Reliable Methylation Analysis for Epigenetic Research

The analysis of changes in DNA methylation presents unique challenges to researchers, especially when dealing with limited and difficult samples (e.g., samples from biopsy and FFPE materials). The challenges are mainly due to the lack of standardized methods created specifically for methylation analysis.

Reasons to attend the webinar:

  • Learn about standardized workflows in epigenetic analyses, with a focus on the critical steps, for example protection of the converted DNA to avoid excessive DNA degradation.
  • Learn about a new method that yields reliable amplification of the entire bisulfite converted genomic DNA (i.e., the bisulfitome). This new method will help overcome the limitations in methylation analysis due to limited DNA amounts.
  • Find out about a newly developed and novel DNA polymerase that enables single base discrimination in methylation specific PCR (MSP) reactions and see experimental data from the enhancement of a highly sensitive TaqMan®, probe-based real-time PCR (MethyLight Assays).
  • Examine various control experiments and how they will increase the success of DNA methylation assays.

See trademarks.

Dr. Gerald Schock, Associate Director PyroMark, QIAGEN GmbH

Gerald Schock

Dr. Gerald Schock is Associate Director for QIAGEN’s Pyrosequencing product line. Dr. Schock studied Biology and Biochemistry at the University of Mainz, Germany and at the University College of Wales, Aberystwyth, UK. He joined QIAGEN after receiving his Ph.D. in 1996, and has held positions in Sales, Regional Marketing, and Global Marketing, where he built up the epigenetics portfolio before assuming responsibility for the Life Science Pyrosequencing portfolio.
Dr. Thorsten Traeger

Thorsten Traeger is a member of the Epigenetics application group where he is involved in the development of the EpiTect product line. Dr. Traeger received his PhD from the Ruhr-University Bochum, Germany and joined QIAGEN 9 years ago, starting in the sequencing department before switching to the Modification and Amplification group, where he is responsible for the development of products and assays for real-time PCR and also for epigenetic applications. Currently, Dr. Traeger is an Associate Director, Project Management R&D in the Modification and Amplification Group at QIAGEN.