Novel Applications of NGS in Cancer Diagnostics

This webinar will cover five key areas in which NGS is changing cancer diagnostics:

  • Somatic genomic or epigenomic alterations acquired during carcinogenesis, which may be used for disease classification in combination with conventional morphological classifications
  • Oncogenic driver lesions, which provide molecular targets for prediction of effective and selective therapies
  • Genomic alterations in signal transduction cascades and gene expression patterns, which may be used as prognostic parameters for predicting the need and extent of adjuvant therapy
  • Genomic profiling for differentiating metastases from tumors of unknown primary and correct tumor staging
  • Mutational profiling of circulating tumor DNA, which may enable monitoring the response of tumors to therapy and the development of secondary resistance