Can the QIAvac 96 vacuum manifold be used with DirectPrep 96 plates?
FAQ ID -722

No. The DirectPrep 96 plate of the DirectPrep 96 Miniprep Kit cannot be securely positioned in the QIAvac 96 vacuum manifold, and the nozzles may not fit into the correct wells below. Furthermore, adapters are needed to position Elution Microtubes or Microplates in the correct height for elution. If the distance of the "receiving" plate to the nozzles is not optimal, splashing and thus cross contamination can occur. Due to these difficulties with fitting, tightness and potential cross contamination, we do not recommend using the QIAvac 96 with the DirectPrep 96 System.

We recommend to use the QIAvac Mulitwell vacuum manifold in combination with the DirectPrep 96 Miniprep Kit.