Pinpointing miRNA profiles and roles in Alzheimer's disease
Overwhelming evidence indicates that dysregulation of miRNA expression is a cause or indicator of several disease processes. The discovery that circulating miRNAs are detectable in serum and plasma, and that their expression varies as a result of disease, presents great potential for circulating miRNA expression signatures to be used as biomarkers in disease diagnosis and prevention. Ready and minimally invasive access to blood samples, as well as miRNA stability and ease of detection, make circulating miRNAs attractive for detailed investigation.
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