The ipsogen BCR-ABL1 Mbcr RGQ RT-PCR Kit is a quantitative, in vitro diagnostic test for the measure of the BCR-ABL1 fusion gene b3a2 (e14a2) and b2a2 (e13a2) transcripts in total RNA extracted from whole blood.
The kit is intended to monitor deep molecular response in patients diagnosed with chronic phase Philadelphia chromosome positive (Ph+) p210 chronic myeloid leukemia (CML).
The kit is calibrated against the WHO International Genetic Reference Panel and runs on Rotor-Gene Q MDx 5plex HRM using real-time PCR technology. The kit provides all necessary reagents and is optimized for improved sensitive detection and quantification of BCR-ABL1 p210 b2a2 or b3a2 transcripts, relative to ABL1 control gene expression.