QFT-Plus, QuantiFERON-TB Gold Plus, tubes
TB Management

TB testing with QFT-Plus

What is QFT-Plus?
QuantiFERON-TB Gold Plus (QFT-Plus) is a simple blood test that aids in the detection of Mycobacterium tuberculosis (MTB), the bacteria which causes tuberculosis (TB). It is the simpler, more affordable way to test for TB infection that produces more accurate results than the century-old tuberculin skin test (TST).
Comparison of QFT-Plus and TST for TB testing
    QFT-Plus (1-3)    TST (2,4) 
Single visit assay?  YES  Requires only one patient visit  NO  Requires two patient visits 
Sensitivity?  YES >95% sensitivity – accurately identify
TB-infected patients
NO 70% sensitivity – more missed diagnoses
Specificity? (5) YES >97% specificity – less unnecessary
follow-up and treatment
NO Variable; 59% in BCG-vaccinated populations -
false positives result in  costly follow-up
Objective results? YES Objective and controlled laboratory assay NO Subjective measurement of skin induration
Affected by BCG vaccination? YES Unaffected by BCG vaccination NO Results affected by BCG vaccination
Most cost effective? (6,7) YES More cost effective than TST in multiple
screening situations
NO High program costs due to second visits and
false positives
Improve your TB testing
Switch from the tuberculin skin test to QFT-Plus for accurate and convenient TB detection.
Webinar: Is your TB testing up to date?

Evolving policies and recent technological advances in LTBI testing and treatment represent a new evolutionary step in tuberculosis infection control. Recent publications show the potential of QFT-Plus for at-risk patient populations.

In this webinar, Dr. Masae Kawamura provides an overview of the standard policies and latest scientific advancements in TB testing. She also discusses new preventive treatment regimens and the benefits of QFT-Plus.

Is your TB testing up to date?, webinar
A tested and trusted IGRA for TB detection

Over the past 15 years, laboratory-based TB interferon gamma release assays (IGRAs) have been transforming screening programs with higher accuracy, operational advantages and improved convenience. QuantiFERON technology has been the subject of over 1500 clinical and scientific studies.

QFT-Plus uses an IGRA to measure the T cell immune response to MTB and provides the convenience of a single patient visit with electronic reporting, quantitative results and high accuracy. It is endorsed by the WHO, embraced by the UN and IPPA and among the WHO’s 120 essential diagnostic tests. 

Watch Dr. Riccardo Alagna discuss the performance of QFT-Plus in different patient categories.

  1. QuantiFERON-TB Gold Plus (QFT-Plus) ELISA Package Insert. Current QFT-Plus package inserts are available at www.QuantiFERON.com
  2. Diel, R., Loddenkemper, R., and Nienhaus, A. (2010) Chest 137, 952.
  3.  Harada, N. et al. (2008) J. Infect. 56, 348.
  4. Tuberculin Purified Protein Derivative (Mantoux) TUBERSOL® Package insert. Sanofi Pasteur Limited. February 2013. R8-2013.
  5. Pai, M., Zwerling, A., and Menzies, D. (2008) Ann Intern Med 149, 177–184.
  6. Pareek, M. et al. (2013) Thorax 68, 230.
  7. Nienhaus A, et al. (2007) Arch. Occup. Environ. Health. 81, 295–300.
  8. Turner, J. et al. (1996) Immunology 87, 339.
  9. Brookes, R.H. et al. (2003) Eur. J. Immunol. 33, 3293.
  10. Stenger, S. et al. (1998) Science 282, 121.

*QuantiFERON-TB Gold Plus Blood Collection Tubes by QIAGEN and LIAISON Analyzer by DiaSorin.

Product claims may differ from country to country based on regulations and approvals. Contact your country representative for further details.

QFT-Plus is an in vitro diagnostic aid for detection of Mycobacterium tuberculosis infection. QFT-Plus is an indirect test for M. tuberculosis infection (including disease) and is intended for use in conjunction with risk assessment, radiography, and other medical and diagnostic evaluations. QFT-Plus Package Inserts, available in multiple languages, as well as up-to-date licensing information and product-specific disclaimers can be found at www.QuantiFERON.com.