The EZ1 Advanced in combination with the proven EZ1 DSP Virus Kit enables purification of viral nucleic acid and bacterial DNA from 1–6 samples of human serum, plasma, CSF, urine, whole blood, stool, transport media, respiratory samples, and dried swabs. All processing steps are performed by the instrument — from piercing the reagent cartridge to elution of highly pure nucleic acids. The innovative design of the instrument means that the pipet tips function as separation chambers, increasing the efficiency of magnetic purification and eliminating the need for centrifugation steps. The streamlined procedure provides robust walkaway purification of nucleic acids with minimal hands-on time.