-induced signal transduction pathways and determine the effect of various treatments, such as gene knockdown, over-expression, and chemical compounds on those pathways.
CCS-008L

The Cignal ISRE Reporter Assay shows a specific response to IFN-α. HeLa cells were transfected with the Cignal ISRE Reporter, negative control, and positive control (for the transfection protocol, refer to the Cignal Reporter Assay Handbook). After 16 hours of transfection, medium was changed to assay medium (Opti-MEM + 10% heat-inactivated FBS + 0.1 mM NEAA + 1 mM sodium pyruvate + 100 U/ml penicillin + 100 µg/ml streptomycin). After 24 hours of transfection, cells were treated with 1000 U/ml IFN-α for 18 hours. A dual-luciferase assay was performed, and promoter activity values are expressed as arbitrary units using a Renilla reporter for internal normalization. Experiments were performed in triplicate, and the standard deviation is indicated.
Name Cignal ISRE Reporter Assay Kit (LUC) (CCS-008L)
Official symbol IFNG [Human]
Official name interferon, gamma
Species Human (Homo sapiens)
Entrez Gene ID 3458
Transcript(s) for this gene NM_000619 (1240 bp), ENST00000229135
Official symbol Ifng [Mouse]
Official name interferon gamma
Species Mouse (Mus musculus)
Entrez Gene ID 15978
Transcript(s) for this gene K00083 (1192 bp), NM_008337 (1210 bp), XM_125899 (1207 bp)
Official symbol Ifng [Rat]
Official name interferon gamma
Species Rat (Rattus norvegicus)
Entrez Gene ID 25712
Transcript(s) for this gene NM_138880 (525 bp)
Official symbol IFNA4 [Human]
Official name interferon, alpha 4
Species Human (Homo sapiens)
Entrez Gene ID 3441
Transcript(s) for this gene NM_021068 (982 bp), ENST00000421715
Official symbol Ifna13 [Mouse]
Official name interferon alpha 13
Species Mouse (Mus musculus)
Entrez Gene ID 230396
Transcript(s) for this gene NM_177347 (819 bp)
Official symbol Ifna1 [Mouse]
Official name interferon alpha 1
Species Mouse (Mus musculus)
Entrez Gene ID 15962
Transcript(s) for this gene NM_010502 (570 bp)
Official symbol Ifna4 [Mouse]
Official name interferon alpha 4
Species Mouse (Mus musculus)
Entrez Gene ID 15967
Transcript(s) for this gene NM_010504 (644 bp)
Official symbol Ifna7 [Mouse]
Official name interferon alpha 7
Species Mouse (Mus musculus)
Entrez Gene ID 15970
Transcript(s) for this gene NM_008334 (576 bp), XM_003946134 (573 bp)
Official symbol Ifna5 [Mouse]
Official name interferon alpha 5
Species Mouse (Mus musculus)
Entrez Gene ID 15968
Transcript(s) for this gene NM_010505 (570 bp)
Official symbol Ifna2 [Mouse]
Official name interferon alpha 2
Species Mouse (Mus musculus)
Entrez Gene ID 15965
Transcript(s) for this gene NM_010503 (573 bp)
Official symbol Ifna6 [Mouse]
Official name interferon alpha 6
Species Mouse (Mus musculus)
Entrez Gene ID 15969
Transcript(s) for this gene NM_008335 (951 bp), NM_206871 (570 bp)
Official symbol Ifna14 [Mouse]
Official name interferon alpha 14
Species Mouse (Mus musculus)
Entrez Gene ID 404549
Transcript(s) for this gene NM_206975 (570 bp)
Official symbol Ifna1 [Rat]
Official name interferon-alpha 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 298210
Transcript(s) for this gene NM_001014786 (579 bp), XM_001052991 (579 bp), XM_216443 (579 bp)
Official symbol Ifna2 [Rat]
Official name interferon alpha 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 298213
Transcript(s) for this gene XM_233152 (579 bp), NM_001271218 (579 bp)
Official symbol Ifna4 [Rat]
Official name interferon, alpha 4
Species Rat (Rattus norvegicus)
Entrez Gene ID 298205
Transcript(s) for this gene NM_001106667 (570 bp), XM_001053305 (570 bp), XM_233145 (570 bp)
Official symbol IRF9 [Human]
Official name interferon regulatory factor 9
Species Human (Homo sapiens)
Entrez Gene ID 10379
Transcript(s) for this gene NM_006084 (1699 bp), ENST00000561415, ENST00000396864, ENST00000557894
Official symbol Irf9 [Mouse]
Official name interferon regulatory factor 9
Species Mouse (Mus musculus)
Entrez Gene ID 16391
Transcript(s) for this gene NM_001159417 (2545 bp), NM_001159418 (2343 bp), NM_008394 (2459 bp), XM_975638 (1408 bp), ENSMUST00000145680
Official symbol Irf9 [Rat]
Official name interferon regulatory factor 9
Species Rat (Rattus norvegicus)
Entrez Gene ID 305896
Transcript(s) for this gene NM_001012041 (1630 bp), XM_224190 (1717 bp), XM_006251974 (2569 bp), XM_006251975 (2513 bp), XM_008770679 (2554 bp)
Official symbol CISH [Human]
Official name cytokine inducible SH2-containing protein
Species Human (Homo sapiens)
Entrez Gene ID 1154
Transcript(s) for this gene NM_013324 (2285 bp), NM_145071 (2128 bp), ENST00000491847, XM_005264846 (3139 bp), ENST00000348721, ENST00000443053
Official symbol Cish [Mouse]
Official name cytokine inducible SH2-containing protein
Species Mouse (Mus musculus)
Entrez Gene ID 12700
Transcript(s) for this gene NM_009895 (3014 bp), ENSMUST00000165664, XM_006511635 (3090 bp), NM_001317354 (2793 bp), XM_011242853 (1945 bp), XM_011242854 (1938 bp)
Official symbol Cish [Rat]
Official name cytokine inducible SH2-containing protein
Species Rat (Rattus norvegicus)
Entrez Gene ID 83681
Transcript(s) for this gene NM_031804 (1879 bp), XM_001074104 (1352 bp), XM_343472 (1352 bp)
Official symbol JUNB [Human]
Official name jun B proto-oncogene
Species Human (Homo sapiens)
Entrez Gene ID 3726
Transcript(s) for this gene NM_002229 (1832 bp), ENST00000302754
Official symbol Junb [Mouse]
Official name jun B proto-oncogene
Species Mouse (Mus musculus)
Entrez Gene ID 16477
Transcript(s) for this gene NM_008416 (1840 bp)
Official symbol Junb [Rat]
Official name jun B proto-oncogene
Species Rat (Rattus norvegicus)
Entrez Gene ID 24517
Transcript(s) for this gene NM_021836 (1822 bp)
Official symbol FOS [Human]
Official name FBJ murine osteosarcoma viral oncogene homolog
Species Human (Homo sapiens)
Entrez Gene ID 2353
Transcript(s) for this gene NM_005252 (2158 bp), ENST00000556324, ENST00000303562, ENST00000535987, ENST00000554617, ENST00000555242, ENST00000555347, ENST00000555686
Official symbol Fos [Mouse]
Official name FBJ osteosarcoma oncogene
Species Mouse (Mus musculus)
Entrez Gene ID 14281
Transcript(s) for this gene NM_010234 (2107 bp), ENSMUST00000140525
Official symbol Fos [Rat]
Official name FBJ osteosarcoma oncogene
Species Rat (Rattus norvegicus)
Entrez Gene ID 314322
Transcript(s) for this gene NM_022197 (1589 bp), XM_234422 (1713 bp)
Official symbol IFNA1 [Human]
Official name interferon, alpha 1
Species Human (Homo sapiens)
Entrez Gene ID 3439
Transcript(s) for this gene NM_024013 (863 bp), ENST00000276927, ENST00000613815
Official symbol IFNA5 [Human]
Official name interferon, alpha 5
Species Human (Homo sapiens)
Entrez Gene ID 3442
Transcript(s) for this gene NM_002169 (700 bp), ENST00000610521
Official symbol IFNA16 [Human]
Official name interferon, alpha 16
Species Human (Homo sapiens)
Entrez Gene ID 3449
Transcript(s) for this gene NM_002173 (939 bp), ENST00000380216
Official symbol GBP1 [Human]
Official name guanylate binding protein 1, interferon-inducible
Species Human (Homo sapiens)
Entrez Gene ID 2633
Transcript(s) for this gene NM_002053 (3050 bp), ENST00000495131, XM_006710573 (2501 bp), ENST00000370473
Official symbol Gbp1 [Rat]
Official name guanylate binding protein 1, interferon-inducible
Species Rat (Rattus norvegicus)
Entrez Gene ID 304266
Transcript(s) for this gene XM_001078913 (2517 bp), XM_221882 (2517 bp), XM_006224278 (3276 bp), XM_006233425 (3263 bp), XM_008761538 (3458 bp)
Official symbol IFNA8 [Human]
Official name interferon, alpha 8
Species Human (Homo sapiens)
Entrez Gene ID 3445
Transcript(s) for this gene NM_002170 (1039 bp), ENST00000380205
Official symbol TYK2 [Human]
Official name tyrosine kinase 2
Species Human (Homo sapiens)
Entrez Gene ID 7297
Transcript(s) for this gene NM_003331 (4262 bp), ENST00000592137, ENST00000264818, ENST00000524462, ENST00000525621, ENST00000529370
Official symbol Tyk2 [Mouse]
Official name tyrosine kinase 2
Species Mouse (Mus musculus)
Entrez Gene ID 54721
Transcript(s) for this gene NM_001205312 (4873 bp), NM_018793 (4822 bp), XM_006510492 (4484 bp), XM_006510493 (4151 bp), XM_006510494 (2608 bp), XM_006510495 (2325 bp), XM_011242579 (4764 bp)
Official symbol CXCL9 [Human]
Official name chemokine (C-X-C motif) ligand 9
Species Human (Homo sapiens)
Entrez Gene ID 4283
Transcript(s) for this gene NM_002416 (2723 bp), ENST00000264888
Official symbol Cxcl9 [Mouse]
Official name chemokine (C-X-C motif) ligand 9
Species Mouse (Mus musculus)
Entrez Gene ID 17329
Transcript(s) for this gene NM_008599 (2905 bp)
Official symbol Cxcl9 [Rat]
Official name chemokine (C-X-C motif) ligand 9
Species Rat (Rattus norvegicus)
Entrez Gene ID 246759
Transcript(s) for this gene NM_145672 (554 bp)
Official symbol HSPA4 [Human]
Official name heat shock 70kDa protein 4
Species Human (Homo sapiens)
Entrez Gene ID 3308
Transcript(s) for this gene NM_002154 (3385 bp), NM_198431 (1309 bp), ENST00000514825, ENST00000304858, ENST00000615899, ENST00000617074, ENST00000617819
Official symbol Hspa4 [Mouse]
Official name heat shock protein 4
Species Mouse (Mus musculus)
Entrez Gene ID 15525
Transcript(s) for this gene NM_008300 (4657 bp), ENSMUST00000151854
Official symbol Hspa4 [Rat]
Official name heat shock protein 4
Species Rat (Rattus norvegicus)
Entrez Gene ID 266759
Transcript(s) for this gene NM_153629 (4521 bp), XM_006246232 (4561 bp)
Official symbol IFNB1 [Human]
Official name interferon, beta 1, fibroblast
Species Human (Homo sapiens)
Entrez Gene ID 3456
Transcript(s) for this gene NM_002176 (840 bp), ENST00000380232
Official symbol Ifnb1 [Mouse]
Official name interferon beta 1, fibroblast
Species Mouse (Mus musculus)
Entrez Gene ID 15977
Transcript(s) for this gene NM_010510 (770 bp)
Official symbol Ifnb1 [Rat]
Official name interferon beta 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24481
Transcript(s) for this gene NM_019127 (555 bp)
Official symbol IFNA14 [Human]
Official name interferon, alpha 14
Species Human (Homo sapiens)
Entrez Gene ID 3448
Transcript(s) for this gene NM_002172 (778 bp), ENST00000380222
Official symbol IFNA21 [Human]
Official name interferon, alpha 21
Species Human (Homo sapiens)
Entrez Gene ID 3452
Transcript(s) for this gene NM_002175 (1024 bp), ENST00000380225
Official symbol CD36 [Human]
Official name CD36 molecule (thrombospondin receptor)
Species Human (Homo sapiens)
Entrez Gene ID 948
Transcript(s) for this gene NM_000072 (2108 bp), NM_001001547 (2069 bp), NM_001001548 (4727 bp), NM_001127443 (1814 bp), NM_001127444 (1989 bp), ENST00000526804, NM_001289908 (1665 bp), NM_001289909 (1693 bp), NM_001289911 (1747 bp), XM_005250713 (4666 bp), XM_005250714 (4633 bp), XM_005250715 (4975 bp), ENST00000309881, ENST00000394788, ENST00000432207, ENST00000433696, ENST00000435819, ENST00000447544, ENST00000534394, ENST00000538969, ENST00000544133
Official symbol Cd36 [Mouse]
Official name CD36 antigen
Species Mouse (Mus musculus)
Entrez Gene ID 12491
Transcript(s) for this gene NM_001159555 (3539 bp), NM_001159556 (3399 bp), NM_001159557 (3450 bp), NM_001159558 (3566 bp), NM_007643 (3542 bp), XM_006535620 (2712 bp), XM_006535621 (2770 bp), XM_006535622 (2713 bp), XM_006535623 (2709 bp), XM_006535624 (2763 bp), XM_006535625 (2617 bp)
Official symbol Cd36 [Rat]
Official name CD36 molecule (thrombospondin receptor)
Species Rat (Rattus norvegicus)
Entrez Gene ID 29184
Transcript(s) for this gene NM_031561 (2625 bp)
Official symbol CIITA [Human]
Official name class II, major histocompatibility complex, transactivator
Species Human (Homo sapiens)
Entrez Gene ID 4261
Transcript(s) for this gene NM_000246 (4654 bp), ENST00000575513, NM_001286402 (4657 bp), NM_001286403 (2902 bp), XM_005255320 (4823 bp), XM_005255321 (4820 bp), XM_005255323 (4385 bp), XM_006720880 (4870 bp), XM_006720881 (4676 bp), XM_006720882 (4673 bp), XM_006720883 (4376 bp), ENST00000324288, ENST00000381835, ENST00000611587, ENST00000618207, ENST00000618327
Official symbol Ciita [Mouse]
Official name class II transactivator
Species Mouse (Mus musculus)
Entrez Gene ID 12265
Transcript(s) for this gene NM_001243760 (5435 bp), NM_001243761 (5167 bp), NM_007575 (5330 bp), XR_105754 (5091 bp), XR_106998 (5091 bp), NM_001302618 (5438 bp), NM_001302619 (5666 bp), XM_006521723 (4370 bp), XM_006521724 (3378 bp), XM_006521725 (6933 bp), XM_006521726 (3934 bp), XM_006521727 (3826 bp), XM_006521728 (3041 bp), XM_011245810 (6475 bp)
Official symbol Ciita [Rat]
Official name class II, major histocompatibility complex, transactivator
Species Rat (Rattus norvegicus)
Entrez Gene ID 85483
Transcript(s) for this gene NM_053529 (5295 bp), NM_001270803 (5076 bp), NM_001270804 (5004 bp), XM_006245738 (5624 bp), XM_008767501 (6620 bp)
Official symbol EIF2AK2 [Human]
Official name eukaryotic translation initiation factor 2-alpha kinase 2
Species Human (Homo sapiens)
Entrez Gene ID 5610
Transcript(s) for this gene NM_001135651 (4127 bp), NM_001135652 (3697 bp), NM_002759 (4361 bp), ENST00000496059, ENST00000233057, ENST00000395127, ENST00000405334
Official symbol Eif2ak2 [Mouse]
Official name eukaryotic translation initiation factor 2-alpha kinase 2
Species Mouse (Mus musculus)
Entrez Gene ID 19106
Transcript(s) for this gene NM_011163 (4343 bp), ENSMUST00000171852, XM_006523863 (2279 bp)
Official symbol Gbp2b [Mouse]
Official name guanylate binding protein 2b
Species Mouse (Mus musculus)
Entrez Gene ID 14468
Transcript(s) for this gene NM_010259 (2820 bp), XM_001004411 (537 bp), XM_006500999 (2856 bp), XM_011240014 (1804 bp), XM_011240015 (2652 bp), XM_011240016 (1499 bp)
Official symbol Cxcl10 [Mouse]
Official name chemokine (C-X-C motif) ligand 10
Species Mouse (Mus musculus)
Entrez Gene ID 15945
Transcript(s) for this gene NM_021274 (1120 bp), XM_975312 (344 bp), XM_975346 (679 bp), XM_975377 (1099 bp), ENSMUST00000138169
Official symbol CXCL10 [Human]
Official name chemokine (C-X-C motif) ligand 10
Species Human (Homo sapiens)
Entrez Gene ID 3627
Transcript(s) for this gene NM_001565 (1227 bp), ENST00000306602
Official symbol Cxcl10 [Rat]
Official name chemokine (C-X-C motif) ligand 10
Species Rat (Rattus norvegicus)
Entrez Gene ID 245920
Transcript(s) for this gene NM_139089 (1133 bp)
Official symbol Nos2 [Mouse]
Official name nitric oxide synthase 2, inducible
Species Mouse (Mus musculus)
Entrez Gene ID 18126
Transcript(s) for this gene NM_010927 (4164 bp), XM_001001508 (3090 bp), XM_006532446 (4018 bp), NM_001313921 (3915 bp), NM_001313922 (3815 bp)
Official symbol NOS2 [Human]
Official name nitric oxide synthase 2, inducible
Species Human (Homo sapiens)
Entrez Gene ID 4843
Transcript(s) for this gene NM_000625 (4206 bp), NM_153292 (4104 bp), ENST00000313735, ENST00000621962
Official symbol Nos2 [Rat]
Official name nitric oxide synthase 2, inducible
Species Rat (Rattus norvegicus)
Entrez Gene ID 24599
Transcript(s) for this gene NM_012611 (3793 bp)
Official symbol Socs3 [Mouse]
Official name suppressor of cytokine signaling 3
Species Mouse (Mus musculus)
Entrez Gene ID 12702
Transcript(s) for this gene NM_007707 (2742 bp), ENSMUST00000132295, XM_006532110 (3610 bp), XM_011248707 (2927 bp)
Official symbol SOCS3 [Human]
Official name suppressor of cytokine signaling 3
Species Human (Homo sapiens)
Entrez Gene ID 9021
Transcript(s) for this gene NM_003955 (2737 bp), ENST00000330871
Official symbol Socs3 [Rat]
Official name suppressor of cytokine signaling 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 89829
Transcript(s) for this gene NM_053565 (863 bp), XM_008768398 (2546 bp)
Official symbol Ifnar2 [Mouse]
Official name interferon (alpha and beta) receptor 2
Species Mouse (Mus musculus)
Entrez Gene ID 15976
Transcript(s) for this gene NM_001110498 (1169 bp), NM_010509 (3051 bp), XM_006522923 (3461 bp), XM_011246100 (3491 bp)
Official symbol IFNAR2 [Human]
Official name interferon (alpha, beta and omega) receptor 2
Species Human (Homo sapiens)
Entrez Gene ID 3455
Transcript(s) for this gene NM_000874 (1459 bp), NM_207584 (1413 bp), NM_207585 (2920 bp), ENST00000420068, NM_001289125 (2966 bp), NM_001289126 (2789 bp), NM_001289128 (2835 bp), ENST00000342101, ENST00000342136, ENST00000382264, ENST00000404220, ENST00000413881
Official symbol Klf4 [Mouse]
Official name Kruppel-like factor 4 (gut)
Species Mouse (Mus musculus)
Entrez Gene ID 16600
Transcript(s) for this gene NM_010637 (3057 bp)
Official symbol KLF4 [Human]
Official name Kruppel-like factor 4 (gut)
Species Human (Homo sapiens)
Entrez Gene ID 9314
Transcript(s) for this gene NM_004235 (2949 bp), ENST00000497048, XM_005252305 (2832 bp), ENST00000374672, ENST00000610832
Official symbol Klf4 [Rat]
Official name Kruppel-like factor 4 (gut)
Species Rat (Rattus norvegicus)
Entrez Gene ID 114505
Transcript(s) for this gene NM_053713 (2393 bp)
Official symbol Ifnar1 [Mouse]
Official name interferon (alpha and beta) receptor 1
Species Mouse (Mus musculus)
Entrez Gene ID 15975
Transcript(s) for this gene NM_010508 (7025 bp), ENSMUST00000145008, XR_384931 (3531 bp)
Official symbol IFNAR1 [Human]
Official name interferon (alpha, beta and omega) receptor 1
Species Human (Homo sapiens)
Entrez Gene ID 3454
Transcript(s) for this gene NM_000629 (6099 bp), ENST00000493503, XM_005260964 (6064 bp), ENST00000270139
Official symbol Ifnar1 [Rat]
Official name interferon alpha and beta receptor subunit 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 288264
Transcript(s) for this gene NM_001105893 (3903 bp), XM_001073651 (5301 bp), XM_213649 (5317 bp), NM_001271316 (4093 bp)
Official symbol Bace1 [Mouse]
Official name beta-site APP cleaving enzyme 1
Species Mouse (Mus musculus)
Entrez Gene ID 23821
Transcript(s) for this gene NM_001145947 (4092 bp), NM_011792 (4194 bp), ENSMUST00000162559
Official symbol BACE1 [Human]
Official name beta-site APP-cleaving enzyme 1
Species Human (Homo sapiens)
Entrez Gene ID 23621
Transcript(s) for this gene NM_001207048 (5226 bp), NM_001207049 (5151 bp), NM_012104 (5864 bp), NM_138971 (5732 bp), NM_138972 (5789 bp), NM_138973 (5657 bp), ENST00000530824, ENST00000313005, ENST00000392937, ENST00000428381, ENST00000445823, ENST00000510630, ENST00000513780, ENST00000528053
Official symbol Bace1 [Rat]
Official name beta-site APP cleaving enzyme 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 29392
Transcript(s) for this gene NM_019204 (2158 bp)
Official symbol OAS1 [Human]
Official name 2'-5'-oligoadenylate synthetase 1, 40/46kDa
Species Human (Homo sapiens)
Entrez Gene ID 4938
Transcript(s) for this gene NM_001032409 (1575 bp), NM_002534 (1470 bp), NM_016816 (1673 bp), ENST00000549820, XM_006719434 (2435 bp), ENST00000202917, ENST00000445409, ENST00000452357, ENST00000551241, ENST00000553185
Official symbol Oas1a [Mouse]
Official name 2'-5' oligoadenylate synthetase 1A
Species Mouse (Mus musculus)
Entrez Gene ID 246730
Transcript(s) for this gene NM_145211 (1889 bp), XM_994107 (1490 bp), XM_006530330 (1486 bp)
Official symbol Soat1 [Mouse]
Official name sterol O-acyltransferase 1
Species Mouse (Mus musculus)
Entrez Gene ID 20652
Transcript(s) for this gene NM_009230 (4785 bp), XM_006496719 (4612 bp), XM_011238778 (4753 bp)
Official symbol SOAT1 [Human]
Official name sterol O-acyltransferase 1
Species Human (Homo sapiens)
Entrez Gene ID 6646
Transcript(s) for this gene NM_001252511 (6879 bp), NM_001252512 (6812 bp), NM_003101 (6938 bp), NR_045530 (6857 bp), ENST00000367619, ENST00000539888, ENST00000540564, XM_011509911 (7111 bp), XM_011509912 (1305 bp)
Official symbol Soat1 [Rat]
Official name sterol O-acyltransferase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 81782
Transcript(s) for this gene NM_031118 (1750 bp), XM_008769681 (4635 bp)
Official symbol Ddb1 [Rat]
Official name damage-specific DNA binding protein 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 64470
Transcript(s) for this gene NM_171995 (4260 bp), XM_002725785 (4249 bp), XM_002728866 (4249 bp), XM_342024 (4242 bp), XM_006231071 (4281 bp)
Official symbol DDB1 [Human]
Official name damage-specific DNA binding protein 1, 127kDa
Species Human (Homo sapiens)
Entrez Gene ID 1642
Transcript(s) for this gene NM_001923 (4372 bp), XM_001128974 (5167 bp), XM_001128983 (5389 bp), ENST00000545930, ENST00000301764
Official symbol Ddb1 [Mouse]
Official name damage specific DNA binding protein 1
Species Mouse (Mus musculus)
Entrez Gene ID 13194
Transcript(s) for this gene NM_015735 (4171 bp), XM_006526639 (4257 bp)
Official symbol Nfkb1 [Rat]
Official name nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 81736
Transcript(s) for this gene XM_001075876 (3723 bp), XM_342346 (4088 bp), NM_001276711 (3956 bp), XM_006233358 (3612 bp), XM_006233360 (3434 bp)
Official symbol NFKB1 [Human]
Official name nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Species Human (Homo sapiens)
Entrez Gene ID 4790
Transcript(s) for this gene NM_001165412 (4090 bp), NM_003998 (4093 bp), ENST00000513803, XM_005263029 (4007 bp), XM_006714229 (3642 bp), ENST00000226574, ENST00000394820, ENST00000505458, ENST00000600343
Official symbol Nfkb1 [Mouse]
Official name nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Species Mouse (Mus musculus)
Entrez Gene ID 18033
Transcript(s) for this gene NM_008689 (4128 bp), ENSMUST00000150007, XM_006501105 (3394 bp), XM_006501106 (3618 bp), XM_006501107 (3808 bp)
Official symbol Eif2ak2 [Rat]
Official name eukaryotic translation initiation factor 2-alpha kinase 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 54287
Transcript(s) for this gene NM_019335 (3808 bp), XM_579433 (1554 bp), XM_008764425 (4032 bp), XM_008764426 (3874 bp)
Official symbol Isg15 [Rat]
Official name ISG15 ubiquitin-like modifier
Species Rat (Rattus norvegicus)
Entrez Gene ID 298693
Transcript(s) for this gene NM_001106700 (663 bp), XM_001077878 (703 bp), XM_216605 (703 bp), XM_006239563 (1297 bp)
Official symbol Prdx2 [Rat]
Official name peroxiredoxin 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 29338
Transcript(s) for this gene NM_017169 (877 bp), XM_006255244 (1059 bp)
Official symbol PRDX2 [Human]
Official name peroxiredoxin 2
Species Human (Homo sapiens)
Entrez Gene ID 7001
Transcript(s) for this gene NM_005809 (1052 bp), NM_181737 (886 bp), NM_181738 (710 bp), ENST00000498785, ENST00000301522, ENST00000334482
Official symbol Prdx2 [Mouse]
Official name peroxiredoxin 2
Species Mouse (Mus musculus)
Entrez Gene ID 21672
Transcript(s) for this gene NM_011563 (1481 bp), ENSMUST00000143402, XM_006530835 (1021 bp), NM_001317385 (1446 bp)
Official symbol Irf1 [Rat]
Official name interferon regulatory factor 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 24508
Transcript(s) for this gene NM_012591 (2078 bp)
Official symbol IRF1 [Human]
Official name interferon regulatory factor 1
Species Human (Homo sapiens)
Entrez Gene ID 3659
Transcript(s) for this gene NM_002198 (3567 bp), ENST00000493208, ENST00000472045, ENST00000245414, ENST00000405885, ENST00000613424
Official symbol Irf1 [Mouse]
Official name interferon regulatory factor 1
Species Mouse (Mus musculus)
Entrez Gene ID 16362
Transcript(s) for this gene NM_001159393 (2128 bp), NM_001159396 (2106 bp), NM_008390 (2151 bp), ENSMUST00000153054, XM_006532308 (2219 bp)
Official symbol Jak3 [Rat]
Official name Janus kinase 3
Species Rat (Rattus norvegicus)
Entrez Gene ID 25326
Transcript(s) for this gene NM_012855 (3793 bp), XM_008771064 (4891 bp)
Official symbol JAK3 [Human]
Official name Janus kinase 3
Species Human (Homo sapiens)
Entrez Gene ID 3718
Transcript(s) for this gene NM_000215 (5449 bp), ENST00000528705, XM_005259896 (5475 bp), XM_006722745 (3795 bp), ENST00000458235, ENST00000527670, ENST00000534444
Official symbol Jak3 [Mouse]
Official name Janus kinase 3
Species Mouse (Mus musculus)
Entrez Gene ID 16453
Transcript(s) for this gene NM_001190830 (3679 bp), NM_010589 (3950 bp), ENSMUST00000133263
Official symbol Ccl2 [Rat]
Official name C-C motif chemokine ligand 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 24770
Transcript(s) for this gene NM_031530 (780 bp)
Official symbol CCL2 [Human]
Official name chemokine (C-C motif) ligand 2
Species Human (Homo sapiens)
Entrez Gene ID 6347
Transcript(s) for this gene NM_002982 (760 bp), ENST00000582017, ENST00000225831, ENST00000580907
Official symbol Ccl2 [Mouse]
Official name chemokine (C-C motif) ligand 2
Species Mouse (Mus musculus)
Entrez Gene ID 20296
Transcript(s) for this gene NM_011333 (806 bp), ENSMUST00000124479
Official symbol Stat1 [Rat]
Official name signal transducer and activator of transcription 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 25124
Transcript(s) for this gene NM_001034164 (2772 bp), NM_032612 (4102 bp)
Official symbol STAT1 [Human]
Official name signal transducer and activator of transcription 1, 91kDa
Species Human (Homo sapiens)
Entrez Gene ID 6772
Transcript(s) for this gene NM_007315 (4326 bp), NM_139266 (2798 bp), ENST00000464072, XM_006712718 (3988 bp), ENST00000361099, ENST00000392322, ENST00000392323, ENST00000409465, ENST00000540176
Official symbol Stat1 [Mouse]
Official name signal transducer and activator of transcription 1
Species Mouse (Mus musculus)
Entrez Gene ID 20846
Transcript(s) for this gene NM_001205313 (5150 bp), NM_001205314 (5168 bp), NM_009283 (5183 bp), XM_006495811 (4186 bp), XM_006495812 (4183 bp), XM_006495813 (4175 bp)
Official symbol ISG15 [Human]
Official name ISG15 ubiquitin-like modifier
Species Human (Homo sapiens)
Entrez Gene ID 9636
Transcript(s) for this gene NM_005101 (685 bp), ENST00000379389, ENST00000624697
Official symbol Isg15 [Mouse]
Official name ISG15 ubiquitin-like modifier
Species Mouse (Mus musculus)
Entrez Gene ID 100038882
Transcript(s) for this gene NM_015783 (756 bp), XM_001471686 (706 bp)
Official symbol CASP8 [Human]
Official name caspase 8, apoptosis-related cysteine peptidase
Species Human (Homo sapiens)
Entrez Gene ID 841
Transcript(s) for this gene NM_001080124 (2750 bp), NM_001080125 (2938 bp), NM_001228 (2914 bp), NM_033355 (2769 bp), NM_033356 (2655 bp), NM_033357 (3044 bp), NM_033358 (1123 bp), ENST00000490682, XM_005246885 (2710 bp), XM_005246886 (2681 bp), XM_005246887 (2833 bp), XM_005246888 (2775 bp), XM_005246889 (2652 bp), XM_005246890 (2650 bp), XM_005246891 (2903 bp), XM_005246892 (2607 bp), XM_005246893 (1020 bp), XM_005246894 (2768 bp), XM_005246895 (975 bp), XM_005246896 (1295 bp), XM_006712789 (2792 bp), XM_006712790 (2675 bp), XM_006712791 (2503 bp), XM_006712792 (1003 bp), XM_006712793 (1098 bp), XR_241323 (2051 bp), ENST00000264274, ENST00000264275, ENST00000323492, ENST00000358485, ENST00000392258, ENST00000392266, ENST00000432109
Official symbol Casp8 [Mouse]
Official name caspase 8
Species Mouse (Mus musculus)
Entrez Gene ID 12370
Transcript(s) for this gene AF067834 (1975 bp), NM_001080126 (2412 bp), NM_009812 (2585 bp), NM_001277926 (2528 bp), XM_006495634 (2351 bp)
Official symbol Casp8 [Rat]
Official name caspase 8
Species Rat (Rattus norvegicus)
Entrez Gene ID 64044
Transcript(s) for this gene NM_022277 (2003 bp), XM_006245014 (2503 bp), XM_006245015 (2644 bp), XM_008767135 (2446 bp)
Official symbol Tbx21 [Mouse]
Official name T-box 21
Species Mouse (Mus musculus)
Entrez Gene ID 57765
Transcript(s) for this gene NM_019507 (2552 bp), XM_977626 (2367 bp)
Official symbol TBX21 [Human]
Official name T-box 21
Species Human (Homo sapiens)
Entrez Gene ID 30009
Transcript(s) for this gene NM_013351 (2589 bp), ENST00000581328, ENST00000177694
Official symbol Tbx21 [Rat]
Official name T-box 21
Species Rat (Rattus norvegicus)
Entrez Gene ID 303496
Transcript(s) for this gene NM_001107043 (2428 bp), XM_001081363 (2479 bp), XM_220914 (2479 bp)
Official symbol Cd40 [Mouse]
Official name CD40 antigen
Species Mouse (Mus musculus)
Entrez Gene ID 21939
Transcript(s) for this gene NM_011611 (1683 bp), NM_170701 (1784 bp), NM_170702 (1596 bp), NM_170703 (1621 bp), NM_170704 (1678 bp), NR_027852 (1784 bp), XM_006499153 (1668 bp), XM_006499154 (1640 bp), XM_006499155 (1789 bp)
Official symbol CD40 [Human]
Official name CD40 molecule, TNF receptor superfamily member 5
Species Human (Homo sapiens)
Entrez Gene ID 958
Transcript(s) for this gene NM_001250 (1629 bp), NM_152854 (1567 bp), ENST00000489304, NM_001302753 (1669 bp), XM_005260617 (1533 bp), XM_005260619 (1372 bp), XM_006723889 (1446 bp), XM_005260618 (1434 bp), ENST00000372276, ENST00000372285, ENST00000620709
Official symbol Cd40 [Rat]
Official name CD40 molecule, TNF receptor superfamily member 5
Species Rat (Rattus norvegicus)
Entrez Gene ID 171369
Transcript(s) for this gene NM_134360 (1272 bp), XM_006235511 (1631 bp), XM_008762463 (1303 bp), XM_008762464 (1303 bp), XM_008762465 (1247 bp)
Official symbol Ep300 [Mouse]
Official name E1A binding protein p300
Species Mouse (Mus musculus)
Entrez Gene ID 328572
Transcript(s) for this gene NM_177821 (8749 bp), XM_006521089 (8768 bp), XM_006521090 (8747 bp), XM_006521091 (8241 bp)
Official symbol EP300 [Human]
Official name E1A binding protein p300
Species Human (Homo sapiens)
Entrez Gene ID 2033
Transcript(s) for this gene NM_001429 (8761 bp), XM_006724165 (8997 bp), ENST00000263253
Official symbol Ep300 [Rat]
Official name E1A binding protein p300
Species Rat (Rattus norvegicus)
Entrez Gene ID 170915
Transcript(s) for this gene XM_001076610 (9293 bp), XM_576312 (8309 bp), XM_006226166 (9272 bp), XM_008765878 (9260 bp)
Official symbol Jak2 [Mouse]
Official name Janus kinase 2
Species Mouse (Mus musculus)
Entrez Gene ID 16452
Transcript(s) for this gene NM_001048177 (4972 bp), NM_008413 (5055 bp), XM_006526713 (4922 bp), XM_006526714 (4369 bp), XM_006526715 (4554 bp), XM_011247155 (4734 bp)
Official symbol JAK2 [Human]
Official name Janus kinase 2
Species Human (Homo sapiens)
Entrez Gene ID 3717
Transcript(s) for this gene NM_004972 (5285 bp), ENST00000487310, XM_005251455 (6669 bp), ENST00000381652
Official symbol Jak2 [Rat]
Official name Janus kinase 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 24514
Transcript(s) for this gene NM_031514 (3731 bp)
Official symbol Jak1 [Mouse]
Official name Janus kinase 1
Species Mouse (Mus musculus)
Entrez Gene ID 16451
Transcript(s) for this gene NM_146145 (5299 bp), ENSMUST00000155328, ENSMUST00000132292, XM_006502812 (5126 bp), XM_006502813 (5173 bp), XM_011240451 (4911 bp)
Official symbol JAK1 [Human]
Official name Janus kinase 1
Species Human (Homo sapiens)
Entrez Gene ID 3716
Transcript(s) for this gene NM_002227 (5053 bp), ENST00000494904, XM_005270841 (4905 bp), XM_006710624 (4959 bp), ENST00000342505
Official symbol Jak1 [Rat]
Official name Janus kinase 1
Species Rat (Rattus norvegicus)
Entrez Gene ID 84598
Transcript(s) for this gene NM_053466 (4291 bp), XM_001061647 (6114 bp), XM_342872 (6114 bp), XM_006238452 (4904 bp), XM_006238453 (8527 bp)
Official symbol Stat2 [Mouse]
Official name signal transducer and activator of transcription 2
Species Mouse (Mus musculus)
Entrez Gene ID 20847
Transcript(s) for this gene NM_019963 (4402 bp), XM_990913 (4478 bp), XM_006513433 (4423 bp), XM_006513434 (4375 bp), XM_006513435 (4323 bp), XM_006513436 (2200 bp)
Official symbol STAT2 [Human]
Official name signal transducer and activator of transcription 2, 113kDa
Species Human (Homo sapiens)
Entrez Gene ID 6773
Transcript(s) for this gene NM_005419 (4576 bp), NM_198332 (4564 bp), ENST00000557417, ENST00000556140, XM_005269108 (4569 bp), XM_005269109 (4557 bp), XM_005269110 (1684 bp), XM_005269111 (1725 bp), XM_006719572 (2182 bp), ENST00000314128, ENST00000418572, ENST00000557235
Official symbol Stat2 [Rat]
Official name signal transducer and activator of transcription 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 288774
Transcript(s) for this gene NM_001011905 (3464 bp), XM_222301 (2733 bp), XM_006240747 (3759 bp), XM_006240748 (3705 bp)
Official symbol Pml [Mouse]
Official name promyelocytic leukemia
Species Mouse (Mus musculus)
Entrez Gene ID 18854
Transcript(s) for this gene NM_008884 (5240 bp), NM_178087 (5378 bp), ENSMUST00000154572, XM_006510860 (3556 bp), XM_006510861 (3418 bp), XM_006510862 (6332 bp), XM_006510863 (4487 bp), XM_006510864 (4340 bp), NM_001311088 (5373 bp)
Official symbol PML [Human]
Official name promyelocytic leukemia
Species Human (Homo sapiens)
Entrez Gene ID 5371
Transcript(s) for this gene NM_002675 (2254 bp), NM_033238 (5600 bp), NM_033239 (3088 bp), NM_033240 (3751 bp), NM_033242 (3073 bp), NM_033244 (3096 bp), NM_033245 (3736 bp), NM_033246 (1851 bp), NM_033247 (1797 bp), NM_033249 (2110 bp), NM_033250 (2944 bp), XM_001132060 (2013 bp), ENST00000570213, ENST00000268058, ENST00000268059, ENST00000354026, ENST00000359928, ENST00000395132, ENST00000395135, ENST00000435786, ENST00000436891, ENST00000563500, ENST00000564428, ENST00000565898, ENST00000567543, ENST00000569477, ENST00000569965
Official symbol Pml [Rat]
Official name promyelocytic leukemia
Species Rat (Rattus norvegicus)
Entrez Gene ID 315713
Transcript(s) for this gene XM_001074703 (2647 bp), XM_236296 (2647 bp), XM_006226414 (5455 bp), XM_008766431 (5455 bp)
Official symbol Psmb9 [Mouse]
Official name proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
Species Mouse (Mus musculus)
Entrez Gene ID 16912
Transcript(s) for this gene NM_013585 (806 bp), ENSMUST00000179593, ENSMUST00000114230, XM_006523729 (1355 bp), XM_006523730 (980 bp), XM_006525329 (1355 bp), XM_006525330 (980 bp), XM_006536547 (1050 bp), XM_006536548 (1023 bp), XM_006537281 (1050 bp), XM_006537282 (1023 bp)
Official symbol PSMB9 [Human]
Official name proteasome (prosome, macropain) subunit, beta type, 9
Species Human (Homo sapiens)
Entrez Gene ID 5698
Transcript(s) for this gene NM_002800 (1048 bp), NM_148954 (1018 bp), ENST00000467593, ENST00000464863, ENST00000374859, ENST00000395330
Official symbol Psmb9 [Rat]
Official name proteasome (prosome, macropain) subunit, beta type, 9
Species Rat (Rattus norvegicus)
Entrez Gene ID 24967
Transcript(s) for this gene NM_012708 (913 bp)
Official symbol IFNA2 [Human]
Official name interferon, alpha 2
Species Human (Homo sapiens)
Entrez Gene ID 3440
Transcript(s) for this gene NM_000605 (1143 bp), ENST00000380206
Official symbol IFNA10 [Human]
Official name interferon, alpha 10
Species Human (Homo sapiens)
Entrez Gene ID 3446
Transcript(s) for this gene NM_002171 (963 bp), ENST00000357374
Official symbol IFNA13 [Human]
Official name interferon, alpha 13
Species Human (Homo sapiens)
Entrez Gene ID 3447
Transcript(s) for this gene NM_006900 (705 bp), ENST00000449498, ENST00000610660
Official symbol IFNA6 [Human]
Official name interferon, alpha 6
Species Human (Homo sapiens)
Entrez Gene ID 3443
Transcript(s) for this gene NM_021002 (570 bp), ENST00000259555, ENST00000380210
Official symbol IFNA7 [Human]
Official name interferon, alpha 7
Species Human (Homo sapiens)
Entrez Gene ID 3444
Transcript(s) for this gene NM_021057 (737 bp), ENST00000239347
Official symbol IFNA17 [Human]
Official name interferon, alpha 17
Species Human (Homo sapiens)
Entrez Gene ID 3451
Transcript(s) for this gene NM_021268 (980 bp), ENST00000413767, ENST00000619448
Official symbol Tyk2 [Rat]
Official name tyrosine kinase 2
Species Rat (Rattus norvegicus)
Entrez Gene ID 298706
Transcript(s) for this gene XM_233741 (3550 bp)

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