DNA Methylation Analysis

Epigenetic Regulation
Deciphering methylation differences in neurodegenerative disease
Epigenetic changes are likely involved in pathogenesis of Alzheimer's disease. Epigenetics studies may provide a valuable link indicating environmental and non-genetic causes of this disease. However, further studies are needed in this area to screen, identify, and quantify relevant CpG sites in methylation analysis.
For fixation and stabilization of human tissue specimens (max. 4 x 15 x 15 mm in size)
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For low- to medium-throughput sample disruption for molecular analysis
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For immediate stabilization of DNA, RNA, and protein in tissues
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For blood collection prior to genomic DNA purification using the PAXgene Blood DNA Kit
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For purification of up to 12 µg genomic, mitochondrial, or viral DNA from blood and related body fluids
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For fully automated sample prep using QIAGEN spin-column kits
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For isolation of genomic, mitochondrial, bacterial, parasite or viral DNA
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For purification of DNA from tissues fixed and stabilized in PAXgene Tissue Containers
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For purification of up to 500 µg genomic DNA from whole blood
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For purification of genomic DNA from formalin-fixed paraffin-embedded tissues
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For ultrafast, highly efficient bisulfite conversion from gDNA, FFPE, blood, cell, or tissue samples
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For fast and effective chromatin immunoprecipitation
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For whole genome amplification of bisulfite converted DNA for PCR analyses
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For PCR amplification of template DNA optimized for Pyrosequencing analysis
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For application-focused DNA methylation profiling using MethylScreen technology with laboratory-verified assays
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For advanced methylation and mutation quantification in long sequence runs using Pyrosequencing
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Predesigned assays for quantification of CpG methylation by Pyrosequencing
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For application-focused quantitative detection of gene panels in chromatin immunoprecipitation experiments
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