Overview
Solutions for even your most challenging samples
Casework samples – whether from sexual assault cases, kinship testing, disaster victim ID or other scenarios – are difficult to work with. They often contain highly degraded DNA, high inhibitor contents or mixed DNA from multiple individuals. To help forensic labs overcome these challenges, we've developed dedicated products and protocols, including robust instrumentation for sample preparation and a complete analytical assay portfolio, that are optimized for compromised DNA. In addition, QIAGEN scientists and technical support specialists are ready to help you prepare for even the most sensitive and challenging applications.
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Sample collection -
Pretreatment -
Assay setupInstrumentsMethylation analysis
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Quantification -
Human autosomal STR analysisHuman autosomal STR kits
- Investigator 24plex QS and GO! Kits
- Investigator 26plex QS Kit
- Investigator ESSplex SE QS
- Investigator IDplex Plus and GO! Kits
Supplementary human autosomal STR kits
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Other STR and NGS analysis
Human gonosomal STR kits
Human bi-allelic marker kits
NGS library prep
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How can we help support your casework?
Get in touch with our experts to find out how we can help streamline your workflow for challenging samples.
Tailored solutions for challenging applications
Sexual assault samples
Missing persons
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An NGS approach bringing closure to familiesSupported by QIAGEN with expertise and equipment since 2001, the ICMP has built a state-of-the-art DNA laboratory system for the sole purpose of identifying missing persons. Dr. Thomas Parsons leads the technical processes. -
An MPSplex assay for missing persons identificationFelix Bittner, DNA Analyst at the International Commission on Missing Persons (ICMP) discusses his work developing a large massively parallel sequencing SNP panel (MPSplex assay) for missing persons identification. Learn more in this blog post. -
An MPS panel for missing persons identificationIn this webinar, Thomas J. Parsons, Director of Science & Technology at the ICMP, describes working with QIAGEN and academic colleagues to design a MPS assay (MPSplex), targeting over 1200 SNP loci.
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Ready to design your own NGS panel for a human ID application?
Use our custom builder to design a sequencing panel targeting your regions of interest in just a few clicks.
Age estimation and tissue ID
Get more insights
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Identifying unknown non-human DNA samplesIn this Investigator blog, discover how Mirna Ghemrawi, a doctoral student at Florida International University, uses Pyrosequencing-based methylation analysis in species identification. -
Studying chronological aging with DNA methylation analysisIn this Investigator blog, learn how Jan Fleckhaus, Ph.D. student at the Institute of Legal Medicine, Cologne, Germany, optimizes Pyrosequencing technology for routine forensic work and DNA methylation-based age prediction. -
Determining sample age and origin using methylationIn this QIAGEN sponsored webinar, our guest speakers from the San Francisco Police Department (SFPD) Crime Lab and Florida International University (FIU) discuss their research on DNA methylation in body fluid identification and age estimation from DNA left at crime scenes.
Anthropology
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EZ1 solves Bronze Age mysteryDiscover how DNA from 3000-year-old bones was successfully purified using the EZ1 instrument. This purified ancient DNA was suitable for PCR amplification and STR analysis. Genotyping identified familial relationships within the samples, suggesting that the Bronze Age cave where the bones were discovered was a family burial site. -
EZ1 is your solution to challenging bone samplesDiscover how to speed up and improve the DNA yield from bone. Using the EZ1 Advanced XL Instrument, you can reduce the lysis time from the traditional 24 hours to a more efficient 2-hour treatment. Go from sample processing to results within the same working day with this rapid bone protocol.
Featured products – focus on NGS
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GeneRead Size Selection KitFor quick and reliable removal of DNA fragments <150 bp for library preparation in NGS applications -
QIAseq and GeneRead Library Prep KitsFor fast and efficient preparation of DNA libraries for use in NGS applications
