Webinars
Dec 1–2, 2016
Chantilly, France
Conference
Dec 5–8, 2016
Orlando, FL
Conference
The ASH Annual Meeting is the world's premier event in malignant and non-malignant hematology. The meeting provides an invaluable educational experience and an opportunity to review thousands of scientific abstracts highlighting updates in the hottest topics in hematology.
Dec 5, 2016
9:30 AM–10:30 AM (EST)
Online
Webinar
Duration: 1hrs
Real-time polymerase chain reaction (qPCR) is the most sensitive and reliable method for the detection and quantification of nucleic acids. This webinar introduces the concepts of real-time PCR and how to conduct a real-time PCR assay. The topics that will be covered include an overview of real-time PCR chemistries, protocols, quantification methods, real-time PCR applications, and factors for success.
Dec 5, 2016
1:00 PM–2:00 PM (EST)
Online
Webinar
Duration: 1hrs
Exosomes and other extracellular vesicles (EVs) such as microvesicles carry functional cargo and play an important role in disease progression. Recently, exosomal RNAs, especially microRNAs, have attracted tremendous interest as potential circulating diagnostic biomarkers. This webinar presents an integrated system for identification and characterization of specific RNA molecules from exosomes and other extracellular vesicles (EVs). Advanced assay technologies for characterization of the RNA profiles including mRNA, microRNA and long non-coding RNAs (RNAs) from serum exosomes will be introduced and discussed.
Dec 6, 2016
1:00 PM–2:00 PM (EST)
Online
Webinar
Duration: 1hrs

miRNA plays a critical role in many biological processes such as differentiation and development, cell signaling, response to infection, and more. Recent studies have shown overwhelming evidence that aberrations in miRNA regulation are causal or indicators of many disease processes. Currently, there is a race to find and develop miRNAs as biomarkers and therapeutics. To win the race, it is important to have a strong understanding of miRNA and the challenges of miRNA research.

The webinar will cover the biology of microRNA, the key challenges associated with microRNA research, and the latest advances in microRNA research technology.

Dec 7, 2016
9:30 AM–10:30 AM (EST)
Online
Webinar
Duration: 1hrs

Targeted DNA sequencing has become a powerful approach as it ensures high coverage of the region of interest, while keeping the cost of sequencing and complexity of data interpretation manageable. However, existing PCR-based target enrichment approaches introduce errors due to PCR amplification bias and artifacts, which significantly affect quantification accuracy and limit the ability to confidently detect low-frequency DNA variants. This webinar introduces a new digital sequencing approach that is based on the use of unique molecular indices (UMIs) – QIAseq Targeted DNA Panels. With UMIs, each unique DNA molecule is barcoded before any amplification takes place to correct for PCR errors. Detailed workflow and applications in cancer research will be presented. Join us and learn about this exciting and novel digital DNA-seq technology.

Dec 7, 2016
1:00 PM–2:00 PM (EST)
Online
Webinar
Duration: 1hrs

A biomarker is a characteristic that can be measured and evaluated as an indicator of a normal biological process, pathological process or response to therapy.  Biomarkers can either be DNA- or RNA- based, or even both.  Recently, transcriptional biomarkers, which are based on gene expression analysis, are gaining greater importance in clinical research.  Transcriptional biomarkers provide information on the latest physiological status of the microenvironment and the response of cells to external or internal factors.  The development of RNA sequencing, digital RNA sequencing and new bioinformatics tools enables us to identify, confirm and validate transcriptional (both mRNA and miRNA) biomarkers, , with a high level of accuracy.

 

Limited sample amount, low-quality sample and large sample numbers are some of the common challenges faced by labs undertaking biomarker discovery.  In addition, tight timelines and the lack of in-house expertise and facilities also hamper the use of the latest technologies.  In this webinar, we will give you an overview of applying RNA sequencing strategies and techniques to biomarker discovery.  The webinar will also discuss when to use whole transcriptome or mRNA sequencing and the application of bioinformatics solutions such as CLC Genomics Workbench and Ingenuity Variant Analysis in biomarker discovery. 

Dec 8, 2016
1:00 PM–2:00 PM (EST)
Online
Webinar
Duration: 1hrs

Next-generation sequencing (NGS) is a driving force for numerous new and exciting applications, including cancer research, stem cell research, metagenomics, population genetics, medical research and single cell analysis. While NGS technology is continuously improving, library preparation remains one of the biggest bottlenecks in the NGS workflow and includes several time-consuming steps that can result in considerable sample loss and the potential to introduce handling errors. Moreover, conducting single-cell genomic analysis using NGS methods has traditionally been challenging since the amount of genomic DNA present in a single cell is very limited.

 

In this webinar, we will provide an overview of methods for the preparation of high-quality DNA libraries directly from high-molecular-weight DNA using innovative enzymatic fragmentation that is integrated in the DNA end-repair step. We will discuss complete PCR-free solutions for whole genome and whole transcriptome sequencing from isolated single cells and low amounts of genomic DNA or RNA. Additionally, we will provide details on a time-saving, one-tube library preparation protocol that does not require extra nucleic acids fragmentation and sample cleanup between steps, minimizing starting material loss and cross-contamination risk, thereby increasing the resolution of NGS data.

Dec 12, 2016
9:30 AM–10:30 AM (EST)
Online
Webinar
Duration: 1hrs
This webinar presents a simple yet accurate approach to study pathway- and disease-focused mRNA and long non-coding RNA (lncRNA) expression profiling using real-time PCR. Learn about the stringent performance standards built into the technology to ensure sensitivity, specificity, reproducibility and reliability. These advantages and features will be presented using application-based examples.
Dec 12, 2016
1:00 PM–2:00 PM (EST)
Online
Webinar
Duration: 1hrs
The increasing demand for streamlined, monitored and ultrafast qPCR procedures requires high-performance, real-time quantitative RT and PCR chemistries. This webinar presents innovative solutions for one-step and two-step RT-PCR that significantly enhance performance and reliability in qRT-PCR. Internal Control RNA, removal of genomic DNA, room temperature set-up capability for RT-PCR and a built-in visual pipetting control verify accurate procedures, ensuring reliable gene expression profiling.

This webinar explains the principles of the technologies and shows data demonstrating performance in qRT-PCR. Find out how you can verify accurate performance in qRT-PCR and improve your results.
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