GO! direct
From challenging crime samples to reliable DNA profiles
Many high-volume crime samples go untested because there is no funding or time available for sample preparation. Many sexual assault cases lie in storage for months or even years because the effort and complexity of recovering PCR-ready DNA are too great. With the newest Investigator Casework GO! Kit, one can remove the sample purification step which makes the generation of DNA profiles faster and more economical. This can also eliminate the risk of sample contamination due to handling and make DNA testing more viable for a greater number of high-volume crime samples. The use of a direct amplification approach can maximize the chances of obtaining usable profiles from touch DNA and avoid the sample loss inherent in the extraction of such samples. Valuable workflow information, such as the presence or absence of male/total human DNA, sample degradation, or the presence of potential PCR inhibitors, can be obtained when the Investigator Casework GO! Kit is used with compatible downstream Investigator quantification and STR PCR kits.
Micro trace analysis in routine casework
Watch our recent
webinar with Lisa Dierig and learn how direct lysis approaches such as the new
Investigator Casework GO! Kit offers the opportunity to save valuable
biological material from micro traces such as touch DNA or telogen hair roots,
for downstream analysis.
Skin flake analysis in forensic casework
Skin flake isolation provides a solution to avoid mixture deconvolution during DNA analysis and interpretation in forensic casework. However, such trace samples require efficient DNA recovery to enable successful downstream analysis. Pairing skin flake isolation with the Investigator Casework GO! Kit allows direct amplification and an accelerated workflow without the need for further purification, dramatically improving DNA yield.
Get application note
A novel approach for touch traces
The direct lysis approach of the Investigator Casework GO! Kit delivers positive results in STR analysis of contact traces and body fluids. Samples extracted using this innovative method demonstrates a superior DNA yield compared to the automated magnetic bead technology.
Download article