Focusing on gene pathways and networks in neurodegenerative disease
Analysis of Alzheimer's disease pathways provides valuable information about risk factors for disease, factors affecting disease outcomes, and possible biomarkers or targets for therapy. While pathways involved in the initiation and progression of Alzheimer's disease are far from completely understood, genes involved in amyloid β protein generation, clearance, degradation, and signal transduction, as well as neuronal toxicity and inflammation, are strong candidates for further study.
QIAGEN offers complete solutions to simplify and streamline each step of your Alzheimer's disease pathway profiling experiments. Pathway- and disease-focused PCR arrays enable quick and easy identification of variations in expression of genes relevant to your research. At GeneGlobe, QIAGEN also offers a broad portfolio of pathway-specific products for a variety of neurodegenerative diseases such as Parkinson’s disease and Huntington's disease, as well as for neurological functions such as neurogenesis or synaptic plasticity.