The most important pathways
QIAGEN provides a broad range of assay technologies for toxicology and pharmacology research, enabling analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction pathway activation. The understanding of drug–body interactions is crucial to drug development. Drug absorption, distribution, metabolism, and excretion (ADME) is critical in all phases of drug development programs, providing key insights into how a drug will ultimately be treated or accepted by the body. In the late 1980s to the mid-1990s, 40% of all drug failures in clinical trials were due to unfavorable toxicology and ADME profiles. By developing and using new focused genomic tools, researchers are better prepared to test compounds to protect human health and the environment. Solutions optimized for these research studies are organized into more focused research topics, shown below.