CE-marked as compliant with EU IVD Directive 98/79/EC
Highly accurate results for in vitro diagnostics
Reliable quantification of allele representation
Sequence information enables discovery of rare mutations
1–24 samples can be analyzed in as little as 15 minutes
The PyroMark Q24 MDx uses proven Pyrosequencing technology for real-time, sequence-based detection and quantification for in vitro diagnostic use in Europe. PyroMark Q24 MDx Accessories are used in combination with the PyroMark Q24 MDx instrument.
For 200 reactions: 2x PyroMark PCR Master Mix (includes HotStarTaq DNA Polymerase and optimized PyroMark Reaction Buffer containing 3 mM MgCl2 and dNTPs), 10x CoralLoad Concentrate, 5x Q-Solution, 25 mM MgCl2, and RNase-Free Water.
Methylation detection assay: PCR primers and sequencing primer for quantification of methylation level in region –209 to –181 from the transcription start site in the MLH1 gene